The firm worries about its reputation when Kittredge takes a high-profile criminal case of defending a mobster leader for allegedly murdering a rival mob leader and the new D.A., Ruby Thomas, becomes determined to see the case won at any cost. Meanwhile, Markowitz takes a rare court deposition in representing two women basketball players suing the Hollywood Hoopsters for wrongful termination.

Mullaney and Zoey are on opposite sides in the prosecution of John Harvey, an accused, Ted Bundy-type serial killer, who manipulates the jury and both of them. Meanwhile, Brackman, Kelsey and Marktowitz deal with Giles Keenan, an eccentric businessman who comes to the firm for representation in landing a multi-million dollar movie deal. But Keenan's true sanity becomes an issue when Kelsey eventually voices her concern about it. Also, Bloom heats up her personal war with McKenzie when she videotapes him and Grace in a compromising position.

Mullaney aids fellow lawyer, Alex DePalma, in a class action suit by Honduran banana farmers suing an American chemical company who claim that a company-designed pesticide made them sterile. Meanwhile, Margaret Flanagan (The district attorney who unsuccessfully prosecuted Earl Williams for the murder of Nina Corry in Season 4) confides in Zoey about her troubled past as she begins to confront long-repressed memories of child abuse. Kelsey goes out on a dinner date with Matthew's nanny, Ned, while Markowitz meets a regal actress he admired as a child.

Grace receives a lot of hostility from her female colleagues when she defends a college baseball player accused of date rape. Meanwhile, Alex DePalma becomes embroiled in a complex courtroom sting operation headed by Ruby Thomas to nail a corrupt judge. Roxanne and Becker's tentative relationship is nearly capsized by Julie's revelations to her. Also, Markowitz gets Sarah a job at the firm with Kelsey's tentative approval.

Becker tries to win back Roxanne after his psychologist suddenly dies during a session. Meanwhile, Brackman and his ex-wife, Sheila, clash again when their youngest son, Alexander, gets in trouble with the law. Susan Bloom shocks the office with invitations to her unexpected wedding to Mikhail, a Russian movie actor. The Markowitzes' nanny, Ned Barron, went too far when he comes on to Ann Kelsey again and he is fired. DePalma asks McKenzie for help when his participation in the judicial sting operation impairs his ability to function in court when faces the wrath of other judges in his quest to find one for his latest case involving defending an alleged embezzler. Ann Kelsey was arrested for obstruction of justice and suspicion of illegal aliens by INS Agents when she bought a new nanny and having her son Matthew returned home. Also, Gwen and Kittredge's romantic fling quickly turns into a torrid affair.

Zoey is prosecuting a corrupt multimillionaire who tries to buy his way out of a murder charge after a hit-and-run that killed a homeless man. Meanwhile, the Brackmans and Benny must face each other in juvenile court after Sam and Alexander get into trouble together. The Markowitzes ask a reluctant Sarah to be Matthew's new nanny. Also, Bloom and Mikhail face their first INS interview while Mikhail makes a play for C.J.

Zoey helps a jail house lawyer with his case in defending another inmate for murder. Meanwhile, Sarah gives her mother and the Markowitz a cause for worry when she starts behaving rebellious over her mother's disapproval of a new boyfriend. C.J. faces off against David McCoy, a crafty blind lawyer, while she is defending a Hollywood studio chief being sued by a aspiring actress who places the blame for her faulty breast-implant surgery. Bloom experiences very mixed emotions when Mikhail and a starlet actress steam up the camera lens during a movie shoot. Also, Becker seeks a way to get back at Kittredge for destroying his case.

Becker meets with an AIDS-stricken ex-lover, Paige Dietrich, who needs a will drawn before she dies, and Roxanne gets a blood test when she learns of Becker's past connection with Dietrich. Meanwhile, Victor Sifuentes visits Grace with a marriage proposal. DePalma is representing a ex-convict, also dying from AIDS, who is suing the medical board to keep him covered on their insurance. Brackman and Sheila get more intimate and decide to remarry.

October 29, 1992. Six months after the trauma of the L.A. riots, McKenzie finds himself haunted by a murder case he prosecuted in 1959 of Frank Osgood, and that Morales has reopened the case after another man has confessed to the crime. Meanwhile, Markowitz returns home from the hospital shaky and frightened after his head injuries. Brackman find himself in legal trouble as he tries to fight the new fledgling D.A., the self-assured Dana Romney who's prosecuting him for resisting arrest. An all-new Becker returns from a six-month trip around the globe. Mullaney interviews with the D.A.'s office for a job to relish his renewed relationship with Zoey. Also, Rollins contemplates an caressive new campaign strategy after losing a key endorsement, but may regret it.

Due to the stress of her return to work, Zoey opts to be out of the D.A.'s office and decides to leave L.A., and Mullaney. Meanwhile, Rollins' campaign sinks lower and lower as the election draws near. Becker looks inward to his future, but Roxanne sees just the same old Becker. In jail, Brackman learns about his new life from behind the bars. Markowitz is slow to heal and frustrations set in for him and Kelsey. Mullaney becomes aroused in his first case for the D.A.'s office in prosecuting a man in a child-abuse case, who is being defended by a nun lawyer.