Chloe visits a former friend of her father in Luthor Corp. to know if he is blacklisted, since all his applications are not accepted and he is not able to find a job. She steals his security card and breaks in the Luthor Corp. laboratory trying to find evidence. But she gets accidentally exposed to a meteor-rock gas which gives her the ability to makes people tell the truth whenever she gets in close contact with them, thus exposing their innermost secrets. Chloe uses her new ability to explore her curiosity of journalist, hurting people, including her history teacher, Martha, Lana, and Pete, thus showing the dangerousness of the absolute truth when she attempts to question Lionel about his criminal past, and she gets more suspicious about Clark when she learns that he is the only one immune to her 'truth' powers. But when Chloe falls ill from the side affects, Clark risks his secret becoming known by trying to save her by trying to find the scientist responsible for the kryptonite gas concoction. Meanwhile, Lex continues to uncover evidence against his father to find the grounds for the FBI to arrest him on.

Simone, a gorgeous blonde, comes to Smallville hypnotizing Clark with a blue pendant ruining his relationship with Lana, as well as hypnotizing Martha and Lex.