Can Sylar be stopped? Will Linderman's vision live on with Nathan? What will it take for Peter to save the world, what sacrifices will be made? With all the horrible predictions unfolding before them the heroes face moments of pain and peril in Kirby Plaza.

Four months after the events of Peter's explosion, we find the heroes at different places in their lives. Claire, HRG and family try to stay below the radar in their new town, but a classmate of Claire's with some powers of his own knows there's something different about her. Matt Parkman and Mohinder Suresh are now guardians of Molly Parker, who has been suffering from horrible nightmares about the man who is more evil than Sylar. Mohinder and HRG are still trying to take the company down. Kaito Nakamura and Angela Petrelli receive ominous notices of their impending deaths, clearly sent by one of "the elders". Nathan has pushed his family away and is in a very dark place, feeling that Peter has survived and is alive somewhere. In Ireland, we find Peter Petrelli is alive, but doesn't remember who he is. Maya and Alejandro, two new characters, are wanted for murder due to her accidentally killing multiple people because of her ability to host a plague.

Having lied to her father about joining the cheerleaders, Claire decides the time has come to teach the team captain a lesson when she is told that she didn't make the squad. Having convinced Monica to come to New York, Dr. Suresh isn't at all comfortable when the Company asks him use her as a guinea pig for a variant of the vaccine. The Company backs down but he learns that Niki Sanders has been assigned to work with him. Alejandro and Maya make it to the US border only to be stopped by a citizens border patrol unit. Having painted a Menendez-like painting, Peter Petrelli heads for Montreal to see if they can get some clues as to who Peter really is. Hiro may ruin the time-line when he gives in to temptation and kisses Yaeko only to learn that Takezo Kensei was watching them. HRG man and the Haitian visit an old colleague from the Company in an attempt to locate Isaac Mendez's last paintings. They show that they are more than ready to use violence to get what they want.