Dr. Preston Burke is a fictional character portrayed by Isaiah Washington in the TV series Grey's Anatomy.
In the first episode they appeared in, titled A Hard Day's Night (season 1), they were 41 years old.
They appear in 63 episodes out of a total of 430 aired so far and have accumulated 20961 positive votes.
The character of Dr. Preston Burke is mainly associated with Dr. Alex Karev and Dr. Izzie Stevens.
Episodes63
A Hard Day's Night
episode S1.E1 march 2005The first shift for new surgical interns Meredith, Cristina, Izzie, George, and Alex proves eventful and backbreaking.
The First Cut Is the Deepest
episode S1.E2 april 2005A rape victim is admitted, who managed to hold onto part of her attacker; Izzie has difficulty with a patient who cannot speak English; Meredith becomes concerned about a sick baby.
Winning a Battle, Losing the War
episode S1.E3 april 2005Izzie and Cristina are assigned a close-to-brain-dead John Doe who may be a viable candidate for organ donation, and helpful to George's patient, who needs a new liver. Meanwhile, Meredith and Alex butt heads over a patient of their own.
No Man's Land
episode S1.E4 april 2005Alex uses Izzie's modeling against her, and her last ad causes a patient to reject her care. Meredith finds parallels between a patient and her mother, and Christina must deal with a hospital-savvy patient.
Shake Your Groove Thing
episode S1.E5 april 2005Meredith worries she did something wrong during a heart bypass, an error in a past procedure is discovered, putting a staff member's conduct under scrutiny, while a party thrown by Izzie to introduce her boyfriend becomes a fiasco.
If Tomorrow Never Comes
episode S1.E6 may 2005A woman with a massive tumor is admitted, with all the surgeons required to scrub in. In their absence, Meredith is assigned a patient with Parkinson's and, because Alex's pager is not working, Izzie is left in charge of the floor herself.
The Self-Destruct Button
episode S1.E7 may 2005Izzie and George find out about Meredith and Derek, while Cristina makes a discovery of her own. George thinks an anesthesiologist is drinking on the job, and Meredith deals with a young girl who has had illegal surgery.
Save Me
episode S1.E8 may 2005Meredith wants to learn more about Derek, but he remains cagey. Meanwhile, a supposedly psychic patient proves bothersome, Alex must convince a young girl to agree to a life saving operation, and Cristina is conflicted about her pregnancy.
Who's Zoomin' Who?
episode S1.E9 may 2005George finally gets laid but gets syphilis. It's rampant among staff. Surgeon Webber is losing his sight. He wants Shepherd to operate secretly. A male patient has an ovary. A lifesaving autopsy's performed without consent.
Raindrops Keep Falling on My Head
episode S2.E1 september 2005Meredith, shattered by revelations, is forced to work with Addison, Joe collapses at the bar, Cristina has some pretty shattering news of her own, and Alex starts working on Izzie.
Enough Is Enough
episode S2.E2 october 2005A family is admitted after being involved in a car crash, but there is more to them than meets the eye. Meanwhile, Bailey and her team deal with a strange case, and relationship woes plague Meredith, Cristina and George.
Make Me Lose Control
episode S2.E3 october 2005Meredith is horrified when her mother is admitted, and everyone is concerned when Cristina collapses in the operating room. Meanwhile, Addison is determined to save a very sick baby.
Deny, Deny, Deny
episode S2.E4 october 2005Cristina is determined to get back to work, and despite not being fully recovered, she manages to crack an odd case. Meanwhile, Addison offers to help Bailey with a complicated surgery, and Alex receives important news.
Bring the Pain
episode S2.E5 october 2005A storm rages, causing power outages and jamming the elevator, trapping George and Alex inside with a vulnerable patient. Meanwhile, Meredith and Derek arrange a religious ritual for a young woman, and Cristina deals with an unusual case.
Into You Like a Train
episode S2.E6 october 2005A train wreck brings in multiple casualties, leaving Meredith hanging for her answer. Meanwhile, Alex finds working without his mojo a disheartening experience, and Cristina searches high and low for a missing appendage.
Something to Talk About
episode S2.E7 november 2005Derek reluctantly attends marriage counseling with Addison, while Meredith, Izzie and Cristina steal a patient with an unusual problem. Alex helps a young patient gain her independence, and Cristina thinks Bailey knows about her and Burke.
Let It Be
episode S2.E8 november 2005Friends of Derek and Addison come from New York for a preventative surgery that causes discord among both couples. Meanwhile, George helps a man who has fallen from a roof, and Bailey delivers news to the Chief.
Thanks for the Memories
episode S2.E9 november 2005Thanksgiving sends the occupants of Meredith's house in different directions: Meredith escapes to the hospital, George goes hunting with his family, and Izzie throws a dinner to which it appears no one is coming.
Much Too Much
episode S2.E10 november 2005Meredith's one night stand causes complications when he shows up at the hospital with an embarrassing problem. Meanwhile, Burke tries to push Cristina toward the next step, and Alex's problems affect his performance.
Owner of a Lonely Heart
episode S2.E11 december 2005The mother of the quints blames herself. Meanwhile, Izzy becomes attached to her patient, Karev must face the consequences of his actions, and Cristina takes care of an inmate desperate to stay at the hospital.
Grandma Got Run Over by a Reindeer
episode S2.E12 december 2005Christmas hits Seattle, with Izzie caring for a man who fell from his roof while hanging decorations. Meanwhile, Cristina helps perform a heart transplant on a depressed boy, and George has to contend with the family from Hell.
Begin the Begin
episode S2.E13 january 2006Izzie becomes attracted to a male patient with a heart condition, and George treats Bex, an intersex patient. Meanwhile, Meredith's mother receives a visitor, and Derek and Addison's relationship is still rocky.
Tell Me Sweet Little Lies
episode S2.E14 january 2006Meredith must choose between her dog and her roommates. Meanwhile, George deals with an elderly patient who has outstayed her welcome, Bailey's pregnancy has complications, Alex gets his exam results, and Richard has a strike on his hands.
Break on Through
episode S2.E15 january 2006The nurses are striking, and George refuses to cross the picket line. The interns are surprised by Bailey's seemingly immature replacement, Izzie connects with a pregnant girl, and an elderly woman's plight pushes Meredith to the limit.
It's the End of the World
episode S2.E16 february 2006The lives of everyone in the OR are threatened when a patient enters with a bomb inside him, and a young paramedic with her arm inside the cavity is the only thing keeping it from going off.
As We Know It
episode S2.E17 february 2006While the man with the bomb lodged in his chest remains in Burke's OR with Meredith's hand in the cavity, Bailey's injured husband remains in Derek's. Meanwhile, Bailey's distress puts her unborn baby at risk.
Yesterday
episode S2.E18 february 2006Derek and Addison are shaken by the arrival of a figure from their past. Meanwhile, Burke learns Cristina's secret, Izzie deals with a very unusual case, Meredith delves into her family's dirty laundry, and George pours his heart out.
What Have I Done to Deserve This?
episode S2.E19 february 2006Meredith and George face the consequences of their actions, Izzie gets closer to Denny, who has been readmitted, and Addison asks for Bailey's help with an embarrassing ailment.
Band-Aid Covers the Bullet Hole
episode S2.E20 march 2006Cristina babysits for Bailey and does not take to it well at all. Meanwhile, Addison and Derek come to terms with their relationship, George connects with Callie, and Denny continues to come between Alex and Izzie.
Superstition
episode S2.E21 march 2006Superstition strikes, with the interns convinced a series of deaths will occur. A complication from the LVAD surgery puts Denny in the OR, Cristina plans to make George move out, and Richard's old AA sponsor is admitted for treatment.
The Name of the Game
episode S2.E22 april 2006Cristina is desperate for George to move out of the apartment, while Izzie is jealous of Callie's relationship with him. Meanwhile, Cristina and Richard are rivals in a surgery seminar, and Meredith discovers a secret about her father.
Blues for Sister Someone
episode S2.E23 april 2006Meredith considers going on a date with Finn, and Izzie tries to find out more about George and Callie. Meanwhile, Alex clashes with Addison over a sensitive case, and Burke is nervous about operating on a patient who is one of his heroes.
Damage Case
episode S2.E24 may 2006The victims of a serious car accident are admitted, with every surgeon required to help. Meanwhile, Callie's forwardness grates on Izzie, Addison makes Alex suffer, and Derek takes his frustration out on Meredith.
17 Seconds
episode S2.E25 may 2006The victims of a workplace shooting are admitted. Izzie puts her job on the line to ensure Denny gets a new heart, Callie makes an effort with Meredith, and Addison is suspicious of Derek.
Deterioration of the Fight or Flight Response
episode S2.E26 may 2006Burke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.
Losing My Religion
episode S2.E27 may 2006Richard is determined to discover the guilty party, and punishes the interns by making them arrange a prom for his niece. Meanwhile, Callie presses George about his feelings, and Derek and Meredith have to make a decision about Doc.
Time Has Come Today
episode S3.E1 september 2006Everyone reminisces about the past. Meanwhile, Izzie is emotionally devastated, with the others trying to help her, Adele gives Richard an ultimatum, and George and Derek are put in quarantine when an outbreak of the plague is suspected.
I Am a Tree
episode S3.E2 september 2006Izzie copes with her grief by baking furiously, and George has to deal with an obstinate patient. Meanwhile, Meredith must choose between Derek and Finn, Addison drowns her sorrows in alcohol, and Cristina meets Burke's difficult mother.
Sometimes a Fantasy
episode S3.E3 october 2006Izzie returns to the hospital, but finds it difficult to go inside, and George is tired of Callie's presence at home. Meanwhile, Addison cannot seem to get rid of Mark, and Cristina tries to cope with caring for Burke.
What I Am
episode S3.E4 october 2006Meredith becomes a patient, and Derek and Addison are equally angry at Richard for allowing Mark to join the staff. Meanwhile, Izzie receives a visit from Denny's father, and Burke is plagued by doubt over his ability to return to surgery.
Oh, the Guilt
episode S3.E5 october 2006Guilt causes different actions in everyone, the interns are allowed to attend an M&M meeting, and Derek and Addison finalize things.
Let the Angels Commit
episode S3.E6 november 2006Izzie returns to the hospital under probation, and George tries to make amends with Callie. Meanwhile, Cristina's deletion of Bailey's name on Burke's OR board makes her assume he is against her, and Derek's irritating sister Nancy visits.
Where the Boys Are
episode S3.E7 november 2006Derek, George, Alex, Burke, Richard, Joe and Walter go on a camping trip. Meanwhile, Meredith assists Mark with gender reassignment surgery, Izzie avoids discussing her grief, Addison works with Callie, and Cristina feels Bailey's wrath.
Staring at the Sun
episode S3.E8 november 2006George must deal with his family's presence when his father is admitted. Meanwhile, Burke's secret is almost out, Alex tries to get close to Izzie again, and Richard comes to a decision about his marriage.
From a Whisper to a Scream
episode S3.E9 november 2006A traumatic car accident fills the ER. Cristina has a crisis of conscience about her deceptive teamwork with Burke, Izzie pushes the boundaries of her probation, and Callie tries to explain herself to George.
Don't Stand So Close to Me
episode S3.E10 november 2006Bailey is adamant that Burke and Cristina should be punished, Derek doubts his abilities, Izzie tries to take a stand against Mark's patronizing behavior, and Meredith deals with family in two very different ways.
Six Days: Part 1
episode S3.E11 january 2007As George's father's surgery approaches, he begins to realize how serious his condition is. Meanwhile, Izzie has to prove to Bailey that she is ready to scrub in on a surgery, and Meredith keeps running into her father.
Six Days: Part 2
episode S3.E12 january 2007George's father's surgery has left him very weak, Izzie's act of generosity backfires on her, Cristina and Burke continue their war of silence, and Meredith reaches out to her father.
Great Expectations
episode S3.E13 january 2007George deals with his grief, Cristina and Burke continue to ignore each other, Addison avoids Alex, and Izzie decides to help Bailey with a project. Meanwhile, Richard makes a decision which sends all the attendings scrambling.
Wishin' and Hopin'
episode S3.E14 february 2007A toxic patient wreaks havoc. Meanwhile, Bailey opens the free clinic, but the lack of patients makes Izzie question her investment. Meredith's mother is admitted again, and Cristina makes Burke wait for an answer.
Walk on Water
episode S3.E15 february 2007The interns each react differently to a mass-casualty incident. Meanwhile, George crosses the professional line with Callie, Cristina asks Burke to keep quiet about their engagement, and Richard dons a new hairstyle.
Drowning on Dry Land
episode S3.E16 february 2007Izzie fights to save her patient's life, George searches for the son of his patient, and Alex has to contend with the relatives of victims. Meanwhile, Meredith is unconscious underwater, with Derek her only hope.
Some Kind of Miracle
episode S3.E17 february 2007An unconscious Meredith interacts with some ghosts from her past while Richard, Burke and Bailey devise an unusual method of reviving her. A despondent Cristina leaves during her shift, and Derek speaks his mind to Meredith's mother.
Scars and Souvenirs
episode S3.E18 march 2007A Korean war veteran with a bullet lodged in his shoulder is admitted. Meanwhile, tensions escalate between Izzie and George, Callie reveals a big secret, Cristina contends with an old flame, and Alex continues to work with the Jane Doe.
My Favorite Mistake
episode S3.E19 march 2007The attendings face their board interviews. Meanwhile, Izzie seems to be the only one who remembers the night before, Derek is overly protective of Meredith when Mark offers her a surgery, and Callie's father pays a visit.
Time After Time
episode S3.E20 april 2007Meredith deals with her over protective stepmother, Cristina is caught between Burke and Marlow, and Derek fights to become Chief. Meanwhile, Alex continues the search for Jane Doe's identity, and Izzie's past comes back to haunt her.
Desire
episode S3.E21 april 2007The Chairman of Seattle Grace's board of directors is admitted, and the attendings vie for his favor, while the interns study for exams. Izzy and George are reminded of their infidelity, and Burke presses Cristina about wedding plans.
The Other Side of This Life, Part 1
episode S3.E22 may 2007Addison heads for warmer climate to figure things out, Meredith's stepmother visits the clinic, Cristina's perfect wedding is challenged when she and Burke's mothers visit, and Izzie tries to talk to George.
The Other Side of This Life, Part 2
episode S3.E23 may 2007Addison is pulled into the case of a high-risk surrogate mother, Meredith's stepmother develops a complication, Izzie struggles with George's decision, and Ava has surgery which may restore her memory.
Testing 1-2-3
episode S3.E24 may 2007The interns face their first year medical exams. With the interns busy, the attendings must do their own legwork, Burke appoints a new best man, Cristina writes her vows, and Callie grows suspicious of George and Izzie.
Didn't We Almost Have It All?
episode S3.E25 may 2007The wedding day arrives. Richard chooses the new Chief and Chief Resident, the interns receive their exam results, Callie drops a bombshell on George while Izzie pours her heart out to him, and Burke makes an important decision.
We Are Never Ever Getting Back Together
episode S10.E22 may 2014The doctors work together to operate on two sisters joined at the head; Cristina travels to Zurich where she deals with a blast from her past; Richard voices his concern over the hospital's allegiance with the Harper Avery Foundation.
All I Want Is You
episode S12.E10 february 2016As the hospital deals with Meredith's trauma, Callie and Maggie perform a risky, experimental surgery on Alex's 15-year-old patient against his professional opinion. Meanwhile, Owen and Nathan are still at odds with each other, and Maggie and Andrew's relationship continues to develop.
- A Hard Day's Night
- The First Cut Is the Deepest
- Winning a Battle, Losing the War
- No Man's Land
- Shake Your Groove Thing
- If Tomorrow Never Comes
- The Self-Destruct Button
- Save Me
- Who's Zoomin' Who?
- Raindrops Keep Falling on My Head
- Enough Is Enough
- Make Me Lose Control
- Deny, Deny, Deny
- Bring the Pain
- Into You Like a Train
- Something to Talk About
- Let It Be
- Thanks for the Memories
- Much Too Much
- Owner of a Lonely Heart
- Grandma Got Run Over by a Reindeer
- Begin the Begin
- Tell Me Sweet Little Lies
- Break on Through
- It's the End of the World
- As We Know It
- Yesterday
- What Have I Done to Deserve This?
- Band-Aid Covers the Bullet Hole
- Superstition
- The Name of the Game
- Blues for Sister Someone
- Damage Case
- 17 Seconds
- Deterioration of the Fight or Flight Response
- Losing My Religion
- Time Has Come Today
- I Am a Tree
- Sometimes a Fantasy
- What I Am
- Oh, the Guilt
- Let the Angels Commit
- Where the Boys Are
- Staring at the Sun
- From a Whisper to a Scream
- Don't Stand So Close to Me
- Six Days: Part 1
- Six Days: Part 2
- Great Expectations
- Wishin' and Hopin'
- Walk on Water
- Drowning on Dry Land
- Some Kind of Miracle
- Scars and Souvenirs
- My Favorite Mistake
- Time After Time
- Desire
- The Other Side of This Life, Part 1
- The Other Side of This Life, Part 2
- Testing 1-2-3
- Didn't We Almost Have It All?
- We Are Never Ever Getting Back Together
- All I Want Is You
Best moments10
- The doctors work together to operate on two sisters joined at the head; Cristina travels to Zurich where she deals with a blast from her past; Richard voices his concern over the hospital's allegiance with the Harper Avery Foundation.
- Meredith worries she did something wrong during a heart bypass, an error in a past procedure is discovered, putting a staff member's conduct under scrutiny, while a party thrown by Izzie to introduce her boyfriend becomes a fiasco.
- The victims of a workplace shooting are admitted. Izzie puts her job on the line to ensure Denny gets a new heart, Callie makes an effort with Meredith, and Addison is suspicious of Derek.
- Thanksgiving sends the occupants of Meredith's house in different directions: Meredith escapes to the hospital, George goes hunting with his family, and Izzie throws a dinner to which it appears no one is coming.
- Burke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.
- A traumatic car accident fills the ER. Cristina has a crisis of conscience about her deceptive teamwork with Burke, Izzie pushes the boundaries of her probation, and Callie tries to explain herself to George.
- Cristina is determined to get back to work, and despite not being fully recovered, she manages to crack an odd case. Meanwhile, Addison offers to help Bailey with a complicated surgery, and Alex receives important news.
- The Chairman of Seattle Grace's board of directors is admitted, and the attendings vie for his favor, while the interns study for exams. Izzy and George are reminded of their infidelity, and Burke presses Cristina about wedding plans.
- Derek and Addison are shaken by the arrival of a figure from their past. Meanwhile, Burke learns Cristina's secret, Izzie deals with a very unusual case, Meredith delves into her family's dirty laundry, and George pours his heart out.
- Derek, George, Alex, Burke, Richard, Joe and Walter go on a camping trip. Meanwhile, Meredith assists Mark with gender reassignment surgery, Izzie avoids discussing her grief, Addison works with Callie, and Cristina feels Bailey's wrath.
- We Are Never Ever Getting Back Together
- Shake Your Groove Thing
- 17 Seconds
- Thanks for the Memories
- Deterioration of the Fight or Flight Response
- From a Whisper to a Scream
- Deny, Deny, Deny
- Desire
- Yesterday
- Where the Boys Are