A shady homeless man, named Lou, comes to the station thinking he's a werewolf and demands to be locked up into a cell before he kills someone when the night comes. However, things take a turn when Kelly investigates Lou when he may be a witness in the murder of a nine-year-old immigrant boy. Meanwhile, Sipowicz is visited by his long-estranged son, Andy Sipowicz, Jr. with his fiancée, Patty Constance, an older woman who Sipowicz discovers that she has been cheating on Andy Jr. Elsewhere, Giardella is killed in his hotel room by a Mafia button man dressed as a window washer before he can testify to a grand jury against his superiors and Laura finds herself the only witness to the murder.

The mob hit man who killed Giardella and who Laura can identify, is trapped on the roof of the building with a hostage. Martinez works on his first detectives case, which involves a fake ATM machine taking peoples money. Meanwhile, Fancy and his wife prepare to face a court date when a foster child they've been caring for is ordered back into custody of the real mother who's just been released from a drug rehab program. Sipowicz and Kelly investigate a shooting of mobster Tommy Linardi, whom had taken over the late Angelo Marino's organization, in which turns up a notebook that Marino kept which has Janice's name in it. Janice asks Kelly for help who decides to steal the notebook to protect her from further investigation to Marino's murder, while Fancy again locks horns with Inspector Lastarza over the handling of the case.