The rangers help a Mexican security team protect a political candidate from an assassin.

An agricultural company produces cattle feed that contains a virus. Instead of recalling the feed, they let the virus spread for research and a way to make it better. The virus affects almost everyone in town.

Sam Coyote, Walker's friend, the Sheriff at the Cherokee reservation has been seeing Nora Shannon, an archaeologist who's been working on the reservation. When he proposes and she refuses things between them go bad. At the same time an oil magnate who knows that there's oil under Shannon's site plans to get it. And part of his plans is to kill Nora and frame Coyote. While Walker has no doubt that Coyote's innocent; the Feds don't think so. So in order to keep them from taking Coyote off the reservation and buy some time to prove his innocence, Walker has Coyote's deputy arrest him and with help from the Tribal Judge to stall the Feds.

CD gets a job as acting Chief of Security at a Resort. When he asks his assistant, Grady what happened to his predecessor, Grady tells him that he had a drinking problem and disappeared. And it's only half right, he disappeared cause he caught Grady doing something without his permission so Grady killed him. Walker is told by the Commissioner that several of the wealthiest men in the country will be going to the resort that CD works at so he wants Walker to go there and covertly keep an eye on things. So he goes there and Alex goes with him posing as his wife and Trivette goes there posing as a venture capitalist.

Loretta Lynn's daughters play themselves as a country singing group. The Lynn Sisters are kidnapped and forced to record their music for a bootleg music mongrel.