Dr. Corday suggests a quick surgical procedure for a patient with back pain before taking off on a romantic weekend with Dr. Greene. Abby's mother, Maggie, unexpectedly visits the hospital and wreaks havoc on Abby's life. Dr. Chen needs the father of her baby to sign paperwork to go through with the adoption.

Abby's mother decides to stay in town; Carter attempts to find a drug addict who left the hospital: Greene discovers his health is failing.

Maggie's emotional instability worsens. She refuses her medication, becomes combative and flees the hospital. Abby finds solace with Kovac. The gang member girlfriend of Benton's deceased nephew knows who killed the dead boy who was hated for his antigang stance.

Abby and Carter travel to Oklahoma to rescue Abby's mentally ill mother and bring her back to Chicago. In Chicago, Maggie suffers from a sleeping pills overdose. At County General, Kovac frantically revives her. Benton treats a college student injured in a fraternity prank.

Maggie contests Abby's attempt to institutionalize her. Weaver treats a few bizarre patients. When Legaspi returns to work after being exonerated of sexual harassment, Weaver tries to reconcile with her. Benton injures his hand while transporting his former teacher to the hospital and must contend with the teacher's wisecracking elderly buddies (TOM BOSLEY and TOM POSTON).

Cleo and Carla clash after Reese gets hurt while in Cleo's care. Weaver and Kovac cannot save the life of a developmentally challenged woman's only caregiver. Abby goes to a therapy session with Maggie. Later, Abby confesses to Maggie that she is afraid to bear children because they might be bipolar like her mother.

Abby helps a distraught boy whose mother died of a stroke; a man with schizophrenia, who once stabbed Carter and killed a doctor, is brought into the ER.

Abby's family nightmare continues as she searches for her missing brother Eric, who she suspects is suffering from serious mental problems. Gallant accompanies her to his military base where they find Maggie, whom Eric turned to for help. When he's transferred, Abby and Maggie go to a Midwestern air force base, hoping to prevent Eric from being court-martialed for being absent without leave. Carter struggles to get out of Chicago to join Abby. Meanwhile, Corday treats a family of patients who, while building a snowman, were severely injured after being struck by a truck driver. She must help the father, Stuart, make a life-or-death decision. Corday also sympathizes with troubled surgical resident Paul Nathan as he struggles with the increasing symptoms of his physical handicap.

Harkins faces a tough call while treating a troubled teen involved in a car crash with her dad; Abby races to stop Maggie from taking manic-depressive Eric out of treatment; and Kovac hits a new low when an elderly woman tips him for his medical services. Meanwhile, an abandoned baby dredges up painful memories for Chen; and Pratt goes to bat for Leon after he's fired from his job for stealing.

Abby comes close to breaking down trying to deal with her mother. Dr. Pratt goes for his required paramedic ride-along. Dr. Weaver confronts the man who stole her purse. Dr. Lewis has a teen admirer.

The police question Drs. Pratt and Gallant about a rampage at the diner across from the ER. Dr. Lewis befriends her teen admirer, a cancer patient.

As Abby and Luka cope with their newborn's life and death struggle, the couple is shocked to receive a surprise visitor: Abby's mother Maggie. Meanwhile, Sam fears the prospect of criminal charges; Neela discovers that Tony Gates will be joining the ER team as an intern and Morris gets his job back while Weaver gets demoted.