Meredith and Derek find that "happily ever after" isn't as easy as they hoped, Cristina finds interest in a military doctor, and the Chief is surprised to hear that Seattle Grace is no longer ranked as a top-tier teaching hospital.

As a group of best friends deal with the aftermath of their car crash, Dr. Torres takes the lead on a groundbreaking course of treatment for one of the patients. Meanwhile, Major Hunt starts to irritate other attendings with his presence in the hospital.

Bailey's dream of a domino surgery crumbles when one of the donors learns of her husband's affair. Meredith is insulted when she gets no credit for the procedure she and Derek worked on together.

The new trauma surgeon shocks everyone with his methods, Bailey is asked to save a girl with an inoperable tumor, and Callie's not sure what she wants.

The residents and interns squabbling over procedures upsets Dr. Hunt, Erica discovers what happened to the heart she lost, and Derek asks Sloan to break out the McSteamy to distract Yang.

Izzie wrestles with her ghost, Torres uses a ground-breaking procedure to get her mind off of Hahn, and the interns continue teaching themselves spurred on by a new cohort.

Sadie manipulates the interns into performing a procedure that goes horribly wrong, Izzie's ghost refuses to leave, and Mark bonds with a girl who's taken responsibility for her sleep-walking father.

The residents make their cases for the solo surgery, Sadie chafes at her restrictions, and Sloan battles his desires.

Derek has trouble with objectivity concerning his death row patient, Cristina and Meredith continue their feud, Izzie confides her problem to Alex, and the Chief faces what's become of his life's work.

Derek's mother visits, the death row patient starts angling for death in the hospital, Izzie craves more in her relationships, and Jackson's need for organs becomes critical.

Meredith and Miranda each cross a line, William Dunn regrets his decision and Izzie finally confronts what Denny's appearance means.

Cristina carries on an intense flirtation with Owen, Derek gets advice from everyone on how to propose, Izzie gets some tests done, and Bailey's promotion may stand in the way of a new career possibility.

Owen runs into someone very special from his past. Izzie employs her fellow doctors in a medical game made to help teach the interns. Naomi, Sam and Addison rush Archer to Seattle Grace and meet with Derek and Mark to save his life.

Addison and Derek differ on the treatment plan for their patient, Cristina discovers malpractice in high places, Izzie gets bad news, and Mark spectacularly mistimes his confession.

Derek's malpractice deposition reveals an unhappy statistic, the interns finally diagnose 'Patient X', Karev stands up to two attendings to save a band geek, and when Webber shuts Miranda out completely she makes a call.

Sloane's facial transplant fades to the background as the interns begin squabbling, Bailey's attempts to reach Derek unexpectedly clear surgeons from the hospital, and Cristina juggles her first solo surgery with treating a resistant Izzie.

Owen's PTSD endangers Cristina, Izzie's illness leaves the residents dealing with guilt and anger - at her expense, and Derek's fear causes him to persevere for Meredith's answer.

Izzie bites off more than she can chew on her first day of chemotherapy, Mark and Derek are forced to work on the same patient, Meredith's plans for a simple wedding take a turn, and Karev finds himself split between worry over Izzie and excelling as a resident.

Izzie's mother comes to town, a little girl shoots her father triggering a conflict between Meredith and the chief, Thatcher reappears, and Callie gets her first taste of life without her trust fund.

A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey searching for the cause, and the results will change the outcome of the day.

Izzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief tries to lure Bailey back to general surgery with a new toy, and Mark shifts into high gear with major life changes.

Izzie's memory problems panic Alex, the team takes care of a John Doe who was hit by a bus, Bailey rethinks her pediatrics fellowship, and the hospital endures losses.

Covering days one through 13, everyone at Seattle Grace fights to save Izzie and George's lives and then deals with the aftermath. Elsewhere, Hunt treats a double amputation, and Arizona has a teen with painful growth spurts.

During days 20 through 40 the staff continues toward acceptance. Meanwhile, Arizona takes a manipulative step to diagnose her pain patient and Hunt's amputee patient sinks into a deep depression.

As hospital personnel jockey for notice to keep from being fired, Izzie returns to surgery early and Bailey's triple aneurysm patient refuses her procedure because of her schizophrenic son.

Thatcher is hospitalized with liver failure, and Meredith fights anger and guilt while deciding her responsibility. Sloan treats an octogenarian who wants an implant. Izzie's interference in Hunt's cancer case may have deadly consequences.

As Mercy West merges with Seattle Grace, battle lines are drawn between the two hospital's residents over the patients.

After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace residents defend their actions in an effort to save their jobs.

When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.

A generous donation is offered to Seattle Grace by the parents of Arizona's 10-year-old patient. When his condition worsens, however, she finds herself with a conflict of interest. Meanwhile, Cristina tests her boundaries with Owen at the hospital and, adding insult to injury, Alex is left with all of Izzie's hospital bills to contend with.

When Owen recruits his fellow Iraqi War vet, Dr. Teddy Altman, as the new cardiothoracic surgeon, Cristina questions Teddy's abilities in the OR and the nature of their past relationship. Meanwhile Izzie returns to Seattle Grace with her high school mentor seeking treatment for his dementia, and the stress of Richard's responsibilities, post-merger, are taking their toll.

As Thanksgiving, Christmas and New Year's pass, Miranda is visited by her father, William, who disapproves of her choices in life; meanwhile, Mark and Lexie must cope with the shocking arrival of a woman from his past, and Thatcher Grey questions the Chief's recent behavior as Meredith comes to his defense.

Mark flies Addison to Seattle to help with a difficult procedure on his pregnant daughter, Sloan. Owen questions Teddy's motives when she assigns Cristina the lead on a complicated surgery, and Derek's suspicions are raised when the Chief recruits Meredith to assist with a high profile operation.

After learning of Richard's drinking problem, Derek confronts him for the sake of his friend and the hospital, Izzie returns, hoping to reconcile with Alex, and tensions run high between Teddy, Cristina and Owen in the aftermath of Cristina's startling confession.

An intra-operative crisis casts a shadow over Derek's first day as interim chief, Owen's influence worries Cristina, Karev's first pediatric surgery case turns out to be more than babysitting and Webber resents the decision he must make.

It's Valentine's Day and the doctors must treat dozens of injured people after the roof collapses at a popular romantic restaurant; Derek tries to manage his busy schedule as Chief of Surgery; Meredith wrestles with her new duties as the Chief's wife; and Mark and Callie team up to convince Sloane to do the right thing for her baby.

In his new role as Chief, Derek restores the hospital lecture series, and several attendings present to the group pivotal surgical cases from their pasts: Bailey reflects on how shy she was as an intern until getting advice from Webber, Callie looks back on a polio case, and Richard recalls a case in which he and Ellis worked on a patient diagnosed with AIDS, known in 1982 as GRID.

When Avery's grandfather comes to the ER, Webber's wish for a stress-free first day back is lost after the surgeon requests an awake surgery. Elsewhere, Cristina and Teddy attempt a hand-me-down lung transplant for a cancer survivor.

A patient who needs an extremely difficult surgery comes to Seattle Grace, and it's Richard and Owen who vie for the opportunity to tackle it. But the decision lies in the hands of Derek, who deems that Owen should take on the surgery, leaving Richard bitter. Meanwhile, Bailey deals with her own personal struggles when she nervously prepares for another date with Ben.

When Teddy's patient seeks to end treatment and her life, she turns to Hunt for help. The situation triggers Hunt's memories of his life at war and his past relationship with Teddy. Meanwhile, Callie and Arizona have a difference in opinion on what their future holds, and Richard tries to adjust to his role as a surgeon.

Alex' brother Aaron comes to Seattle with a hernia and needs a pro bono operation. Having children is on everyone's minds and tensions are high because of it.

Sloan returns to Mark's apartment just as she's going into labor. Teddy, Mark and the still-fighting Callie and Arizona are there to help with the birth and to get Mark through his grandson's pending adoption. Meanwhile Teddy sees Derek's invitation to illustrious cardiothoracic surgeon Tom Evans' as a threat to her future employment at the hospital, and the team work on a crab boat captain who has been stabbed with a giant shark hook.

Bailey preps the team with mandatory sensitivity training prior to admitting a 700-pound patient with compounded medical issues, and the case proves to be challenging. Meanwhile Derek has to come face to face with a former patient's husband in a wrongful death deposition, and spending time with a heart patient's daughter opens up some old wounds for Cristina.

An elderly patient admitted into the E.R. for a heart condition sees a familiar face, a long lost love who happens to be in the E.R. as well for a fractured arm, and the staff find themselves caught up in their love story. Meanwhile, Karev treats a troubled teenage patient whose parents brought her in for schizophrenia, and Meredith can't help but tell Cristina about her suspicions of Owen -- which inevitably messes with Cristina's head.

Seattle Grace Hospital is hit with a crisis like no other in its history.

Cristina and Meredith's surgical skills are put to the ultimate test.

Dereks near death experience results in reckless behaviour; Meredith has trouble getting cleared for surgery in the wake of the shooting and Cristina & Owen take their relationship to the next level.

After weeks of concealing the fact she was pregnant and miscarried, Meredith at last tells Derek and is finally cleared to return to her surgical duties in the wake of the hospital shooting spree; Cristina experiences post-traumatic stress disorder in the midst of an operation; and Bailey refuses to let Alex operate until he agrees to have the bullet in his chest removed.

When Derek receives an unexpected and unwelcome visit from his estranged sister, Amelia, issues between the siblings -- both past and present -- come to the surface; the Chief tries to help Alex when he notices that he's refusing to use the elevators after his near-fatal shooting; and Meredith and Derek continue their efforts to ease Cristina back into surgery after her post-traumatic stress.

Things are hostile on all fronts when a visit to the obstetrician results in some disturbing news for Meredith and Derek and Lexie loses it when she notices Meredith and April getting closer. Meanwhile, a car crash brings in multiple traumas and Jackson tries using his physical attributes to get ahead in the operating room, while Cristina's self-doubt carries outside of the hospital and into her house-hunting with Owen.

As part of their training, the Chief puts Seattle Grace's residents -- including Meredith, Cristina, April and Jackson -- in charge; meanwhile, Derek, Callie, Owen and the other attending surgeons compete for a million-dollar grant.

A documentary film crew visits the hospital six months after the shooting to document the road to recovery for doctors and patients. The camera lenses follow Derek, Owen, Mark & Callie as they ambitiously perform a rare arm transplant surgery, Meredith helps Cristina put on a brave face for the cameras, and Bailey's patient, Mary, returns for her surgery -- which marks the first time they've all seen of each other since that fateful day.

The residents are pushed to their limits when Owen puts them through a rigorous trauma certification drill; meanwhile, Cristina is also tested when left alone to monitor a very ill lung transplant patient.

Top security measures go into place as a team of doctors, led by the Chief, try to save the life of a major political figure from the Middle East. Meanwhile Cristina decides to finally decorate her new place and throw a housewarming party, and Alex shows up late from a weekend getaway to his first day of rounds with the new Pediatrics Attending, Dr. Robert Stark.

Derek lands the grant he needs for his clinical trial and all the attendings take him out to Joe's Bar to celebrate, but they get a surprise when they see someone they know already at the bar. Meanwhile, Meredith and Alex have to fend for themselves during the night shift with a nine-year-old patient who's experiencing post-surgical complications and his very pushy mother.

Despite Meredith's objections to the idea, a concerned Derek takes Cristina on a fishing trip in order to get away from it all, while Teddy, feeling directionless without Cristina, directs all of her efforts and compassion towards a dying patient who lacks the proper insurance to seek medical treatment.

News of the incoming mass causalities after a gunman opens fire at a local college hits the staff hard when they must spring into action, even while their own wounds are still fresh; and Arizona does not receive a warm welcome home at the hospital.

Arizona seeks Mark's advice as she tries to reconcile with Callie, who has big news of her own; Teddy must make a key decision for Henry during his surgery; and on the same day the residents receive a new crop of interns, the Chief announces he is looking for a new Chief Resident.

Meredith feels left out when Derek breaks ground on his clinical trial; Bailey's new idea does not go over well with the chief; Callie irritates her new obstetrician.

Le père de Lexie revient à l'hopital avec des douleurs abdominales et une jeune fiancée. Alex se prend la tête avec la nouvelle obstétricienne. Mark fait du chantage à Jackson pour en apprendre sur Lexie.

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour's time when she steps up to run the ER for a night; meanwhile, Bailey sneaks off with Eli and gets into a little mischief, and everyone is surprised when the Chief's wife, Adele, shows up as one of the ER patients.

Meredith must choose between her fertility treatments and her eyesight when she begins having trouble seeing, Mark makes it clear to Callie and Arizona that he takes his role as father-to-be very seriously, and April discovers there's more to Dr. Stark than first appears.

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer's trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of the kind of baby shower Callie wants, Teddy is freaked out when Henry has another health complication -- leaving them both a little exposed -- and the competitiveness amongst the residents for the Chief Resident position is amplified when Richard receives the green light for his diabetes clinical trial.

In a series first, the music that has been at the heart of the show and been beloved by fans comes to life for Grey's Anatomy: The Music Event. A cataclysmic event rattles the doctors of Seattle Grace to the core, as Callie, on the verge of an enormous life-changing moment with Arizona, envisions her hospital and friends as it has never-been-seen before. "Chasing Cars" (Snow Patrol), "How to Save a Life" (The Fray) and "The Story" (Brandi Carlile) are among the songs performed by the cast.

Everyone pulls together to help Callie and baby Sofia on their painstaking journeys to recovery in hopes of allowing mother and baby to finally meet; the sudden death of a clinical trial patient has Derek proceeding with more caution while Meredith makes a calculated and risky move; Alex treats a cranky old rich woman dying of cancer and gets an idea for a grandiose endeavor that is sure to get him the Chief Resident spot; and Teddy is pleasantly surprised by the return of a familiar face.

As Callie and Arizona's wedding approaches, the couple quickly realize that the day they've been looking forward to is not turning out the way they'd envisioned. Meanwhile Alex continues to make the other residents jealous as he appears to be the top contender for Chief Resident, Meredith and Derek make a decision that will change their lives forever, and Dr. Perkins presents Teddy with a very tempting proposition.

As the official Chief Resident interviews begin, everyone steps up their game in the hopes of impressing Owen. Meanwhile, Meredith anxiously prepares for her first interview with the social worker and Cristina fights for a shot in the operating room.

While Meredith faces the consequences of tampering with the trial Cristina and Owen fight over an unexpected pregnancy.

Meredith faces the repercussions of messing with the medical trial.

News of Meredith and Derek's unsteady relationship raises a red flag for Zola's adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out Meredith; and Cristina makes a tough decision regarding her unexpected pregnancy. Also, Chief Webber brings Henry in for a last minute surgery, alarming Teddy.

The chief makes a decision that shocks everyone at Seattle Grace.

A stampede at a comic book convention leads to an influx of patients.

The residents try to impress Jackson's mother, Catherine Avery.

Lexie tries to get Derek interested in a patient's rare brain tumor.

Owen organizes a baseball game against Seattle Presbyterian.

Jackson's suspicions about Mark and Lexie interfere with work.

Teddy is called away on another case, as Henry is brought in for surgery.

Teddy asks Cristina to help with an OR patient.

The doctors form two teams to operate on conjoined twins.

While Derek prepares to operate on a tumor deemed entirely inoperable, Hunt pressures Meredith to declare a specialty. As Cristina and Teddy try to steal a prized cardio surgery, the doctors celebrate Richard's 10,000th surgery.

Meredith dreams of what her life would have been.

On Valentine's Day Lexie volunteers to watch Zola for Meredith and Derek; Callie plans an evening for Arizona; and Ben shows Bailey how much he cares. Meanwhile, Christina and Owen drift farther apart despite the fact that he saves her when a car crashes into the hospital. Meredith and Bailey treat a woman who has headaches and seizures. Webber and Lexie treat a man who was hit by a car during a fight with his girlfriend. Alex treats a 10-year-old girl who has a severe reaction to peanuts when her boyfriend gives her a Valentine's Day gift.

In a final attempt to save Erica's life, Amelia arrives at Seattle Grace to beg Derek for help with the gliosarcoma case; Cristina and Owen engage in heated arguments during marriage counseling; Alex realizes that in order to be a good doctor, he'll need to improve his people skills; and Meredith is given a chance to shine when a man enters the ER after getting his hand stuck in meat grinder. Meanwhile, the residents continue to study for their upcoming oral boards.

As Adele's condition continues to deteriorate, Richard considers altering their living situation; an explosion at a local coffee shop results in a busy day in the ER for the doctors; Callie takes Meredith under her wing by helping her study for her boards; Lexie joins Arizona and Alex in peds, as they continue to care for intern Morgan's premature son; and when Jackson snaps at a patient, Mark encourages him to find ways to relieve his stress. Meanwhile, Cristina lets her suspicions get the best of her.

Derek encourages a hesitant Meredith to work with him again in neurology. When she complies, she listens as Derek is talking to a patient, who excitedly tells him about how she passed out in the middle of a big job interview. They're going to remove a cyst that's causing seizures. There is also a benign tumor that they aren't going to remove. Just as the procedure is past the opening skull stage, Derek is called to another OR where Morgan's baby is suffering from a brain bleed. He tells Lexi and Meredith to carry on. A slight bleed leads to another chunk of skull being removed. This opens up sight of the benign tumor. They decide to remove it because access is already present. Derek is incensed when he returns. It wasn't in the plan. When the patient awakes, she is unable to speak. Her parents threaten to sue. Jackson's mother, Catherine Avery, returns to Seattle Grace with a urology fellow, to replace a faulty bladder with one that Richard and Miranda have grown in the lab. During the procedure, Catherine develops an interest in Richard, becoming quite flirtatious. The fellow, Dr. Mara Keaton, was brought to be a spy for Catherine about how her son is doing. Jackson is forced to take her on a hospital tour. He is instantly suspicious of her motives and calls her on it. She admits that she is supposed to gather information on him. In turn, he advises Mara on how she can assert herself and gain his mother's respect. They try it out, defying her intent to take them to an awards banquet. The two of them trip off to find an empty on call room to get to know each other better. Richard is asked to the award banquet but turns her down at the last minute. Cristina becomes increasingly suspicious of Owen's every move. She finally corners nurse Emily, her prime suspect, and asks her point blank about sleeping with Owen. Emily says no. She uses a bit of flirting to get through long shifts. When Christina faces Owen, he admits he has been unfaithful to her. Alex has been working continuously to save Morgan's preemie. Callie watches Alex and Morgan work together and sees that Morgan is falling for him. He denies it. But when Morgan has her picture taken with him and the baby, you can see it in her body language.

A pet lion on the loose gives the hospital some fierce injuries to deal with. Meanwhile, Cristina continues to ignore Owen, Lexie reconsiders her feelings for Mark, Callie has to face Arizona's romantic past with other hospital staff, and Alex starts to feel uncomfortable about his relationship with Morgan.

Grey, Bailey, and Webber work on a multi-organ transplant but run into some barriers when Dr. Sloan, the temporary Chief, orders them to cancel the surgery. Meanwhile, Cristina and Owen spend the day at home, working through their marital problems.

While the hospital becomes the center of attention as the victim of a famous kidnapping case is brought to the hospital, the fifth years take their placement interviews. Meanwhile, Adele Webber's memory continues to deteriorate, forcing Richard to reconsider their relationship.

As the fifth-years head off to San Francisco to take the most important exam of their lives there are some surprises along the way; Owen and Teddy continue to fight back at the hospital; Mark and Lexie reconnect; and Tommy's condition worsens.

Six hours after their oral boards, the fifth years relive their answers and worry about their chances. Back at the hospital, Bailey has to woo potential candidates for the hospital and Mark is startled when Julia makes a proposal about their future.

Before the Seattle Grace doctors head to Boise to take part in an operation on conjoined twins, the Attendings pressure the 5th years for final decisions on their posts next year. Meanwhile, Arizona must face the reality of her friend's condition and Ben tries to get Bailey to go on a special lunch date.

As Meredith, Cristina, Derek, Mark, Lexie, and Arizona face the aftermath of their accident, the doctors back at the hospital face the future that seems to be taking them all in different directions.

Months after the plane crash, the doctors at Seattle continue to try and find a new sense of normalcy. With a new set of interns to put through the ringer, the new fellows and attendings get used to their roles while Cristina adjusts to her new life in Minnesota. But the life of one doctor hangs in the balance and it's clear that Seattle Grace Mercy West is not the same.

Each of the doctors involved in the crash experiences flashbacks that take them back to their time of rescue and explain how they got to where they are now.

The survivors of the crash are presented with a settlement offer, which forces them to choose between putting the incident behind them or investigate the true cause. Meanwhile various events occur: Jackson and April struggle to work with each other, Bailey is annoyed by the new attendings' behaviors, Callie struggles to communicate with Arizona and Cristina learns to work with her new colleagues in Minnesota.

As Cristina begins to make new "friends" in Minnesota, Meredith struggles with whether or not to tell Derek about an extremely rare case she is working on. Meanwhile, Arizona begins work with her new prosthetist and tensions flare around work when Jackson's mother comes into town.

Split between Meredith in Seattle and Cristina in Minnesota, this episode shows each surgeon tackling an incredibly challenging surgery. Meredith must juggle work and parental obligations while Cristina is caught between Dr. Thomas and Dr. Parker.

Cristina's return to Seattle proves to be awkward when she and Owen must face each other again. Meanwhile, Jackson and April continue to try and negotiate their relationship, Jo deals with a perplexing case, and Bailey attempts to get Arizona into the hospital. Then, the survivors of the crash are shocked with new information about the cause of the crash.

It's Arizona's first day back at work and Callie tries to keep things as normal as possible for her. Meanwhile, Bailey argues with Ben over wedding plans and Cristina and Owen continue to struggle with their relationship while Owen faces his first set of meetings about the plane crash.

In an intern-centered episode, Jo and Alex work closely together and Jo discovers she has a certain image. Meanwhile, Meredith's intern is forced to find a donor nerve for Derek's hand and Cristina pits two of her interns against one another in competition for time in the OR.

As a jittery Bailey prepares for her wedding, Meredith and Derek disagree on whether or not to go through with the nerve transplant from Lizzie. Then, Cristina learns of the real reason behind Owen's plea for a divorce and Jo finds herself in trouble when she accuses Alex of mishandling her training. Then, a last minute emergency changes everything.

As Bailey puts her wedding on hold to tend to Adele, a biker gang floods the hospital with injuries for all the other doctors to tend to. Meanwhile, Cristina and Owen make a final decision about the divorce and Callie and Arizona try to reconnect.

The survivors receive a final verdict about the plane crash. Meanwhile, Derek continues to undergo rehabilitation on his hand, Cristina and Owen enjoy their new relationship with each other and Richard tried to avoid Catherine's advances.

Arizona is grappling with the pain of Phantom Limb when a consultant arrives at the hospital to begin investigations. While Derek embarks on his first major surgery, Meredith faces her biggest fear as she experiences pregnancy mood swings.

While Derek and April try and find a way to save the ER, Cristina and Leah struggle to keep a patient alive while respecting his wishes. Alana is pulled into a surgery with Owen that may change the way she views the hospital's ER.

Alex and Jackson are pitted against each other to become the next "face" of Seattle Grace while they work on a sex reassignment surgery for a transgender teen. Then, April brings in an emergency trauma case which requires the help and discretion of many of the doctors. Meanwhile, Callie and Richard visit a recently revitalized hospital to understand what they are all in for.

As the hospital inches closer to finding a buyer, many of the doctors don't like the new changes being made, causing the crash survivors to consider a crazy idea. Meanwhile, April's relationship with Matthew progresses and she asks Jackson for advice.

The crash survivors race against the clock to find a buyer for the hospital before Pegasus closes in. Meanwhile, the interns and other doctors at SGMW plan for what they believe will be their imminent departure while Jackson's mother continues to try to convince him to move to Boston.

The transition to new management has the doctors at each others throats. Matters become worse when Owen quits, leaving the OR board in complete disarray.

With the new Grey Sloan Memorial Hospital up and running smoothly, everyone is happy about the new changes. Meredith worries about the health of her baby while Bailey tries to get the board members to fund her new plan for genome mapping. Meanwhile, Arizona's new prosthetic gives her the confidence to reignite her relationship with Callie. With the help of a patient, Alex pulls some pranks on Jo's new boyfriend and Cristina tries to get involved in groundbreaking cardio research.

When a giant gas tanker explodes on a highway, a couple of parents are admitted to the hospital while Owen looks after their son. Matthew is caught in the explosion and is admitted to the hospital while a single mother fights to find out what mysterious illness is plaguing her son.

A couple of Syrian doctors arrive at Grey Sloan Memorial to learn field techniques for war zones. Then, when a series of patients return with post-op infections, one doctor's work falls under suspicion.

At Jackson's request, the CDC arrives at the hospital to begin an investigation surrounding Bailey's patients. April blames Jackson for her breakup with Matthew and Alex tries to be nice to Jason. Owen continues to get closer to Ethan as his dad's health remains uncertain.

A magician's assistant arrives at the hospital with a severe injury that has all the general surgeons involved, except for Bailey who is ignoring all of the attendings. As Cristina searches for a way to wake his father up, Ethan has a medical emergency of his own. Alex tries to avoid Jo at the hospital and a new cranial-facial specialist flirts with Arizona.

With a major storm rolling in, the hospital is chaotic. When Jason comes into the hospital in critical condition, Alex does everything he can to protect Jo. With Meredith's due date just weeks away, Derek urges her to slow down.

As Seattle is plunged into a major storm, Meredith goes into labour. When the hospital loses power, her doctor and all the others are forced to work in the dark. Cristina must perform surgery in almost complete darkness while Arizona, Alex, and Lauren must ward off terrified parents. Then, just outside the hospital, a school bus full of people crashes and flips over, forcing several doctors to rescue its passengers. Cristina finally confronts Owen on his desire to have kids.

Following the storm, a mudslide injures first responders and citizens.

Callie makes a decision about her relationship.

Derek and Meredith adjust to life at home with their newborn.

The doctors put together a fundraising gala.

Meredith struggles to balance her roles as a surgeon and a mother.

Callie and Derek collaborate on a brain mapping project.

Costumed patients create a challenge for the doctors; Derek and Ben work on a new surgical technique; Richard asks a resident to perform his next surgery, angering Bailey.

A betrayal intensifies the issues between Cristina and Meredith; Matthew and April make a decision about their relationship; Bailey faces difficulties with Ben's return.

Callie's career is on the line when she is being sued for negligence after an operation on a star athlete goes horribly wrong.

Ben worries that an innocent conversation with Derek could end up causing problems for Bailey; Cristina turns to Shane as tension with Meredith increases; April's upcoming wedding creates an uncomfortable situation for Stephanie and Jackson.

April's visiting sisters get on her nerves; when Matthew and Jackson witness an accident, they must work together; Callie and Arizona work on their relationship.

Meredith and Cristina bicker about their careers; Bailey talks to Ben about him moving back to Seattle; Shane puts himself in a risky situation; Derek receives a life-changing phone call.

The doctors face the consequences of the events that took place at April's wedding. Meredith feels betrayed when Derek goes back on a promise, Alex is furious after returning to the hospital and hearing the news about his father, and Arizona and Callie decide whether or not to move forward together. Meanwhile, Bailey realizes she was wrong about the motive behind Ben's decision to move back to Seattle.

Couples panic when the hospital announces a nonfraternization policy; Owen and Emma discuss the future; Meredith and Cristina have some girl time; Richard asks the residents for help with a rare cancer case.

Arizona's bad day escalates when she advises a patient on a potential double amputation; Derek breaks a promise; Stephanie and Jo find an abandoned baby; the nonfraternization rule leads to a suspension.

Richard is given a rare case for his birthday, given by Bailey. Catherine Avery returns to try to talk sense into Jackson for marrying April.

Follows Christina's life as she wonders how her life would take shape based on a single decision.

The doctors of Grey Sloan Memorial Hospital succumb to an infection that spreads like wildfire. Cristina deals with a complex case involving siblings and Alex begins to consider his future in the hospital.

Meredith and Bailey tackle jealousy as Cristina receives an early morning phone call that might change her life; Callie comes to a shocking realization and Alex makes a decision.

Callie and Arizona discuss having another baby, Derek has a hard time juggling work and family, Jackson and April have their first big fight and Christina attends the Harper Avery Award Ceremony. But is she going to win?

Derek's sister Amelia comes for a visit; Alex confronts Arizona and the rest of the hospital about his decision; Dr Webber finds out the truth about Harper Avery award from Catherine.

The doctors work together to operate on two sisters joined at the head; Cristina travels to Zurich where she deals with a blast from her past; Richard voices his concern over the hospital's allegiance with the Harper Avery Foundation.

While Bailey faces dire consequences for her reckless behavior, Cristina interviews candidates for Dr. Russell's replacement. Alex returns with a motive, disappointment hits Callie and Derek brings forth a shocking proposal to Meredith.

Cristina must head to Zurich soon but she is unprepared to leave behind her life in Seattle. Fear runs amok throughout the hospital as an explosion in a shopping mall results in a mass casualty situation.

Callie and Arizona have to make a choice regarding surrogacy while the board has to decide whether to give Cristina's seat on the board to Alex or Bailey. Amelia overhears the truth about Maggie Pierce.

In this Maggie-centric episode, she continues to try to make a positive impression at the hospital but finds herself in extremely unfortunate situations. Meanwhile, Richard continues to hold onto his secret and the doctors work with a dying woman who is being kept alive by her daughter.

Owen introduces Callie to the Veterans Hospital patients in hopes that she will help them with her robotic limb lab, Jo becomes jealous of Alex and Meredith's friendship, and Maggie continues to confide in Richard. Meanwhile, Alex and Bailey prepare to go in front of the board.

Secrets from Ellis Grey's past come to light when Meredith watches old videos and reads through her mother's journals. Meanwhile, Maggie rocks the hospital with an unexpected announcement; Alex gets new responsibilities and Callie focuses her attention on the Veterans' project.

Callie and Arizona examine their marital problems and what's contributed to them. Meanwhile, Callie devotes herself to the veterans' project; Arizona strives to impress Dr. Herman; and Richard seeks guidance from Bailey.

A woman comes in badly hurt from a car jack and Owen pays some extra attention when she is found to have served in the military. Derek desperately tries to organize a dinner binding together Meredith's complicated family but is fought from every angle. Meanwhile April reacts strongly to the arrival of her mother and Arizona is fighting hard to manage under the pressure from her new "boss".

Arizona has to take care of one of Herman's patients. Everybody finds out Amelia was a drug addict and Derek lets her down. Jo has her first solo surgery. Maggie is invited to Ellis' house and Arizona decides to move in with Alex.

Pierce and Grey disagree with Derek about the best way to approach a patient's case, which lead the couple to a very big argument. Meanwhile Callie feels responsible for one of her veterans when he is pushed too far and a doctor's routine procedure shows devastating results.

Meredith keeps herself busy while Derek prepares for his move; Jackson and April get difficult news; Arizona and Amelia talk about how best to approach Dr. Herman.

April stays positive as tests are run on her baby; Dr. Herman plans a crash course in fetal surgery; Callie and Owen encourage each other to return to the dating scene; Bailey, Meredith and Maggie try to learn more about a patient's tumor.

Meredith tries to find a sitter so she can go visit Derek, Amelia and Stephanie work together on a case.

Maggie gets upset when Meredith dodges her questions about DC; Bailey and Ben become concerned about Ben's brother after he is admitted to the hospital, and Dr. Herman starts to warm up to Arizona. Meanwhile, Richard begins to feels manipulated by Catherine.

The hospital doctors become fascinated with Dr. Herman's case when Amelia gives a lecture detailing the intricacies of the surgery. Arizona and Herman continue to bond over the amount of cases they are trying to complete before the big surgery. Meanwhile, Bailey brings them a case of a pregnant woman who is close to her heart.

The moment of truth has arrived. Amelia begins the daunting surgery to remove Dr. Herman's tumor. Meanwhile, Arizona takes the lead on a case that means a lot to Dr. Bailey.

An earthquake leaves Maggie trapped in an elevator and threatens Meredith's streak of successful surgeries; Owen gives medical advice over the phone; Ben opens up Jackson.

A man with Alzheimer's crashes into a pregnant woman; Meredith worries about Derek cheating on her and the state of their marriage.

Rattled by recent events, Meredith tries to decide what to do about Derek; Owen is stunned when his mother is admitted to the hospital.

A group of children visit the hospital on a field trip and observe two injured cops rushed into the emergency room. Meanwhile, Stephanie develops a crush on one of the chaperones, and Amelia's forced to confront her feelings about Owen.

Upon realizing that Owen and Amelia have been seeing each other behind her back, Meredith comes down hard on her sister-in-law causing Amelia to rethink things. Meanwhile, Catherine springs into action when a man is brought into the hospital after his wife seeks revenge on his cheating ways.

A small plane crash results in multiple casualties, bringing back terrible memories.

Derek witnesses a horrible car crash and jumps in to save lives.

Jackson struggles to understand April's decision; Ben & Bailey discuss their future; a patient revisits Callie; Amelia tries to deal with her past.

Months after Derek's funeral, Amelia struggles with her emotions; April plans on returning; and a part of Derek continues to grow in Meredith's life.

The doctors must set their emotions aside and focus on a catastrophe.

As the doctors continue to tackle an unfathomable crisis, they are reminded of what is important and brought closer together.

The doctors from Grey Sloan Memorial Hospital spring into action to save the lives of two girls with a powerful story. Meanwhile, Meredith tries to cope with the fact that Amelia is now living with her, and Jackson prepares for April's return back to Seattle.

The pressure is on as a determined Bailey tackles her first day as Chief; meanwhile, April's marriage is in jeopardy and she finds herself unable to address her problems; Meredith struggles to juggle all her responsibilities and Amelia works to define her relationship with Owen.

When Maggie gets an invitation to her ex-boyfriend's wedding, she starts to reevaluate her choices.

Owen suggests the interns learn about breaking bad news to patients' families.

Maggie leaves her dinner party and races to the hospital, so April takes over the cooking duties in an attempt to avoid Jackson. Meanwhile, Arizona is extremely anxious about meeting Callie's new girlfriend, who happens to be a familiar face in Meredith's life.

Penny's first day gets off to a rocky start. April brings a young patient from overseas with tumors on his hands. Jo and Stephanie's feud continues.

A high-stakes case is tackled by a team of doctors, and the atmosphere grows tense. Meanwhile, Bailey pressures Ben to evict their roommate; and Arizona enthusiastically reenters the dating scene with a new wingman.

As the rumor mill around the hospital continues to spiral out of control, Grey Sloan Memorial is flooded with injured firefighters from a nearby wildfire. Maggie struggles to keep things with Andrew professional at work; meanwhile, Jo questions Alex's priorities. Also, Alex decides to make a big step in his life.

Meredith is attacked by a patient, and Penny finds her injured. The staff of Grey Sloan Memorial is standing by Meredith trying to save her life.

As the hospital deals with Meredith's trauma, Callie and Maggie perform a risky, experimental surgery on Alex's 15-year-old patient against his professional opinion. Meanwhile, Owen and Nathan are still at odds with each other, and Maggie and Andrew's relationship continues to develop.

Flashbacks reveal the evolution of April and Jackson's relationship, beginning with their initial meeting, and the years-long process of one of Jackson's patients. Also, April finds out something life changing.

A patient from Meredith's first surgery as an intern is re-admitted to the hospital with an aneurysm; Maggie thinks Richard knows about her relationship with Andrew; Arizona considers dating again.

Meredith, Jo, Bailey, Callie and Jackson head to a Veterans hospital for an spectacular yet unusual surgery. Meanwhile, a group of snobby cheerleaders come into the ER and Warren makes a risky decision.

Richard swaps pairings among the residents and attendings, baffling everyone. Meanwhile, Arizona makes a bold decision as she treats a woman who's carrying quadruplets; April faces a tough choice.

Jackson learns about April's pregnancy, while Alex and the team of doctors handles a long triple-organ transplant surgery. Meredith considers dating again, and Andrew insists on not receiving special treatment after he and Maggie go public.

Meredith takes a step forward with Will but quickly regrets it; Maggie senses a disconnection with Andrew; and Amelia reevaluates her relationship with Owen. Meanwhile, Catherine comes into town and really shakes things up with April and Jackson

April and Arizona find themselves arguing in switched positions. Richard tries to stop Catherine interfering in others' lives. Meanwhile residents are motivated to compete for a great research grant.

After a missing child forces the hospital into lockdown, Ben decides to operate on a pregnant mother without the proper surgical equipment. Miranda, as Chief, is faced with the repercussions of the event.

Miranda is faced with the repercussions of Ben's actions; Miranda forms an advisory committee

The doctors work frantically to save a young boy who was accidentally shot. Meanwhile, Arizona is upset when Callie tries to make an important decision about Sophia's future without consulting her.

Stephanie's relationship to Kyle becomes complicated. Meredith encourages Amelia and Owen to take a chance and choose to be a real couple. Arizona and Callie are at odds and put their friends in the middle of an uncomfortable situation.

Callie and Arizona are at odds over Sofia's future, and Stephanie questions the status of her relationship with Kyle. Meanwhile, Alex and April work on a pregnant teen that is readmitted to Grey Sloan Memorial.

Owen and Amelia take their relationship to the next level; Alex has a clearer view of his future with Jo; Callie and Arizona struggle with custody arrangements.

Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.

A crisis at the hospital cuts the wedding festivities short, Richard steps in with advice for Jo, and Meredith feels the burden of secrets.

Meredith thinks about her loyalties while Alex deals with the fallout of his actions; Amelia and Owen host a dinner party with surprising guests; Jackson makes a suggestion to help April through her recovery.

A family argues at the hospital following a car crash at a funeral; Arizona is caught between Alex and Andrew; Ben has a new parenting role; Amelia helps Meredith and Maggie work through a problem.

Alex realizes the clinic doesn't make him less of a doctor while Meredith struggles with professionalism with Riggs

Meredith and Bailey both have liver transplant patients; Owen needs to look after Harriet.

A familiar face returns to Grey Sloan throwing many of the doctors for a loop. With Catherine putting on the pressure, Bailey has to make a decision about Alex while a tough ER case makes Amelia's bad day even worse.

The arrival of a new consultant puts the doctors on edge; Amelia and Owen bring their personal problems into the hospital; April explores some unfamiliar territory.

A surgery brings back memories for Meredith, Richard, Owen and Stephanie.

Alex makes a decision about his future when it looks like he'll be going to jail. In the meantime, Richard wants to know why Eliza is at Seattle Grace as victims of a building collapse are brought in.

Bailey, Arizona and Jo treat a violent teenage girl and her unborn baby in a women's prison.

The attendings plot to make Eliza's first day at Grey Sloan difficult.

Maggie's mother unexpectedly visits; Bailey is forced to make a tough decision when an attending won't work with Eliza; Stephanie gets involved in Owen and Amelia's drama.

The residents get caught up in a conflict between attending physicians; April has a rough first day in her new role at the hospital.

Alex learns a lot has changed at the hospital since he left; Jo has to make a tough decision on a case; Arizona tries to keep her distance from Eliza.

Richard, Jackson, April and Catherine tackle a grueling trauma case intensified by hospital politics; Amelia finally faces her feelings about Owen; Meredith gets caught between Nathan and Alex over a patient.

Jackson and April go to Montana to perform a complicated surgery on a young patient.

Diane Pierce returns to Grey Sloan while Owen and Amelia collaborate on a trauma case.

When Maggie's mom's health deteriorates, the doctors are at odds over how to treat her. Meanwhile, Richard comes to grips with Bailey's betrayal over the Residency Program.

When Maggie takes on a big case, many of the doctors are worried she's not the right one for the job; Stephanie makes the mistake of treating one of Grey Sloan's own.

Meredith and Nathan must face their feelings when they end up next to each other on a plane.

Bailey and April work to fix things between Richard and Catherine; Eliza continues to pursue Arizona; one of Alex's previous patients returns to Grey-Sloan.

April and Andrew consult with a patient who has an inoperable heart tumor; Alex and Eliza disagree about the treatment of a young patient; Stephanie and Ben make major decisions.

The doctors of Grey Sloan encounter a difficult case involving a dangerous patient; Owen receives life-changing news that pushes Amelia to step up to support him; Alex attends a medical conference after making a shocking discovery.

A dangerous patient escapes the hospital room, putting the doctor's lives at risk; Alex faces a difficult decision in his relationship with Jo; Meredith has big news for Nathan.

Meredith and the team are focused on helping Owen's sister after her shocking return, and Amelia faces a conflict over a patient. Meanwhile, Bailey is forced to give Grey Sloan a facelift after the fire and the doctors are introduced to a few new faces that spice things up around the hospital.

Meredith struggles to come up with a new plan for Owen's sister. Jo makes a surprising choice regarding Alex, and Andrew's sister's controversial research leads to a shocking discovery.

Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith's past returns as a patient, and Amelia tries to manage a secret.

Amelia confronts a difficult situation; Meredith deals with the fallout from her conversation with Nathan; Maggie finds herself at an awkward family dinner; Jackson receives big news; Richard and Bailey search for the stars of tomorrow.

Hunt joins his sister for a drive, while memories from older times surface up.

Jackson invites the guys to relax with him on a day at sea; Arizona, April and Maggie treat a woman who is hiding a deadly secret.

After a roller coaster car falls off the track at the county fair, the doctors at Grey Sloan tend to patients who spark memories about ghosts from their past.

The doctors must get creative to treat patients after a hacker shuts down the hospital's computer system.

Jo finally faces her abusive husband, while Grey Sloan continues to work with the FBI after the hospital's computer system is compromised by a hacker.

A young boy's case has a profound impact on the doctors of Grey Sloan Memorial; April faces a surprising patient; Jo deals with her estranged husband.

The stress of managing the hospital and coming to terms with Ben's decision to become a Seattle firefighter pushes Bailey to her limits.

April is in charge of the new surgical innovation contest; the doctors are eager to start their projects; Catherine's old friend has a shocking idea for Catherine and Jackson; Meredith treats a returning patient who inspires her project.

Two boys injured in a house fire are brought to Grey Sloan and firefighter Andy Herrera's skills are put to the test when one of the boys is near death.

Maggie invites Clive over to meet Meredith and Amelia.

Relationships heat up at Grey Sloan-Memorial; Meredith tries to learn more about Marie Cerone.

Although he enjoys spending time with Maggie, Jackson must concentrate on the vaginoplasty surgery he scheduled with Catherine and Richard.

April treats a rabbi who challenges her crisis of faith and Meredith treats a transplant surgeon from another hospital.

Amelia and Koracick perform a risky procedure to remove a brain tumor from a young patient. Meredith and Jo re-work their project submission. Richard's AA sponsor is admitted with a DNR.

An agent from U.S. Immigration and Customs Enforcement searches the hospital for an employee; Alex's patient wants to leave the hospital to enjoy her final days, but Alex feels differently; Arizona treats Matthew Taylor's baby.

After a doctor accidentally brings in "weed" cookies, the hospital turns upside down

Crisis management is brought in to help Grey Sloan sort out allegations against Harper Avery; Alex and Jo are thrown for a loop when Nurse Olivia shows up with her son; Arizona spends more time with Sofia.

Alex and Jo go on a road trip to Iowa to find Alex's mom, whom he hasn't heard from in a very long time. Meanwhile, Meredith gives a presentation on her mini-livers project, which attracts a ton of attention, and Jackson works to rebuild the foundation after its reputation is threatened.

One of Grey Sloan Memorial's own is seriously injured, making the team reflect on what is truly important to them. Meanwhile, Nicole Herman pays a visit to GSM and talks to Arizona about an exciting opportunity.

It's the day of Jo and Alex's wedding, but things don't go as planned.

The doctors at Grey Sloan Memorial vie for a new position. Meredith is seemingly distracted and struggles to stay focused, and Maggie finds herself the keeper of a big secret while Amelia and Owen try to figure out their relationship. Meanwhile, Jo and Alex's honeymoon doesn't go exactly as planned.

New doctors continue to shake up the hospital in typical Grey Sloan manner. Meredith bonds with a patient while Jackson struggles with the meaning behind recent experiences; and after making a life-changing decision, Jo forms an unexpected alliance.

Meredith works on a patient who happens to specialize in matchmaking, and a seemingly drunk patient pushes Richard's buttons and gives him a medical mystery to solve. Meanwhile, Maggie tries to reach Teddy after bearing the burden of her secret becomes overwhelming as she struggles with issues in her own personal life.

Meredith turns heads when she shows up to work done up and ready for her blind date later that day, while Alex makes a questionable decision in order to save a patient. Meanwhile, the burden of knowing Teddy's secret keeps Maggie up at night, ultimately making her decide she has to tell someone.

Meredith turns to Teddy to help her during a difficult time; Owen and Amelia hide out close to Betty's school after she becomes a flight risk; Jo is ready to work on the fellowship, but Bailey's attention is in other places.

Meredith has a patient whose family is celebrating Day of the Dead, making the doctors remember loved ones they have lost. Richard shares unexpected news with Meredith about her father, Thatcher. Meanwhile, Teddy tries to tell Owen that she is pregnant but they get sidetracked, and Jo encourages Link to pursue one of the doctors.

Catherine is in Los Angeles getting the new foundation ready and summons Meredith and Koracick to visit for a confidential consult. Meanwhile, one of the nurses is 28 weeks pregnant and collapses at the hospital while talking to Richard.

Seattle is hit by a huge wind storm and Grey Sloan becomes inundated with patients. Alex and Jo are stuck at home and decide to make the best of it by having a second honeymoon, while Meredith confronts Richard about getting his life back on track.

When the power goes out at Grey Sloan, the doctors are left scrambling to save their patients' lives; Owen, Amelia and Teddy confront their complicated situation.

Meredith is troubled by Linc's nonchalant attitude. Once she has diagnosed Catherine, Maggie worried that Richard, Jackson and Catherine are not accepting the diagnosis. DeLuca get an advantage in the OR and Owen has some difficulties.