While working in the night shift at the Daily Planet, Chloe receives a distressed phone call from a woman claiming that she is in danger. Chloe and Lois schedule a meeting with the woman, but a car runs over her and the cousins witness the murder. Meanwhile, the close friend of Jonathan, Senator Jack Jennings, visits the farm to rest from his campaign for the senate against Lex Luthor. Jonathan is surprised by the visit of Detective Maggie Sawyer, who is investigating the death of the nineteen-year-old stripper that Chloe and Lois witnessed last night. She found a picture of Senator Jennings with the girl and is following the lead. Clark believes Lex is involved with the crime, but Lex helps him in the investigation. Lois decides to go undercover by working at the nightclub as a stripper to investigate the murder. When Lois meets the criminal, she is abducted and her life is in danger.

Clark and Chloe discover that Titan, another alien escapee from the Phantom Zone, is the hulking star of a secret fight club whose bloody, bare-knuckle battles to the death are broadcast on the Internet. Lois smells a story and investigates on her own but is captured by fight manager-presenter Maddox, the Belle Reve administrator, and forced to become wrestler Athena's first opponent. To save Lois, Clark reveals his ability to catch bullets to Maddox so he can fight Titan, but is stunned to face Lois in the ring instead... Lana returns from her honeymoon with Lex, whose men are looking for Titan, but she's more uncertain about living the life of wealthy and power and has trouble with her pregnancy.

Kara desperately wants to make friends and fit in on Earth, but Clark tells her to keep a low profile until she can get her powers under control. Despite his warnings, when Smallville's annual "Miss Sweet Corn" beauty pageant comes around, Kara signs up and meets the competition; Tyler, Carly, and Tempest, three meteor-infected vixens who plan to use their powers to steal a treasure map to the hidden Smallville time capsule. Meanwhile, Lana returns to Smallville and wants to re-start whatever romance she had with Clark. In Metropolis, Agent Carter interrogates Lex in his further search for Kara's missing spaceship, while Chloe and Jimmy clash with the vain and egotistical Grant over the developing story in Smallville.

Tess acquires a Kryptonian box that once belonged to Lionel Luthor. When Clark accidentally activates the box, he's transported to a parallel universe where Lionel found Clark in the cornfields instead of the Kents. In this universe, Clark Luthor is a murderer and Lois is engaged to Oliver and both of them hate Clark. Clark must be careful not to tip off Lionel that he's not his son while trying to figure out how to get back to Earth where the monster Clark Luthor was transported in his place.