A psychotic patient threatens Abby. Dr. Weaver suspects a woman poisoned her own baby. Dr. Romano continues to make rash judgments.

Dr. Carter tries to prevent a grieving gang member from going after vengeance. Dr. Kovac races against time to save a Croatian boy's life. A baseball player gets treatment for a heart problem.

It's Greg Pratt's last shift at County General and he treats a number of cases that were started by John Carter on the day shift. They treat a 12 year-old near drowning victim who has little chance of recovery; a Buddhist nun who has a special gift of seeing another's inner self; a woman who is convinced that the day's solar eclipse signals the end of the world; a drug addict who scams both of them for pain medication; and a pregnant woman who had her baby torn out of her womb. Dr. Romano has his re-attached arm amputated. Carter receives a call from Luka Kovac asking if he can come to the Congo and help out. Abby is none too pleased. Meanwhile, Doc Magoo's burns to the ground.

Carter returns from Africa full of surprises including a new love, Makemba ("Kem"). Pratt accidentally breaks a patient's neck while doing an unsupervised intubation. A whole nursing shift cannot go home until they find one missing Valium.