Donna tries to make up with David, whose increased drug use turns her away. David also steals $150 from his father to buy more amphetamines for himself. When his drug dealer is arrested later, he finds himself in possession of a huge stash of narcotics and calls on Dylan for help. Meanwhile, Jesse and Andrea meet with her grandmother to get her blessings before their wedding and reception at the Peach Pit. A dangerous affair begins between Brandon and Lucinda, who shows her true colors when she starts teaching her anthropology class of human sexuality and preaches the need for multiple partners, seeing sex as her personal weapon. Brenda gets a surprise visit from a long-absent Stuart on Valentine's Day.

Brandon and Dean Trimble are caught in the middle of a conflict when several Jewish students, including Andrea, protest the scheduled campus appearance of a controversial, anti-Semitist, African-American orator, in which the demonstrations and near-riots disrupt Kelly's photo shoot for the magazine. Meanwhile, Donna plans a party for Ray's 25th birthday. In the hospital, Dylan spends the time talking with his mother Iris, while his drug dealer pays an unexpected visit and threatens him not to tell the police about their business.

Brandon and Clare have the same bad dreams involving "Jeopardy" host Alex Trebek and announcer Johnny Gilbert while competing with each other and Andrea for a spot in the show's college tournament. After learning from Andrea about her affair, Jesse moves in with Dylan and talks about the possibility of divorce while Dylan tries to reason with him to make up with her. Meanwhile, the reconciliation of Mel and Jackie gives David hope of reuniting with Donna whom he still has feelings for.