Lucy finally admits to Carter that she doesn't know how to start an IV. Weaver interviews for the job as the ER Chief. Benton keeps his son's disease a secret. Jeanie intervenes when she finds out a liver transplant candidate is drinking again, and later asks Doug if she can be assigned to work for his pedes project in the ER. Corday gets stuck as the intern of dismissive and insulting Dr. Dale Edson.

The board decides to extend the search for a new ER Chief, leaving Kerry waiting for a decision. Benton visits a doctor who is deaf and he realizes that there is nothing "wrong" with his son. Mark saves the life of a gay prostitute and then tries to get the kid to avoid reckless behavior. Carter loses his Resident Advisor job because of Lucy, then blames her for not going along with his plan to defraud an insurance company, but she inadvertently leads him to shave off a nasty-looking beard he'd been growing. Corday saves two lives and impresses Benton enough that he decides to request she be his intern instead of Dale's. Carol tries to help an elderly Jewish guy find a place to live.

Carter and Weaver become unlikely roommates. Lucy is having problems with Carter, and Greene picks up on their squabbling. Corday works long shifts which leads to her exhaustion and a critical medical error, causing a rift with Dr. Anspaugh and problems for Benton. Greene has unpleasant flashbacks when he's hazed by the well-meaning paramedics. Jeanie worries when she and Doug treat a young boy whose childlike mother clearly depends on his 6-year sister to make all decisions. Kerry rediscovers her joy of practicing medicine and decides not to pursue the open ER Chief job, which goes instead to a Dr. Amanda Lee.

Corday faces M&M where the board was discussing the mistake that Corday made after she gave the wrong dosage to a patient. She decides to take the offensive and let the board know how wrong it is for her or any other doctor to work 36 hours. The board decides to do nothing about it, and she later decides to amicably end her relationship with Benton. At the hospital arrives Ruth Johnson who was born 100 years ago in that same hospital and shares some experiences with Carter. Carol is horrified by the truth behind a young boy's fatal shooting.

Lucy begins her surgical rotation under Benton and Corday. Romano offers to get Corday's fellowship reinstated and asks her to assist him in surgery. Weaver interrogates Corday, asking if Romano ever sexually harassed her. Corday denies it and concludes that Doyle must have filed charges. Ross jeopardizes a liquid pain medicine study by surreptitiously giving some of the drug to Joi's son, Ricky. Greene discovers the secret and informs Weaver. They decide not to tell Anspaugh because, by violating protocol on a federally-funded trial, the hospital would be unable to obtain research money and Medicare payments for years.

When a school bus becomes involved in an accident, Mark assists paramedics with treating injured children; Weaver makes a discovery regarding a colleague.

Romano observes the ER, and rubs the staff the wrong way. Lucy finds out that an elderly patient's bedsore is really much more. Carter breaks up with his girlfriend. The power goes out at County General, and the doctors must keep critical patients alive. Corday investigates the rape of a comatose patient.

A recommendation from Weaver allows Jeanie to have temporary approval as a foster parent for baby Carlos. Reggie and Jeanie get married. Lucy and Kovac talk with a young woman whose husband they believe is very dangerous.

Hathaway befriends an out-of-work waitress, Meg. Seven-months pregnant, Meg cannot afford prenatal care. Hathaway invites her to the hospital, performs free tests and helps her interview for a job in the cafeteria.

A prank in a high school science class goes terribly awry, injuring a teacher and several students. Hathaway discovers Meg's drug addiction. Weaver and Greene notice Lawrence gets easily confused.

In order to get her patient to tell her the location of a missing body, Corday agrees to grant him a fatal wish. Kovac befriends two brothers. He tells Weaver that his wife and children died in the Bosnian war. Former medical student Deb Chen returns to County General as a resident, using her Chinese name, Jing-Mei Chen.

Lucy's patient finally gets the call to receive a heart transplant, but there are complications. Greene interferes in a gay couple's domestic situation. Corday tricked her patient who murdered several women and now he's being transferred to a county jail.

Carter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.

After Corday refuses to perform exploratory surgery on Cleo's patient, Cleo enlists Benton's help, infuriating Corday. Abby cares for a pregnant woman with five children who wants an abortion. Greene lovingly tends to his dying father at home.

Weaver reprimands Carter for doing a dangerous procedure without consulting Kovac. She also talks to Hathaway about Hathaway's lack of focus on the job. And while treating a 6-year-old patient involved in a minor car accident, Malucci and Cleo discover the girl has been sexually molested recently by her father.

Dr. Carter is allowed a cautious restart with small steps. An extremely blond Dr. Malucci is very curious who's made Dr. Chen pregnant. Dr. Benton has been written out of all the hospital's systems and is stunned by Dr. Romano. An unfortunate incident at a Science Fiction convention makes it look like scenes from the movie 'Mars Attacks'.

Chen gives birth, but insists on breastfeeding the infant before she gives it to the adoptive parents. Greene and Corday consult a brain specialist in New York City who believes the tumor can be safely removed. Stressed and tired, Carter impulsively swallows two painkiller pills but intentionally vomits them. He confesses to Abby.

Benton and Cleo clash over his deceased nephew's girlfriend. They finally agree to call a social worker. Benton confesses his love to Cleo. The spinal surgery malpractice suit is settled by employing a technicality: the equipment used was later recalled by the manufacturer. But Corday now doubts her abilities as a surgeon.

Greene returns to work but confuses words and displays uncharacteristic anger. Eager to get out of his per diem situation, Benton agrees to a full-time position. Carter visits his cousin, who became paralyzed after a drug overdose. A workplace disaster results in numerous injuries and fatalities among illegal immigrants.

Weaver becomes concerned about Greene's cognitive skills and surreptitiously calls for an official evaluation of his competency. Corday plans her wedding to Greene. Bishop Stewart returns, and Kovac realizes the man has a terrible disease. Dateless for a charity function, Carter invites Abby to attend with him.

In the series' 150th episode, a massive train wreck mobilizes the emergency room doctors. Corday, Carter and Kovac rush to the scene. Corday falls and injures her back, bringing on contractions in only her 25th week of pregnancy. While amputating the legs of a fallen firefighter, Corday stops because of her pain.

Numerous mishaps threaten to mar Corday and Greene's wedding day. As the very pregnant Corday becomes increasingly agitated, the presence of her bickering divorced parents does little to improve her mood. With the intense rain, Greene has a difficult time making it to the church. But, evenutally, he arrives and they joyfully wed.

Abby and Carter travel to Oklahoma to rescue Abby's mentally ill mother and bring her back to Chicago. In Chicago, Maggie suffers from a sleeping pills overdose. At County General, Kovac frantically revives her. Benton treats a college student injured in a fraternity prank.

Maggie contests Abby's attempt to institutionalize her. Weaver treats a few bizarre patients. When Legaspi returns to work after being exonerated of sexual harassment, Weaver tries to reconcile with her. Benton injures his hand while transporting his former teacher to the hospital and must contend with the teacher's wisecracking elderly buddies (TOM BOSLEY and TOM POSTON).

The ER is flooded with foster care home residents, attacked by a shooter bent on tracking down his son, who , with the help of Dr. Green, was put into the foster care system amid allegations he was being abused by his father.

Weaver returns to the emergency room after a self-imposed sabbatical of three weeks, wondering how her newfound lesbian identity will affect her workplace relationships. Having purposely allowed a mass murderer to die, Greene must keep the secret amidst the scrutiny of his superiors.

Dr. Susan Lewis arrives, looking for work in the Chicago area again. Greene hires her, over Weaver's objection. Chen nervously attends a risk management review, accompanied by the unforgiving Weaver, to discuss a patient who recently died under Chen's supervision.

An accidental overdose brings Drs. Green and Corday's baby into the ER.

Greene confronts Corday when she orders Rachel out of their home; Abby tries to protect a battered neighbor who refuses to press charges against her husband.

Drs. Corday and Greene are awkward when working together in the ER. Dr. Weaver treats victims of an intense fire that may take the life of a dear friend.

Just when the ER is understaffed and swamped, two children who were brought in turn out to have full blown smallpox. The entire ER must be locked down. The staff needs to improvise while they battle not only the disease but also frayed tempers.

Dr. Carter, Abby and other staff of the ER are quarantined as the CDC investigate a mysterious, deadly outbreak.

After another hospital shuts down, the ER is flooded with patients. Dr. Pratt resuscitates a heart-attack victim who had been pronounced dead.

Dr. Carter leads a walk-out of staff protesting lack of security in the ER.

Abby comes close to breaking down trying to deal with her mother. Dr. Pratt goes for his required paramedic ride-along. Dr. Weaver confronts the man who stole her purse. Dr. Lewis has a teen admirer.

Dr. Romano seizes control of the ER and manages to offend everyone. Dr. Kovac asks Dr. Corday's help in the quest to bring a sickly Croatian boy to the U.S. for medical treatment.

Dr. Carter tries to prevent a grieving gang member from going after vengeance. Dr. Kovac races against time to save a Croatian boy's life. A baseball player gets treatment for a heart problem.

It's Greg Pratt's last shift at County General and he treats a number of cases that were started by John Carter on the day shift. They treat a 12 year-old near drowning victim who has little chance of recovery; a Buddhist nun who has a special gift of seeing another's inner self; a woman who is convinced that the day's solar eclipse signals the end of the world; a drug addict who scams both of them for pain medication; and a pregnant woman who had her baby torn out of her womb. Dr. Romano has his re-attached arm amputated. Carter receives a call from Luka Kovac asking if he can come to the Congo and help out. Abby is none too pleased. Meanwhile, Doc Magoo's burns to the ground.

Neela helps treat two Amish teens who were in a car crash. Sam argues with Dr. Kovac when he pays too much attention to her son.

Carter returns from Africa full of surprises including a new love, Makemba ("Kem"). Pratt accidentally breaks a patient's neck while doing an unsupervised intubation. A whole nursing shift cannot go home until they find one missing Valium.

Dr. Carter's girlfriend makes an impression as she observes ER operations. Dr. Gallant is almost shot during a domestic incident. Dr. Weaver dedicates a center to the memory of Dr. Romano.

Dr Morris agitates a patient who then leaves, steals a tank, and rampages through Chicago on his way to County General. He makes it all the way to the ambulance bay before the CPD finally stops him. Sam tries to figure out her relationship with Kovac while Gillian shows up at the ER to cement plans for dinner with Carter, Kem and Kovac - making things that much more difficult. Neela confronts Frank about his arrogant bigotry, bluntly telling him she wants nothing from him but silence from this point forward. During the initial onrush of patients due to the tank rampage, Frank has a heart attack which is, thankfully, caught. Frank's wife and daughter show up and are rushed up to the cath lab where Dr. Pratt is helping Dr. Kayson keep Frank alive. In the end, Neela winds up in the family room with Frank's family listening to them describe a side of Frank that no one has ever seen. Meanwhile Kovac treats a 13 year old with chlamydia and counsels him to contact his sexual partner - which turns out to be quite a few teenage girls.

Weaver rushes to the aid of her wife, Sandy Lopez, when the firefighter is severely injured while working and must now battle for her life. Frightened Weaver whispers hope to Sandy by reminding the victim of their newborn child.

Carter greets the returning Kem, but their meeting with his father, Jack, gets tense after Carter announces plans for his grandmother's estate.

Kovacs stops to help a woman and her son whose car broke down. Steve is getting close to Alex, and Sam panics. Abby is looking for her letter whether to see she passed her boards. Pratt shows off his new Chrysler. Elgin tries to build a connection between him and Pratt. Jing-Mei might be battered by her senile father.

After being shot at, Pratt, Jing-Mei and Elgin are trying to get out of their sinking car. Sam took Alex with her while fleeing from Steve. Kovac is considering going after them. Abby wants to go to bed since tomorrow is her first day as a doctor, but is thwarted by Weaver, whose custody battle might take a dramatic turn. A young drug dealer is brought in with "a foreign object" in her tunnel of life.

A rape victim, barely able to speak, does all she can to help police find her attacker.

Neela treats a religious teenage girl who turns out to be pregnant. Abby and Kovac struggle to figure out what to do with her unexpected pregnancy.

Weaver contemplates hip replacement surgery after she finds it hard to do her labor-intensive job. Meanwhile, Kovac tries to ease Abby's fears about raising a child together. Neela decides to attend a support group for military spouses but when she offers her opinions on the war, the meeting turns into a debate. And after Sam treats a fainting victim, she finds herself with an intriguing job offer.

Pratt struggles to get a straight story when two abused boys come into the ER with their father. Two U.S. Army officers enter the ER.

In 12 hours, the ER will shut down. As Kovac is under pressure to take care of the patients before the final hours, he makes a pivotal decision about his future. Meanwhile, Sam befriends a photojournalist who returns only this time she's terminally ill; Pratt is concerned when his brother ends up in the ER drunk; Morris confronts Gates when he ignores his orders and angrily sends him home while Gates tries to defend his actions.

Gates and Julia nurture their newfound romance but are soon interrupted by a troubled phone call from Gates' ward, Sarah.

As Carter prepares to open a new facility for the underprivileged, some old friends/colleagues gather. Rachel Greene, Mark Greene's daughter, applies for an internship at County.