While Oliver tends to the Canary's wounds, he tries to get her to talk about where she came from but she refuses. However, after Oliver and Canary are attacked at the Queen mansion by a trained killer from the League of Assassins, she confesses to how she's connected with the nefarious group. Meanwhile with Moira facing multiple counts of murder and conspiracy for her part in the destruction of The Glades, the Assistant District Attorney offers her a choice - plead guilty now and avoid the death penalty or take your chances in court. Thea begs her mother to fight for her life but Moira seems resolute about taking the offer. Meanwhile, Oliver is furious with Laurel for joining the prosecution's team on his mother's case.

Amanda Waller sends A.R.G.U.S. agents to kidnap Diggle. Waller informs Diggle that Lyla has gone missing after following a lead on Deadshot in Moscow. When Diggle tells the team he's headed to Russia to rescue Lyla, Oliver and Felicity decide to join, but things get messy when Isabel shows up on the tarmac and insists on joining Oliver's "work trip". Meanwhile, Moira's lawyer, Jean, tells Thea that dating Roy, a known criminal, is hurting her mother's case.

Oliver is concerned when a mysterious illness sweeps the city, infecting hundreds of people, including Diggle. Oliver discovers Vertigo in Diggle's blood and realizes The Count has broken out of prison and is once again distributing his drug. Meanwhile, Moira goes on trial for her participation in the Undertaking. ADA Adam Donner collapses in court with Vertigo symptoms so Laurel must step in and try the case against Moira. Oliver is torn between standing by his family during the trial and catching The Count. However, things change when Felicity follows a lead and walks straight into a trap set by The Count.

After an impossible break in at Queen Consolidated, CSI Barry Allen comes to Starling to help with the investigation, Sin asks Roy for help so Thea tags along.

After a fight with Cyrus Gold, aka the Acolyte, Oliver is drugged and left for dead. Determined to cure him, Felicity makes a risky decision. The cure causes Oliver to hallucinate, and what he sees forces him to confront his past. Meanwhile, Barry Allen continues to help Felicity, and their connection grows stronger. The Arrow asks Quentin to look into Gold, but when the stakeout on Gold goes bad, someone is killed. Roy is captured and tortured by Brother Blood.

Oliver must tackle a new threat to the city when bombs start to go off in Starling City. Felicity discovers the person setting them off is Mark Scheffer, a man who goes by the nickname Shrapnel. The Arrow discovers Shrapnel's next target is Sebastian Blood's "Unity Rally" and tries to talk the alderman out of hosting it, but he refuses. The Arrow sets off to stop the bombing, but Shrapnel tricks him and traps him in a bomb-laced antique store where he is unable to move without setting off the device. While Felicity helps Oliver, Diggle races to the plaza to find the bomb before it goes off. Meanwhile, Roy continues to hide his new strength from Thea but, after she witnesses his super strength in action at the rally, she demands answers. Laurel's suspicions about Sebastian grow stronger once she learns that he grew up with Cyrus Gold, the man who killed Lance's partner. After Donner refuses to help her investigate, she turns to The Arrow for help.

When Laurel asks the Arrow to investigate Sebastian Blood, Oliver is unsure whether to believe her accusations. But when they get too close to the truth, Blood strikes back.

Oliver is shocked when he learns that Slade has come to Starling City. Back on the island, as Oliver, Slade and Sara prepare to take over the freighter from Ivo, Sara pulls Oliver aside and tells him he needs to kill Ivo to prevent him from telling Slade what happened with Shado. Oliver feels immense guilt over the situation but realizes Slade's growing rage from the Mirakuru makes him unpredictable and he could turn on his friends if he thinks Oliver is to blame. Oliver agrees to kill Ivo and the battle begins.

After taking a ride home from Slade, Thea becomes his prisoner. Can Oliver and his friends save her? Also, someone close to Oliver is working for Slade, since his return from the Island after Tommy's death.

Oliver, Canary, Diggle, and Felicity return to the lair and find Slade waiting for them. An epic battle breaks out and one member of Team Arrow is sent to the hospital. Thea hits her breaking point, but just as Oliver is about to reach her, Slade intervenes and Oliver is faced with a choice - his battle with Slade or his family. Meanwhile, Laurel struggles with a new secret.