Lucas wrestles with casting for his movie while Peyton tries to prepare for their future. Dan advises Jamie on a school crush. Brooke meets the actress who will play her while Nathan gets exciting news, and Haley has to make a tough decision at school.

Nathan and Haley are considering a better school for genius Jamie, but doubt that academic excellence outweighs posh elitism and absence of sports. Nathan is expected to step up as leader - by coaching his ingrate rival Nino. Peyton has a car accident, which wrecks Lucas' Comet on wheels. Sam's boyfriend has found cool foster parents, and must leave Victoria expects Brooke to help save the company she stole, if not out of family loyalty then for the employees.

Nathan is offered a two year pro contract, but in Europe. He agonizes whether he should take it, as Bobby suggests, or stick to his NBA dream, as Haley advices. Jamie not only does well at his first school dance, he is the one who counsels 'babsitter' Skills to date his teacher there. While Peyton grumbles bedridden, Lucas repairs the Comet as a surprise, while both reminisce. Chase must convince Mia his affair with Brooke was and could only happen before them. Haley enjoys working with Nick Lackey, who wants her to produce music.

Warned by manager Bobby there's an NBA scout, Nathan and his protégé Nino perform excellently, then wait for a call. Lucas opposes Peyton preparing a 'posthumous' time-capsule and ask for a rushed marriage on account of her pregnancy risk. Nathan makes him reconsider and drops off Jamie with 'his uncle Keith'. Brook, Sam and Victoria are too busy to concentrate on Peyton's baby-shower or business. They are preoccupied as to whether Sam should be encouraged to spend time with birth mother Rebecca.

Peyton and Lucas' wedding day has finally arrived and surprise guests attend. Haley plays an unexpected role in the ceremony while Nathan hopes to be called up to the NBA. Antwon keeps Jamie on a short leash, and Brooke does the same with Nick Lachey.

The tree hill gang must learn that to live an exceptional life doesn't end once you've achieved your goals. With Lucas and Peyton gone, Nathan's a year into his NBA career, Haley has taken over Red Bedroom Records, and has to deal with the return of her free-spirited 26 year-old sister, Quinn. Brooke is still happy with Julian.

Brooke looks for a model as the new face of Clothes Over Bros. Mia and Haley fall short of selling a million records. Dan finds a confidant in an unlikely person. Nathan deals with being distant from the ones he loves, while Clayton reminds him he's in the NBA. Tree Hill's former bad girl - Rachel Gatina returns.

After losing his place on the Charlotte Bobcats Nathan reaches breaking point with Clay and fires him but this ends up causing a rift between Haley and Quinn with Quinn moving out to a hotel. Dan takes it badly that Clay messed up and tries to teach him a lesson by nearly drowning him in the surf. Later Clay is fired by his boss for stuffing up Nathan's contract. Victoria arrives unannounced and takes a liking to new TRIC bar manager Grubbs. Meanwhile, Brooke tells Julian that it is doubtful that she will ever be able to get pregnant and he promises to get different opinions and they will work it out. Elsewhere, Millicent's increased drug taking alarms Mouth and her model like tendencies and demands disgust Brooke. It prompts Victoria to call the police when she sees Millicent driving drunk. Millicent calls Brooke from jail but Brooke tells her she cannot help her.

Victoria bails Millicent out of jail the morning after her arrest and tells her to get herself together before she shows herself again. But Victoria is doubtful that Millicent has learned her lesson and proceeds to keep an eye on her and she is proved correct when Millicent steals a dress from Brooke's new collection to give to her model friend Makenna is exchange for a packet of blow. Mouth is distraught at the change in Millicent and they break up. Clay tries in vain to hold onto his one client but it is not to be and so he packs up his apartment much to Quinn's dismay. Nathan is told by his agents that he won't play NBA this season and his only option is to play in Spain and be ready for the next season but this move coincides with Haley's planned record tour of the US. Skills records a video with the help of Jamie for a new job in L.A. Elsewhere, Julian mistakenly tells Alex that Brooke cannot have children which further deepens the rift between Brooke and Julian after Alex tries in her own way to help Brooke. Despondent after being told to stay away from Julian Alex slits her wrists in the bath and leaves Julian a voice-mail telling him she won't bother him anymore.

Clay gets his mojo back with some help from Quinn and which might mean that Nathan can stay in the US and play in the NBA with the his old team the Charlotte Bobcats instead of going to Spain. Skills gets offered and takes the job in Los Angeles and brings Mouth along for the ride. Dan goes against Rachel on his television show and tells his audience that this is his last show and also serves with divorce papers. Julian rescues Alex from her near suicide bid and tells her the film deal is back on. Brooke fires Millicent from her model contract and tells her to get immediate help for her drug problem but her stay in rehab is brief. Victoria hires a new designer, Alexander Coin, for the menswear collection without telling Brooke.

Nathan tries to calm Haley down after Taylor and David's shock announcement that they are a couple and then through the ensuing dinner that Taylor plans out until all three James sisters find themselves in the pool fighting it out. David and Quinn talk and he agrees with her that their marriage is at an end. Julian takes offense to the director hired for his new film and fires him after he punches him for insulting Alex. Finally after talking to Brooke rationally and asking her to be the movie's costume designer she makes him see that he should direct the movie himself which he brings up with his father who agrees. Mouth and Lauren fix up the disheveled apartment after Millicent's recent partying and then tells Millicent he is staying in Tree Hill. Millicent and Brooke agree to try and be friends again.

Haley and Quinn refuse to accept that their mom Lydia will not fight her pancreatic cancer and after some convincing manages to persuade her mother to get a second opinion with Nathan's doctor but the results don't bring any change. Because she told Jamie that she won't be alive for Christmas he organizes for her to have Christmas now with the family. Meanwhile, Brooke and Julian's relationship moves up a notch but comes crashing down spectacularly when Brooke finds Alex in his bed but is it what it seems? Elsewhere, Grubbs puts Miranda through hoops before he allows her to produce his album with her and Owen Morello comes back into Millie's life much to Mouth's displeasure.

In getting back at Julian for sleeping with Alex, Brooke messes with the costumes for the shoot and generally does her best to wound Julian but it takes comments from Alex to get her thrown off the set after she punches Alex in the face. Only later does she discover that it was Alexander that Alex slept with as she switched rooms with Julian. She tells Victoria who is furious and it later transpires that her mystery lover is Alexander. Meanwhile, Lydia takes ill from her cancer and is hospitalized and reaches out to the daughter Taylor but it is Quinn who manages to get her to come before she dies. Elsewhere, Clay tells Katie he won't be representing her but it doesn't put off Katie and she finds out that he was married to Sara so she transforms herself to look like her. Lauren and Mouth nearly get it together only for Skills to come back to Tree Hill.

Quinn's gallery opens with Clay very supportive unaware that he is being stalked by Sara lookalike Katie until she makes her presence known and Clay shows Quinn how alike Katie is to Sara. Josh's sex tape with Alex is emailed to Julian's father with a demand for $1,000,000 putting the film in jeopardy. Miranda finds out she is being deported thus putting a spanner in the works with Grubbs's recording but Grubbs finds a way around it by proposing to her. Lauren tells Skills that she has fallen for someone else but he is unaware it is his best friend Mouth until he sees a photo of them at the gallery where he promptly punches Mouth. Meanwhile, Victoria's affair with Alexander is exposed in more than one way. Elsewhere, Nathan and Jamie spend a guys evening together & later he asks Haley if she'd be ready to try for another baby. She tells him she took a pregnancy test and it was negative but is she telling him the whole story?

Nathan and Haley struggle with the aftermath of her mother's death, while Brooke deals with the fallout of Alexander's tryst with Victoria. Alex discovers a secret about her leading man, Josh, that could derail Julian's film, and Quinn is confronted by an unhinged Katie.

A storm strikes Tree Hill, putting everyone's life in danger.

As the girls plan a surprise baby shower for Haley, the guys participate in try-outs for Jamie's baseball team. Meanwhile, Brooke and Julian pursue adoption, while Mouth gets Millicent ready for her first day at work.

Nathan, Jamie, Clay, Julian, Chase and Chuck have a camp-out on the Rivercourt. Meanwhile, Brooke, Quinn, Alex and Lauren take a trip to Puerto Rico.

Chase is heartbroken after Alex's desertion to take the tour Chris Keller advised, yet overcomes his bitterness toward Keller, who pleads her artist temperament was a lost case from the start. Julian is near despair about the unused studio until a TV series project comes within reach. Alas coaxing the studio proves tragically incompatible with paternal duties, while Brooke charms investors for her boys fashion project with her father. Clayton's problem is worse then thought, as Quinn discovers spying on him. Haley now runs Karen's café, but her cook is sick, so Dan steps in but that costs some bigot customers, and a mystery competitor opens across the street.

Haley receives news of a possible tragedy. Dan's search for Nathan leads him back to his dark past. Clay has a breakthrough in his treatment. Brooke and Julian deal with Xavier. Chase's concern for Chuck pushes him to his limits.

Nathan, Jamie, Clay, Julian, Chase and Chuck have a camp-out on the Rivercourt. Meanwhile, Brooke, Quinn, Alex and Lauren take a trip to Puerto Rico.

Haley and Quinn refuse to accept that their mom Lydia will not fight her pancreatic cancer and after some convincing manages to persuade her mother to get a second opinion with Nathan's doctor but the results don't bring any change. Because she told Jamie that she won't be alive for Christmas he organizes for her to have Christmas now with the family. Meanwhile, Brooke and Julian's relationship moves up a notch but comes crashing down spectacularly when Brooke finds Alex in his bed but is it what it seems? Elsewhere, Grubbs puts Miranda through hoops before he allows her to produce his album with her and Owen Morello comes back into Millie's life much to Mouth's displeasure.

In getting back at Julian for sleeping with Alex, Brooke messes with the costumes for the shoot and generally does her best to wound Julian but it takes comments from Alex to get her thrown off the set after she punches Alex in the face. Only later does she discover that it was Alexander that Alex slept with as she switched rooms with Julian. She tells Victoria who is furious and it later transpires that her mystery lover is Alexander. Meanwhile, Lydia takes ill from her cancer and is hospitalized and reaches out to the daughter Taylor but it is Quinn who manages to get her to come before she dies. Elsewhere, Clay tells Katie he won't be representing her but it doesn't put off Katie and she finds out that he was married to Sara so she transforms herself to look like her. Lauren and Mouth nearly get it together only for Skills to come back to Tree Hill.