Stargate Command is approached by representatives of Jonas Quinn's home planet seeking military hardware. Their world is divided into three territories and there is a long history of war among them. Jonas' country fears that the other two territories are about to sign a non-aggression pact thus making them vulnerable to attack. In return for arms, they are offering an abundance of Naquadria. SGC isn't about to get involved in what amounts to a civil war but there's another possible outcome when Jonas' one-time professor, Doctor Kieran, tells them of an underground movement ready to overthrow the government and seek out a lasting peace. SG-1 travels to Jonas Quinn's home planet to obtain information on the situation there but not all is as it seems.

On a shakedown cruise of the Prometheus, the ship's hyperdrive regulator becomes irreparably damaged. A nearby planet was listed on the cartouche of addresses found on Abydos and thus may have a stargate. After a short jump towards the planet, the Naquadria reactor overloads and must be jettisoned. After the reactor explodes above the planet causing damage, the fate of SG-1 and the crew of the Prometheus is in the hands of a once Goa'uld-controlled world that they're off to a rough start with.

In a firefight with Jaffa, Teal'c takes a staff blast to the gut. Without his symbiote, he cannot regenerate as he once did. Daniel feels that he cannot remember something important, so he goes searching through the logs for any sign of his lost knowledge. Teal'c expresses his feelings that the Tritonin has made him weak.

While exploring a crashed alien ship full of passengers in cryostasis, an alien force has downloaded a number of their consciousnesses into Daniel.

The documentarian still a thorn in their side, SGC encounters an unforeseen predicament. With half of SG-13 off-world engaging enemy Jaffa, SG teams 1, 5, and 7 go in as backup. In the midst of heavy fire, O'Neill takes a staff blast to the chest. Many deaths from the encounter hit SGC hard and Senator Kinsey orders a full investigation into the matter.

General O'Neill is still in the early days of commanding the SGC and faces a major problem when newly arrived Russian Col. Alexi Vaselov collapses in his quarters. Dr. Brightman's belief that Vaselof may be contagious seems correct when Daniel, who was with the Russian when he collapsed, apparently goes mad and tries to leave the base through the gate. O'Neill locks down the SGC but the problem isn't contagion: the essence of Anubis is alive and well and seeking a new host.

Dr. Lee is adapting a virtual reality chair for use as a training device. Teal'c thinks its current scenario is all too easy and agrees to work with them to make it more realistic. He enters the game scenario and is quickly "killed" at which point the chair shocks him. Lee says it must be part of its basic construct. As the scenario resets - it's an invasion of SGC by Goa'uld - Teal'c is repeatedly killed and shocked putting him in danger. The computer program is set up to learn after each scenario and the challenge for Teal'c increases at every turn. Daniel volunteers to enter the game as well to see if together they can find a way out.

Having obtained permission to live off the base, Teal'c rents an apartment, telling neighbors that he has recently arrived from Mozambique. He's under orders to keep a low profile but can't seem to help himself when it comes to helping his neighbors. He helps one who is about to be assaulted by three thugs, but it's his next-door neighbor who seems to need assistance. Krista is having problems with her boyfriend, Doug. Teal'c soon realizes that Doug is beating her and warns him that should he hurt her, Teal'c will kill him. It all becomes very difficult when Doug is found dead in Krista's apartment. Daniel Jackson soon after receives an offer - translate a Goa'uld text, and he will get ironclad evidence that Teal'c is innocent. Meanwhile, Carter is shocked when her boyfriend Pete Shanahan tells he asked for a transfer to the local police department and asks her to marry him.

When the Stargate gets beamed out of SGC in the middle of the night, Teal'c is stranded off-world. Dr. Jackson and Colonel Carter attempt to recover the gate.

With a new commander of the SGC comes a new leader of SG-1, Lt. Col. Cameron Mitchell, a former fighter pilot who flew an F-302 in the battle over Antarctica. However, he is deterred by the fact that all the other members of SG-1 are leaving for other ventures: Teal'c to manage the Jaffa Nation, Carter to Area 51 for alien R&D, and Dr. Jackson to Atlantis as an Ancient expert. Mitchell endeavors to keep the members of SG-1 for himself, but they are increasingly tough to convince.

While investigating the source of an addictive corn-like crop, SG-1 becomes involved in a firefight. They are forced to fall back to the gate, but as Daniel is dialing both the Stargate and the DHD are beamed away.

Based on the information Vala gave them, SG-1 travels to the planet where Merlin may have hidden his secret weapon to defeat ascended beings. There they find an appropriately medieval village and learn that Merlin kept a library there. The locals have never been inside owing to a curse on anyone who dares enter, but SG-1 finds a way in. Once inside, they find a secret chamber that may reveal the location of the weapon. The SGC, meanwhile, has located the Ori's Supergate. Sam's attempt to get control of it is too late, and four Ori ships make their way through. In the ensuing battle, much of Earth's fleet is destroyed, and the future of several SGC members is left in doubt.

Vala is kidnapped by agents of the Trust who are trying to find an ancient treasure when an accident causes Vala to forget who she is.

SG-1 blows up three transport ships in a row; Netan puts a price on their heads. General Landry grants the team members spare time on Earth. Daniel spends it researching in a library, where he meets a bounty hunter who tries to seduce him, then switches to her handgun... but is taken out by a bus. Sam gives a lecture on Air Force technological progress together with Dr. Bill Lee; a sniper nearly misses, but is taken out with an experimental weapon they'd brought along to demonstrate. Teal'c is injured by surprise at a Jaffa camp and successfully traps the killer to try again. Cam goes to his Kansas high school reunion and Vala succeeds in making him bring her along, pretending to be his accountant and partner. His still sexy former flame he'd believed out of his reach, Amy Vandenberg, is initially scared off by Vala, but, divorced and interested, explains she still has a secret crush on him. Alien bounty hunter Odai Ventrell assumes numerous classmates' appearances to kill him. Vala's failed rescue gets them both captured publicly, so he threatens to kill off reunion guests unless the other SG-1 members take their place, but they trick him using Chimera technology; they hope Netan's failure to eliminate them will rekindle the power struggle and Odai reacts surprisingly.