Annie continues to suffer through her mother's recent diagnosis. Annie then decides to go to Arizona to visit her parents and see what is going on with them. Meanwhile, Eric volunteers for a charity work, but he's unable to do it at the last minute. Matt then volunteers to do it, but his dating habits get him into trouble with the organization he is doing charity for. Also, Mary decides to call it a quits with Jeff while Lucy has her first real date with her classmate Jimmy Moon. Lastly, when Annie returns home with her parents, they decide to stay with her and the rest of the family so that they could spend some more time with them--which unfortunately will be the last for Annie's mom, Jenny.

Matt gets bad news from his girlfriend, and goes to Philadelphia; Mary calls it quits with Wilson; Ruthie learns a lesson about kissing at school.