The white-picket-fence world of the Hart family collapses when Texas soccer mom Reba discovers that her dentist husband Brock is leaving her for his impossibly perky and unfortunately pregnant dental hygienist Barbra Jean. As if that bombshell isn't enough, Reba also learns that her 17-year-old daughter Cheyenne is pregnant by her boyfriend Van. Concerned with the effect all this chaos will have on 12-year-old Kyra, and 9-year-old Jake, and determined that her family will muddle through this domestic mess together, Reba summons her courage and plans a shotgun wedding while trying to keep the husband-stealing future stepmother of her children at arm's length

With Cheyenne & Van back from their honeymoon, they return to school. The principal wants the pregnant Cheyenne to consider a different school. Reba says if Cheyenne cannot attend, Van does not attend. Van is the star football player.

Everyone has a hard time adjusting when Van moves his belongings into the Hart household, on the same day that Reba discovers that the obstetrician she has chosen for her daughter Cheyenne will also be delivering the baby of ex-husband Brock and his mistress Barbra Jean.