CJ cannot control her outrage when the US agrees to an arms sale to Qumar, a country that brutally abuses women. Josh meets with Amy Gardner, a leading women's group lobbyist. The content of a Smithsonian exhibit draws protest from a veteran's group. Leo and the President discuss options when the possibility of a Mad Cow infection strikes the US beef industry.

In a private, late-night meeting, Cliff Calley informs Leo and Jordon he has negotiated a settlement in the Congressional witch hunt over Bartlet's MS: Bartlet can accept a joint congressional censure (House Concurrent Resolution 172, or H.Con. 172); Leo initially refuses to bring it to the president, insisting it will devastate the president and affect him for the rest of his life, but he does mull it over, and consults with Josh and repeatedly with Jordon about it; Josh begins his romantic pursuit of women's issues advocate Amy Gardner, but flubs it a couple of times while she continues dating other men.

On the night of the State of the Union, Sam has to explain the process of writing the speech and grading reaction to it to a magazine reporter (Traylor Howard) throughout the evening; C.J. arranged the coverage aware that the reporter, Lisa Sherbourn, is Sam's ex-fiancée; flashing back to the speechwriting process, we see the president dining with several of Abbey's medical colleagues, and they ponder the future of cancer research, motivating Bartlet to ask that a section be added to the SOTU in which he calls for U.S. scientists to find a cancer cure by 2012; the staff, convinced that the Congressional censure is weighing heavily on the president, tries to talk him out of this bold but risky proposal.

Toby is concerned when President Bartlett forgoes an opportunity to speak out in favor of affirmative action during the Iowa caucuses and confronts the President on the real reasons underlying his Dr. Jekyl & Uncle Fluffy personality shifts. Meanwhile Josh makes plans for a vacation with Amy and then must cancel them.

A lavish W.H. party for Abbey's birthday the night before a N.H. medical board begins hearings on whether to suspend her license over her secret treatment of her husband's MS. Abbey returns to the residence with C.J. and Amy Gardener to get blitzed on wine and discuss her concerns about her medical career. Donna is restricted from joining the party because a decades-old cartography error puts her birthplace in Canada. Toby and U.K. Ambassador Lord John Marbury (Roger Rees) go to a nearby bar to share a bottle of very rare Scotch and to discuss a planned W.H. visit by an IRA political activist, which culminates in Marbury surprising Toby with his progressive vision. Later, Donna joins the women in the residence and makes an off-the-cuff remark that causes Abbey to rethink her stance on the issue of her license.

Bartlet and Leo debate on how to deal with the impending visit of the Qumari Defense Minister, whom U.S. intelligence officers have conclusively linked to terrorists. Sam dismisses an ingenious idea to trap Republican presidential opponent Robert Ritchie in an unsavory position over the Everglades, but comes around after talking to Toby. C.J. begins to develop a relationship with Secret Service agent assigned to her, Simon Donovan. Josh and Amy are locked into a battle over a welfare reform bill, which could end their relationship.

Bartlet, Leo, Sam, Toby, and C.J. travel to New York City for a Catholic fund raiser at a long Broadway play called "The War of the Roses". Josh steps up his efforts to beat his girlfriend, Amy, in their struggle over the welfare reform bill, which leads to her forced resignation. C.J. and Secret Service agent Simon Donavon have grown closer, but a tragic event cuts short their relationship. At the play, Bartlet comes face to face with Republican Presidential candidate Rob Ritchie and faces the decision of whether or not to assassinate the Qumari Defense Minister.

Josh and Toby have a plan to make college cheaper. Leo starts talking to a lawyer about the Shareef assassination. A judicial ruling on third-party candidates has troubling implications for the campaign.

A possible third-party candidate threatens to upset the President's lead in the polls. As Qumar threatens to blame Israel for Shareef's death, Leo must convince the Israeli ambassador not to respond. Charlie teaches his new ward a lesson in basic government. When the committee in charge of presidential debates rules that there will only be two, Sam and CJ propose a risky strategy.

Sequestered in North Carolina to prepare for the one and only debate between Bartlet and opponent Robert Richie, the staff and several consultants (incl. Andrea Wyatt and Joey Lucas) flash back to the days just before and after the president's first inauguration, which were marked by an ill-advised choice for attorney general and ongoing concerns about fertility for then-married Toby and Andrea. In the present, Sam plays Richie in mock debates and raises Bartlet's ire, while Leo and the joint chiefs try to convince the president not to treat increasingly aggressive Qu'mar, whose defense minister Bartlet ordered assassinated (late last season), with kid gloves, and the staff keeps pestering Toby about his on-again, off-again relationship with Andrea, until he makes a startling revelation.

Sam finds himself in a tricky position after the election in Orange County takes an unexpected turn. Toby and his ex-wife also find themselves in a delicate position, but decidedly one of their own making. And CJ tracks down the self aggrandizing source of some Process Stories.

Women's groups, by default including the majority of the First Family, react passionately as a renowned female fighter pilot is sanctioned for an affair with a senior officer. Meanwhile Sam prepares for his campaign.

Military action in Africa has unforeseen repercussions. Sam and Toby work together on the Orange County Campaign. Will has to find his leadership skills quickly as he is left with no one but interns to prepare remarks on the dry subjects of Taxes.

Amy is challenged and tormented from all sides in her first day as Chief of Staff to the First Lady. Her first task is to prove that Abbey's relative was a privateer and not a pirate. And a glacier melts!

The assassination of Shareef threatens to become public, the president speaks at Zoe's graduation, and the unthinkable happens.

In the wake of his daughter's kidnapping, Bartlet must make a decision between being a father and being President.

Zoey Barlet has been held for over a day. An international crisis looms that could have serious repercussions for the administration, let alone the hostage.

With Bartlet back in the Oval Office, and back in his wife's bad books, the hunt for a Vice President begins.

A North Korean pianist announces his intention to defect in the Oval Office. While the staff passionately debate his request they also fight to get the President's choice of Vice President nominated by a new and hostile Speaker of the House.

Multiple members of the team start questioning the direction of the White House, including one member entertaining job offers. Those who aren't are starting to stumble, including Josh and Amy.

Five days before the New Hampshire Democratic primary, the Santos campaign risks extinction as Matt has not been invited to the last debate. Josh proposes a number of strategies to get Santos into the debate, including deal-making, legal challenges, attack ads, and publicity stunts - but the Congressman is reluctant to play along. With Josh scrambling to keep the campaign alive, Santos calls in help from Washington to tune his message. Hoynes and Russell launch attack ads on each other's records, and Josh realizes that a desperate long-shot is needed to keep Santos in the race.

President Bartlet and his current and former staffers come together for Leo's funeral.

While Santos is wrapped up in choosing his new Vice President, Helen is overwhelmed by the issues facing the new First Family. Meanwhile, Vinick must find a new road now that the election is over.