Carol Hathaway returns to work after her suicide attempt. Doug Ross still feels guilty about what happened. An ER patient found walking the streets takes to singing, constantly. Susan Lewis has a run-in with the cardiologist on duty, Dr. Kayson, when he disagrees with her treatment of a heart attack victim. At a case review session, she gets very little support from her colleagues. She also treats a woman who is dying of leukemia and who has good advice for Hathaway. Greene treats a woman who has obviously been beaten by her husband but can't get to agree to get help.

Drs. Benton and Langworthy are unsuccessful in reviving a teen-aged boy involved in a traffic accident and it's left to Carter to determine the boy's identity and notify the parents. Unfortunately, he tells the wrong parents that their son is dead. Doug Ross tells a young patient that he will not be separated from his schizophrenic mother knowing that she will likely be hospitalized for a long time. Susan Lewis tells Mark that she is dating the psychiatric attending physician Div Cvetic. She also treats a salesman whose cell phone is having an odd effect on hospital equipment. Benton forgets that he was supposed to sit with his mother while his sister and brother-in-law were to go out for their tenth anniversary dinner.

Carol Hathaway faces an ethical dilemma when a patient admits that he, and not his friend, was driving the car that ran a red light and killed a pedestrian. She decides to tell Tag about kissing Doug Ross. It's Thanksgiving and the doctors treat an animal rights activist who was attacked by the turkey he was trying to save. Doug Ross is going to the Bahamas with Linda Farrell and he is very much feeling like a kept man. Carter has to treat a transgender woman who has now reached an age where she can no longer pass as a woman. Carter's indifference is the final straw. Susan Lewis continues to worry about Div Cvetic, whose condition seems to be worsening.

While victims of a gang shootout are being brought in, Carter is late and a new group of third year medical students arrives.

It's Weaver's first day and she doesn't exactly make a lot of friends. Carol rides along with the paramedics.

The feud between Susan and Weaver gets to the point where Mark has to step in.

Doug and Harper had sex. Mark finds out about this. So does Carter.

Doug gets the opportunity to stay at the ER thanks to the publicity surrounding his rescue of a drowning boy the week before.

Rumour has it there's something going on between Mark and Susan while Benton questions Vucelich's study and confronts him.

Carter is very nervous because he's about to get his residency match. Mark changes his look.

Benton dismisses a patient he hasn't seen who should have been admitted. Carter competes with Dale, a new surgical resident-in-training who once slept with Harper.