Having reestablished control over the Company, Angela sends Nathan and Peter to Haiti to find the power-suppressing Haitian to bring him back to the USA to help in their fight against Arthur Petrelli and the evil Pinehurst. Hiro and Ando travel to New York to come back into the fold and ask for Parkman's help. Hiro, having lost part of his mind, but not his powers, teleports himself, Ando and Parkman to Kansas to Daphne's home to find out what Mr. Petrelli has on her. Also, Sylar teams up with Elle to try to capture Claire to bring her to Pinehurst to give her to Suresh to experiment on as the missing catalyst to the formula. But everything changes when a prolonged solar eclipse happens, which renders the heroes and villains powerless, stranding Peter and Nathan in Haiti with the Haitian who is trying to capture the powerful Voodoo witch-doctor Baron Samedi. In Kansas, Parkman must find a way into the Millbrook house without his mind-reading powers, and learns what Daphne is without her super-speed powers. In California, the powerless Elle and Sylar try to capture Claire, who accidentally gets shot, and Nathan seeks revenge.

In Haiti, Peter and the Haitian try to rescue Nathan who has been captured by the sinister Baron Samdei and his militia army. At Pinehurst, Mohinder finds himself a captive by Arthur who wants his powers back for a grand master plan, in which Mohinder attempts to find Maya to ask for help since she may be powerless too. In Kansas, Matt Parkman learns the true nature of Daphne without her super speed, while Ando and an immature Hiro seek answers to their powerlessness in a comic book store in the late Isaac Mendez's '9th Wonders' series detailing their conflict as it happens. In California, the powerless Claire is taken to the hospital dying from her wounds, while Sylar and Elle turn from hunters to the hunted when the vengeful Mr. Bennet attempts to track them down to kill them.