The West Wing staffers are introduced as each learns via phone or pager that the President was in a cycling accident. Josh faces the possible loss of his job after an on-air insult of a political opponent, which Toby tries to prevent by having Josh make a personal apology. Sam's fling the previous night with Laurie, who unbeknownst to Sam is a call girl, puts him in hot water, which he compounds when ineptly lecturing a class of 4th-graders about the White House and then asking their teacher which child is Leo's daughter. Leo must deal with the fallout from Josh's blunder, as well as 137 Cuban refugees who escaped on rafts and are seeking asylum. The president walks in during Josh's apology, recites the First Commandment, and lambastes three Christian pols for not denouncing a fringe group.

Josh trumps a potential Democratic challenger in a masterful political move and then hires the challenger's chief of staff and ex-girlfriend Mandy Hampton. Toby tries to warn Sam away from his friendship with the call girl, but to Toby's horror, Sam seems intent on reforming her. CJ tries to spin the latest clash between President Bartlet and Vice President Hoynes. After an American plane is shot down carrying Bartlet's physician, Bartlet's response leaves Leo worried about the President's response.

When India sends troops into Kashmir, President Bartlett calls for a British former ambassador to India to help out - over Leo's strong objections.

The President meets Zoey's new bodyguard on a 20-hour trip to California; Josh tries to keep a fund raiser from being canceled; Leo needs the VP to break a 50-50 tie in the Senate.

The staff waits for a poll to tell them if their new, activist policies are moving them in the right direction. C.J. feels like her opinions are being discounted.

With the midterm elections coming up, Toby looks for a way to stop hate groups; Charlie and Zoey decide whether to continue their relationship; President Bartlet discovers the egg cream and is concerned about an ultra-right-wing candidate running for school board in his old district in New Hampshire; and Sam is asked to put White House help behind an old friend running for Congress. This episode includes the President's confrontation with a right-wing radio talk show host using a famous list of modern applications of Biblical laws. Oh, yes, and psychics at Cal Tech and the Fermi National Accelerator Lab ...

Toby wants to use a bipartisan breakfast to discuss real issues instead of making it a staged event; Sam floats the idea of moving the press room across the street; Leo wants Josh to apologize to a columnist on his behalf; Leo and Toby realize they need to start thinking about reelection.

While a live TV show is broadcast from the West Wing following the State of the Union, the staff must covertly deal with a hostage situation in Colombia. CJ learns that a special guest at the state of the union has a black mark on his record that could taint the administration. Ainsley Hayes is afraid to meet the President in person.

Comments made by Surgeon General Dr. Millicent Griffith concerning the medical effects of marijuana appear to reverse the President's stance on legalizing the drug.

On this year's "Big Block of Cheese Day", a college friend of Donna's asks Sam to help her get her late grandfather, accused of being a Communist spy inside the U.S. government, a presidential pardon; dealing with the recent revelation that his father had been having an affair for the past 27 years, Sam faces off with an F.B.I. agent, and later with Nancy McNally, over the pardon. Elsewhere, a group of cartographers completely re-educates C.J. on her perception of the globe, and one-time protester Toby, with the help of a straight-talking female security guard, speaks for the w.h. at a rally to protest against U.S. participation in the WTO and various free trade agreements.

Josh finalizes a $6B health care plan that has strong support from both parties in both houses and appears to be a slam dunk for passage, but 78-year-old Senator Howard Stackhouse pulls a last-minute surprise--he wants money added for autism research or he'll filibuster. Thinking it's just a bluff, Josh blows off the senator, who then filibusters for more than eight hours while the WW staff waits desperately to begin their weekend with the episode unfolding as staffers write e-mails to their family members describing the evening's action. Elsewhere, Sam tries to eliminate various costly government documents, for which he's taken to task by a very young intern.

Following the Vice-President's remarks to him, Toby realizes the truth behind the President's illness: multiple sclerosis. Toby, Leo, and Bartlet discuss the possible political implications of this if it goes public including possible jail time for the 17 people who now know about the illness. Meanwhile Sam, Josh, Donna and the rest of the staff, unaware of the illness, struggle with a speech the President is to give at the White House Correspondents Dinner.

President Bartlett talks to the White House Counsel about the concealment of his MS. An enraged Toby has CJ grill the West Wing staff to find a leaker. Josh and Donna spar over a financial bailout of Mexico.

White House Counsel Oliver Babbish interviews CJ once she learns of the President's condition. The First Lady learns she may be legally vulnerable. Donna frets over news of a falling satellite.

As the Haitian army continues their seizure of the American embassy there, Bartlet and the staff prepare for the announcement that Bartlet has M.S. and the President must decide whether or he will seek re-election. As the funeral for Mrs. Landingham takes place and the announcement draws nearer, Bartlet thinks back to his past in search of the answer to the question everyone is asking: Will he seek re-election?

The staff is hunkered down in the Bartlets' hometown of Manchester, N.H., where they work with political consultants Bruno, Doug and Connie on the president's official announcement that he'll be seeking a second term; meanwhile, they all lament various W.H. events of the previous four weeks, including a huge strategic mistake by Josh, a pivotal FDA announcement scheduled for the same day as the president's speech, an ongoing battle between then president and first lady, and a major press room gaffe by C.J.

With the staff all bickering with one another in Manchester, especially adversarial speech writers Toby and Doug, who angrily disagree about whether Bartlet should make a public apology for lying about his MS, and with the president sniping at everyone, the second-term announcement speech is locked. Abby ultimately forgives the president for deciding to run again without discussing it with her, and he ultimately apologizes to the staff in private for keeping his condition from them, which they expect will soon lead to a whole slew of grand jury subpoenas.

While the W.H. is hosting a gala dinner for Nobel Prize winners, Leo and the president learn of a suicide bomb in an Israeli cafe that took the lives of two American students in Tel Aviv for a soccer match, and the staff attempts to manage the president's first veto, of a House bill eliminating the estate tax, and the threat of an override the same night. Sam and Toby first try to sway a contentious Dem. From Tennessee who wants a whole list of farming and ranching concessions in exchange for his vote and three proxies; after a pep talk from Leo, they devise a substitute plan that may prove even more effective, if it works. Josh takes the governor of Indiana into a private meeting to determine if the man plans to challenge Bartlet in Democratic primary. C.J. takes heat from a smarmy Dallas entertainment reporter who is in town for the Nobel dinner but winds up having to cover the veto and override vote, but after the reporter embarrasses her during a live stand-up, C.J. one ups the woman in front of the press corps. Later, Sam, Toby and Josh try to help the president decide what to say to the parents of the two murdered students.

CJ cannot control her outrage when the US agrees to an arms sale to Qumar, a country that brutally abuses women. Josh meets with Amy Gardner, a leading women's group lobbyist. The content of a Smithsonian exhibit draws protest from a veteran's group. Leo and the President discuss options when the possibility of a Mad Cow infection strikes the US beef industry.

In a private, late-night meeting, Cliff Calley informs Leo and Jordon he has negotiated a settlement in the Congressional witch hunt over Bartlet's MS: Bartlet can accept a joint congressional censure (House Concurrent Resolution 172, or H.Con. 172); Leo initially refuses to bring it to the president, insisting it will devastate the president and affect him for the rest of his life, but he does mull it over, and consults with Josh and repeatedly with Jordon about it; Josh begins his romantic pursuit of women's issues advocate Amy Gardner, but flubs it a couple of times while she continues dating other men.

On the night of the State of the Union, Sam has to explain the process of writing the speech and grading reaction to it to a magazine reporter (Traylor Howard) throughout the evening; C.J. arranged the coverage aware that the reporter, Lisa Sherbourn, is Sam's ex-fiancée; flashing back to the speechwriting process, we see the president dining with several of Abbey's medical colleagues, and they ponder the future of cancer research, motivating Bartlet to ask that a section be added to the SOTU in which he calls for U.S. scientists to find a cancer cure by 2012; the staff, convinced that the Congressional censure is weighing heavily on the president, tries to talk him out of this bold but risky proposal.

A small town in N.H. is the site of the first presidential primary vote, and the results from Hartsfield's Landing, announced at 12:07 a.m., will dominate the news all day until the final tally. Josh wants favorable press for the president, prompting him to ask Donna to persuade a local couple she knows to reconsider their vote. Elsewhere, Bartlet has just returned from India with a collection of antique chess sets he gives as gifts to the staff. He plays Toby while they discuss their recent blow-up, Bartlet's insomnia and Toby's fervent belief that the president's enormous intellectual gravitas is an asset, not a liability, to the campaign. He also plays Sam as they discuss a critical detente standoff between China and Taiwan. And Charlie and C.J. stand off in a series of pranks over a missing copy of the president's private schedule.

On a typical night in the west wing, Sam returns from a hockey game and Josh asks him to meet with V.P. Hoynes about saving an education bill. Back at the W.H., Josh, Toby, Leo, C.J., Larry and Ed all meet about the prospect of replacing Hoynes on the ticket in the next campaign. Bartlet helps Charlie do his federal taxes, and while both think Charlie should expect a refund, thanks to last year's so-called economic stimulus, he instead owes money to the IRS. A security emergency occurs when two trucks, one stolen and containing nuclear waste, crash in a tunnel in Idaho, threatening to explode and wipe out a nearby town. Donna asks Josh to ask the president for a special proclamation recognizing her favorite h.s. teacher. Bartlet can't oblige, but he comes up with a very uplifting consolation for Donna to let her teacher know how much she appreciated her. Episode title refers to James Bond's preference for "shaken, not stirred," which Bartlet insists results in a weak martini; this ties into Hoynes and Leo making the president aware that Hoynes is a recovering alcoholic, just as the w.w. staff is considering bumping him.

Bartlet and Leo debate on how to deal with the impending visit of the Qumari Defense Minister, whom U.S. intelligence officers have conclusively linked to terrorists. Sam dismisses an ingenious idea to trap Republican presidential opponent Robert Ritchie in an unsavory position over the Everglades, but comes around after talking to Toby. C.J. begins to develop a relationship with Secret Service agent assigned to her, Simon Donovan. Josh and Amy are locked into a battle over a welfare reform bill, which could end their relationship.

After Bartlet gives a campaign speech at an Indiana farm, Josh, Toby and Donna are left behind by the presidential motorcade and must work their way across the state with the help of the farmer's daughter and, later, a teenage campaign volunteer, enduring many setbacks along the way. Josh and Toby obsess and bicker over how best to play the president's intellectualism, viewed by many as snobbery, against Republican opponent Robert Ritchie's "regular guy" persona, while Donna must keep them on track and communicate with the real Americans they encounter along the way. Back at the W.H., the president deals with a terrorist attack at an Iowa college swim meet, meets with Leo, Nancy and Fitzwallace to discuss how to handle the prospect of the U.S. and/or Israel being accused of a conspiracy in the assassination of Qumari defense minister Abdul Shareef, and interviews secretarial candidates, including a second round with Debbie Fiderer; the wandering party finally arrive at a city with an airport (presumably South Bend) and stop briefly at a nearby hotel, where they learn about the Iowa attack and Donna chastises the two men for caring only about the campaign and not the people it affects; later in the hotel bar, Josh and Toby meet a man trying to figure out how to pay his daughter's tuition to Notre Dame, and he inspires them to initiate new tax policy.

Donna teaches Toby and Josh an important lesson as their trek homeward continues; Sam staffs the President in Josh's absence and welcomes an old friend home; Bartlet hires a secretary and C.J. finds a Big Brother for Anthony; the situation in Qumar continues to escalate; Bartlet gets spooked by a photo op as the Dow continues its dive; and a pipe bomb kills 44 students at a Midwest university swim meet.

Josh and Toby have a plan to make college cheaper. Leo starts talking to a lawyer about the Shareef assassination. A judicial ruling on third-party candidates has troubling implications for the campaign.

Sequestered in North Carolina to prepare for the one and only debate between Bartlet and opponent Robert Richie, the staff and several consultants (incl. Andrea Wyatt and Joey Lucas) flash back to the days just before and after the president's first inauguration, which were marked by an ill-advised choice for attorney general and ongoing concerns about fertility for then-married Toby and Andrea. In the present, Sam plays Richie in mock debates and raises Bartlet's ire, while Leo and the joint chiefs try to convince the president not to treat increasingly aggressive Qu'mar, whose defense minister Bartlet ordered assassinated (late last season), with kid gloves, and the staff keeps pestering Toby about his on-again, off-again relationship with Andrea, until he makes a startling revelation.

As results come in across the country, Sam is focused on a single congressional election that will determine his own future. After realizing she accidentally voted for the Republican nominee, Donna tries to find a Ritchie supporter who will "swap votes" with her. The President tries to hide a recurrence of his M.S.

Sam finds himself in a tricky position after the election in Orange County takes an unexpected turn. Toby and his ex-wife also find themselves in a delicate position, but decidedly one of their own making. And CJ tracks down the self aggrandizing source of some Process Stories.

A fight for Foreign Aid brings the staff together. Meanwhile Danny is uncovering evidence that is making certain members of the administration increasingly uncomfortable.

It is the day of Bartlet's second inauguration and yet the celebrations stutter as the staff are stunned by a betrayal in their midst.

Will struggles to find the words when the Inauguration speech seems to avoid current heart breaking issues.

The president, first lady and w.w. staff travel to Orange County, Calif., to campaign for Sam's bid to win the 47th District congressional seat -- the Nov. winner in the heavily Republican district was, amazingly, a liberal Democrat who, more amazingly, had died a few weeks prior. The president orders Toby to fire Sam's campaign manager, a staunch realist, and take over the campaign with a more idealistic approach. Some conservative voters approach Andrea Wyatt in a bar and give her grief about her out-of-wedlock pregnancy, and Toby and Charlie step in forcefully, landing them in jail. Donna talks, on behalf of Sam's campaign, with a state labor leader who turns out to be a Communist.

Military action in Africa has unforeseen repercussions. Sam and Toby work together on the Orange County Campaign. Will has to find his leadership skills quickly as he is left with no one but interns to prepare remarks on the dry subjects of Taxes.

The President, C.J. Cregg, Will Bailey, and others are returning from a long flight overseas. As Air Force One is about to land, the indicator light for the nose wheel fails to come on, prompting pilot Colonel Jessie Weiskopf to call off the landing, and notify the President of the possibility of terrorism. The White House Press Corps is on board, therefore CJ and Will must keep the story under wraps, due to it being a world market event. This becomes a challenge when a F-15 Eagle jet is sent to inspect the nose wheel on AFO. Meanwhile on the ground, Josh is working with Congressman Tom Landis (R-MD) on legislation to Clean-up Chesapeake Bay, which angers Congressional Democrats. Toby meets with Congressman Mark Richardson (D-NY) who has introduced legislation to reinstate the draft, furthermore Toby notifies the Congressman a soldier from his constituency was killed in action in Equatorial Kundu. Donna works with members of the 1st Airlift Squadron, 89th Airlift Wing to learn about "Angel Maintenance," in order to brief CJ, when she returns. Angel is the code word for the President's plane.

Trying to participate in a late-night staff poker game proves difficult as news arrives that an unmanned U.S. spy plane has crashed in a remote part of Russia, and Bartlet and Leo have to deal with an incensed Russian President Chagorin and convince him via phone to let the military go in and recover the plane; C.J. obsesses over the fact that on the exact moment of the spring equinox (today), you can stand an egg on end; Toby and Will have a card-flipping contest in the press room, during which someone from the street fires several bullets into the room; Debbie must "crash" the West Wing for the first time when the bullets fly; at the same time, Josh is interviewing associate counsel applicant Joe Quincy, and there's something about the well-qualified lawyer that bothers Josh, which he deduces during the lock down.

Seven hours have passed since Zoey's kidnapping and and the Republicans are in charge of the White House. Rifts are appearing in the leadership of both parties further complicated by the arrival of a ransom note demanding the release of terrorists.

A North Korean pianist announces his intention to defect in the Oval Office. While the staff passionately debate his request they also fight to get the President's choice of Vice President nominated by a new and hostile Speaker of the House.

Multiple members of the team start questioning the direction of the White House, including one member entertaining job offers. Those who aren't are starting to stumble, including Josh and Amy.

Leo is left manning the fort when the President goes AWOL whilst visiting tornado victims. Josh is not in the position to lend a hand as he deals with the fallout from a gross miscalculation and lack of judgment.

Press leaks lead to the revelation that former VP John Hoynes is about to release a tell-all book about the administration.

The president and staff are about to head for Brussels to sign an international free trade deal that Josh has just spent a lot of time and effort negotiating, to nearly everyone's satisfaction; at the 11th hour, the CEO of an IBM-like company tells Josh that the first effect of the new agreement, of which his company is a huge beneficiary, will be the immediate transfer of 17,000 programming jobs to India; the head of the communications workers' union, which is representing the affected programmers, brings one of the programmers to Josh's office, and they refuse to leave, leading Josh to question the underlying adverse effects of the trade deal. Throughout the episode, Ryan tries to make Josh care that he's completing his internship that day, while Donna pesters Josh to bring her on the Brussels trip in an effort to make her a more active player in west wing activities, eventually leading to a trade-off that will mean even bigger things for Donna in the long run.

Leo returns to the White House to help bolster the administration, which is suffering from the loss of Josh, Donna, Will, and the Vice President to the next election campaign. Leo's first day back follows President Bartlet's last State of the Union address, and unlike in previous years there appears to be little momentum on bold, large-scale initiatives. Amidst numerous distractions that dilute the focus of the staff (kidnappings in Colombia, the First Lady's appearance at a NASCAR race, and petulant Congressmen), he challenges the administration on their agenda for their remaining year in office.

CJ and Abbey go twelve rounds on how to handle President Bartlett and his disease. Lord Marbury makes his return to the White House after a British commercial plane gets shot down by Iran. Toby splits his time between helping write a Belarus constitution and the yearly meeting with Miss World

Toby's confession sends shock waves through the White House; Kate tracks developments following the assassination in Kazakhstan; the Santos campaign appears stalled.

Santos and his staff prepare for the inauguration as Bartlet and his team look back on their years in the White House.