The Villanueva women have a tradition for Mother's Day and Jane (Gina Rodriguez) is excited to get to participate in her first one as a mom. However, their plans are thwarted when Petra (Yael Grobglas) invites everyone to a brunch instead. Jane's TA position is put into jeopardy when a mysterious ad appears in the college newspaper. Rogelio (Jaime Camil) is hurt when Dina (guest star Judy Reyes) doesn't invite him to her birthday party, so he asks Jane to help in an unusual way. Rafael (Justin Baldoni) finds himself in big trouble thanks to his half-brother. Meanwhile, Xo finds herself in a compromising position. Ivonne Coll and Brett Dier also star.

Jane and Michael's wedding plans go awry; Jane wants to change her graduate thesis but worries doing so will interfere with her big day; Rafael considers telling Jane about his feelings; Anezka has a health emergency; Xo gets unexpected news.

Jane goes on her book tour.