Chastain is flooded with concert goers following a stampede at a music festival grounds that leaves many in need of doctors.

When Bell makes the executive call to utilize Julian Booth's medical devices, rather than the hospital's usual products, Kit and AJ must stop their momentary feuding in order to team up against him. Elsewhere in the hospital, Conrad and Nic work to make a child's dreams come true after finding out his cancer has returned and the rest of the staff takes notice of Julian and Devon's new friendship.

Halloween at Chastain proves to be just as spooky as ever when Conrad is tasked with diagnosing a young woman admitted to the hospital with extreme night terrors. Meanwhile, Devon faces his first Halloween in the ER, Nic panics over her decision to bring her newly sober sister to Mina's epic annual Halloween party and Bell finds an interesting way to make use of his new assistant.

When patients from the hospital's prescription drug trial start suffering life threatening side effects, Nic fears that her sister Jessie may be in danger. As a result, she and Conrad work to convince Bell that these trials are not worth the risk. Meanwhile, Mina, Austin and Kit must set aside their competitive nature and work together on a patient whose health is quickly deteriorating and Devon uses Julian as the beta tester for a product he's designed.

Lane Hunter's victims and their families become outraged when she is released from prison. Bell, although responsible for posting Lane's bail and getting her released, continues to be tortured by her manipulation.

Conrad, Kitt, Mina and the Raptor work to save the life of a med student in need of a triple-organ transplant, drawing Bell back to the OR for one of the Chastain's riskiest surgeries yet. After the police find Julian's empty car in a nearby lake, Devon does some investigating of his own to find out what might have happened. Meanwhile, Mina and the Raptor hound Bell to halt his business with the risky medical device company, Quovadis, and Nic makes a rash decision regarding her sister.

When Conrad's attempt to surprise Nic with a lavish Valentine's Day dinner is foiled, he gives the reservation away to someone who could really use it. Mina and Devon distract themselves from all Valentine's celebrations by trying to figure out how their seemingly healthy neighbor has suddenly passed away. Meanwhile, Kitt gives dating advice to a sex-injured patient, Irving hits a crossroads in his not-so-secret relationship with Nurse Jessica, and Bell decides to celebrate the day in the OR.

Chastain picks up the pieces after the fall out with the corrupt medical device company Quovadis, leaving Marshall ready to charter new territory in the medical field, and Devon to finally discover the truth about what happened to Julian Booth. As Conrad and Alec team up to help a young gymnast experiencing mysterious symptoms, Nic focuses on her sister, who's back with their estranged father, Kyle, in tow. Meanwhile, Bell rushes to Kitt's aid when her ex-husband comes to the ER needing emergency surgery.

When Atlanta is struck by a severe snowstorm, Mina must perform a big surgery - without the help of The Raptor - to save the life of a young father, while Kitt and Bell get stuck babysitting the man's children. Nic and Conrad experience a disagreement with a patient's treatment, causing further strain in their relationship. Meanwhile, Devon teaches an important lesson about life and death to a first-year med student.

Devon grows concerned when a mother's complaints go unaddressed after her delivery, and pushes Bell to take drastic measures. Conrad is faced with breaking the news to Nic regarding Jessie's worsening condition. Meanwhile, The Raptor, Mina and Kit spring into action when a mother and son enter the ER with devastating injuries.

When the hospital has a severe blood shortage, Conrad must try every avenue to save a patient's life. Nic receives devastating news and is left worrying about her sister's health, while Mina and Devon work with a new anesthesiologist who is not what she seems. Elsewhere, Kit considers the future of her intertwining relationships and Bell has an encounter with a woman from his past.

In an effort to save Chastain, Bell considers selling the hospital to a conglomerate, but Kit tries to make him see that the negatives will outweigh the positives. With Conrad's help, Nic tracks down Kyle and pleads for him to reconsider donating a kidney to Jessie. Meanwhile, Mina voices her concern to Austin when Shira is assigned to Micah's surgery and Devon fights for the care of a patient whom the doctors suspect is uninsured.

The doctors of Chastain are surrounded by new rules and doctors, as Red Rock Mountain Medical takes over the hospital; Conrad finds himself in a dangerous situation when the construction for a neurosurgery center causes a gas explosion.

Intending to garner publicity for the hospital, Cain tries to recruit Bell and Kit on a dangerous surgery; the Raptor develops an emotional attachment to a patient; Mina's friend arrives with shocking news.

After a plane crashes in Atlanta, Devon is overcome by guilt at the thought that he could have prevented the tragedy. Bell, who was a passenger on the plane, makes it his personal mission to save the life of the man seated next to him. Meanwhile, Adaku returns to ask Mina a big favor, the Raptor struggles with telling his adoptive parents about meeting his biological father and Conrad and Nic consider risking it all to investigate a drug that might be linked to Jessie's death.

On National Nurses' Day, Chastain's nurses are severely understaffed and overworked, leaving them all feeling exhausted and underappreciated. Cain performs a dangerous surgery on a new patient he won in a game of poker. Meanwhile, Conrad discovers that his father has been administered the same drug that he fears played a role in Jessie's death, The Raptor comes face-to-face with his birth mother for the first time and Irving attempts to take the next step in his relationship with Jessica.

Conrad comes under fire when a former patient files a malpractice lawsuit against him, putting Bell in a difficult position with Red Rock. When Devon discovers that his VIP patient has a life-threatening brain condition, the doctors ban together to perform a risky surgery. Meanwhile, Mina discovers that Adaku has a dangerous heart condition that puts her and the baby at risk, and Kyle forms a personal relationship with a patient.

On Devon's last day as an intern, he and Conrad are faced with a moral dilemma over a suicidal patient who is in need of a liver transplant. When Bell discovers that Cain is keeping braindead patients alive in order to boost his survival rates and add to Red Rock's profits, he decides to take matters into his own hands. Meanwhile, Adaku goes into early labor, causing a strain on her heart and Mina is left in doubt over how to best handle her care.

Cain feels disrespected by Logan Kim when he is left out of a major decision regarding Conrad. Meanwhile, the doctors work together to try to save the lives of two big Red Rock donors who were involved in a jet skiing accident. Then, Irving and Devon realize that three of their patients, all with different symptoms, could actually be triggered by the same thing. Also, Bell's supplement company proves to be more lucrative than anyone anticipated, but an unexpected snag could put it in jeopardy.

Conrad finds himself caught between his duties as a doctor and his loyalty to Kitt, when he discovers that her son-in-law may be suffering from a serious disease. While moonlighting at a long-term care facility, Devon and Nic make a shocking discovery about a former patient who fell victim to Cain's manipulative practices. Meanwhile, after jumping into a new opportunity as a TV doctor, Bell is left without any surgeries and The Raptor brings him in to help on an important case.

When Cain becomes aware of an emergency situation breaking out at the hospital, he recruits Ezra to help keep it under wraps. Also, Nic works to come up with a support system for a patient in need of a lung transplant. Meanwhile, Kitt's son-in-law's condition continues to worsen.

Just when Derek's condition seems to be improving, a severe complication arises, causing Kitt to fear that he may be the latest victim of Cain's cover-up. When Cain's former girlfriend is admitted to the hospital for surgery, the doctors finally get a glimpse into his personal life. Meanwhile, Conrad fills in Marshall on the emergency situation facing the hospital and Mina and The Raptor work on saving the heart of a salsa dancer.

During the COVID-19 pandemic, the staff of Chastain does their best to treat the overwhelming number of patients that they face while also trying to protect their loved ones; Conrad and Nic get married.

When Cain's elected surgery patient returns with complications, Mina and Raptor butt heads over how to handle the situation; Conrad and Devon treat a local Congresswoman.

When Cain tries to be a hero at a crash scene, he is struck by a car, causing Chastain's doctors to put aside their personal issues to try and save his life.

The staff works to diagnose a mother and daughter with a mysterious illness. Devon deals with a surprise visit from his mother. Mina makes a surprise proposal.

Chastain is being dismantled, Doctors and surgeons are transferring and patients are panicking. Nic and Conrad announce they're going to be parents when another tragedy strikes.

The hospital now a public hospital tries to adjust to the changes. When one of the surgeons who is scheduled to perform an important surgery decides to quit because of his pay reduction, they try to find another. Bell asks his step son to do it. And Nic who is still recuperating is visited by her friend a former nurse practitioner who was let go because she performed an unauthorized surgery and who has a tense relationship with Conrad. When something happens to Nic her friend offers to help and Conrad is not sure if she should. Meanwhile, the hospital looks for a new CEO.

When Conrad gets a call from his former army commander who is stranded and wounded in the forest, the trip to save him brings lots of old emotions to the surface. Devon and Kit treat a patient who suffers from sickle cell anemia and encourage her to have a hip replacement to help treat her pain. Meanwhile, The Raptor is pulled away in the middle of an intense surgery, Mina is left to put her skills and finish the surgery on her own and Bell works on reconnecting with his stepson (guest star Conrad Ricamora) after helping him get hired at the hospital.

On Nic's first day back at Chastain, the man who attacked her is admitted to the ER, causing her to confront her trauma head-on. Cain, now in recovery, is self-conscious of his physical state and sets his eye on taking down Mina. Meanwhile, new intern Leela, both struggles and shines throughout her first day, causing Devon and Conrad to wonder if something bigger is going on.

Conrad and Bell treats the woman carrying Jake's future baby. Devon contemplates his love life. Mina receives a call that causes her to make a bold decision about her future.

Just when Mina and The Raptor can see their future together, an unexpected complication throws a wrench in their plans. Meanwhile, Cain faces a harsh reality when Kit gives him the opportunity to prove he is ready to return to the OR. Then, Devon presents Rose with a groundbreaking clinical trial that could help her battle with Sickle Cell Anemia.

When a tornado touches down in Atlanta with Chastain directly in its path, the entire staff goes into crisis mode. Conrad and Nic work on an injured EMT and Devon and Leela become trapped with a man who has severe head trauma, causing them to operate with limited medical supplies. Meanwhile, Bell pulls The Raptor and Dr. Wong onto a case involving a young cancer patient in need of a very risky surgery and Cain gets assigned a new resident.

With Nic's due date steadily approaching, she and Conrad plan a relaxing day off, but their plans are interrupted when a patient with a medical mystery sends them rushing back to Chastain. Devon stays by Rose's side as she starts her clinical trial and things take a turn for the worse. Meanwhile, Kit is under pressure to bring Chastain out of debt.

The wait is over as Conrad and Nic welcome the arrival of their baby girl. Meanwhile, Raptor's life begins to fall apart and he is forced to turn to Cain for help. Also, Devon and Bell work together on a complicated surgery that may allow them to save multiple lives. Then, Kit tries to deal with the moral repercussions of financially saving Chastain.

A cyberattack sends the hospital into a tailspin and Kit has to decide whether to pay the ransom. Conrad has to balance work with being a new dad. Devon and Leela debate where their relationship is going.

When Devon is found unconscious on the roof, the staff frantically retrace his steps to determine what happened. Billie fights with her son over a drug overdose. Bell helps Kit vet a new neurosurgeon.

An accident brings a familiar patient into the ER, the doctors must face the reality of how to proceed with the best care while questioning every decision. The Raptor and Leela treat a patient dealing the long-term effects of COVID

In trying to find a way to channel his emotions, Conrad puts all his effort in looking for answers. Raptor has a run-in with the police that ends up taking a surprising turn. Meanwhile, Leela begins noticing problems with a surgeon who has been Bell's mentor.

While looking for a distraction on Halloween, Conrad treats a group of witches who send the ER into chaos. Also, Devon treats a patient who thinks he is being haunted by ghosts. Meanwhile, on the way back from his vacation, Bell picks up a hitchhiker who is not what he seems to be.

Conrad brings a patient into the hospital who causes a high security crisis. An MMA brawl sends a well-known fighter to Chastain and all hands are on deck. Meanwhile, Bell and Raptor vie for the same position at the hospital, and Leela gets a visit from her sister.

A new group of interns start their first day with Devon at Chastain. Kit and Bell try to convince Conrad to come back to Chastain. The Raptor's mother ends up back in the ER. Leela and Padma deal with an unexpected visit from their parents.

Kit hires a surgical coach to watch over Bell and Raptor and help them brush up on their skills. Upon receiving attention from multiple women at the hospital, Conrad contemplates jumping back into the dating scene. Devon works with an elderly couple.

Conrad mentors Trevor whether to treat a patient whose luck seems to have run out.

When the first day of Kit's experimental Flight Go team programme sends Conrad out into the field, he builds a new relationship with a fellow doctor along for the ride; Devon works with Trevor on a patient with a mysterious fever.

A case turns personal for Conrad when the donor-recipient of Nic's heart is admitted to the emergency room; Bell is faced with a devastating diagnosis that causes him to make a heartbreaking decision.

Conrad and Cade examine a child showing signs of abuse. Devon and Leela encounter a woman having trouble breathing. Meanwhile, Bell eyes an open seat on the State Medical Board and Billie decides it's time to confront her past.

A tragic accident occurs at Jessica's sister's gender reveal party. Conrad, Irving and Trevor work on an influencer whose life is in danger due to a risky cosmetic procedure.

When Billie's past mistakes are exposed, the team struggles to find a way to support her. The nursing shortage hits Chastain. A simple cleaning job goes horribly awry.

As his clinical trial begins, Devon treats his first patient with a revolutionary medical fluid that doesn't go as planned. Meanwhile, an overdosed John Doe is rushed to Chastain, leading Conrad straight into a much bigger scandal than he expected. Then, a shocking secret regarding Cade's past is discovered.

Conrad and The Raptor help out an old friend whose heart problems reveal a bigger issue than they anticipated. Bell confronts the Medical Board about the cases he's been investigating.

Conrad treats one of Gigi's classmates whose stomach ache turns much more serious. Devon takes several interns to the senior living facility. Leela uncovers unsettling news.

When Conrad confronts a pharmacy owner about fraudulent prescriptions, she turns up dead. The ER is sent in to chaos when both families on the end of a street racing accident are present.

With AJ on leave to take care of his mother, the hospital scrambles to organize without him. A camping trip leaves a patient with a fatal disease no one can diagnose.

Conrad and Cade work with a Medicare patient who sheds some light of prescription fraud. Leela works herself to the brink of exhaustion.

When one of the doctors is shot outside the hospital, the ER is put into lock down; a patient learns he is unable to receive a transplant due to his vaccination status; Devon and Leela try to juggle the new dynamics of their relationship.

A young boy comes into the hospital with a rare disease which leaves his bones incredibly fragile; with his clinical trial officially being declared a success, Devon has some huge decisions to make about the future of his career.

Conrad contemplates his future; Devon is presented with an amazing career opportunity.

When Padma's pregnancy takes a dangerous turn, the doctors come together to find a solution. Conrad makes a decision regarding his love life. Devon leads his own clinical trials at Chastain.

A brawl breaks out at a polling station.

A gunshot victim enters Chastain.

Conrad spends the day with Gigi.

A college professor comes into the emergency room and Conrad realizes it's a former patient from when he was an intern. Devon ends up admitting a man who swears he knows the answer to eternal life.

Kit and Bell say "I do".

Conrad and Raptor help a death row inmate.

After a teenage boy is taken into Chastain for falling unconscious from a suspicious pill, Conrad takes action to find the boy's brother before he meets the same fate; Dr. Bell deals with being served court papers from a former patient.

Hawkins, Pravesh and Feldman deal with a couple of guys who run a home exotic zoo. Pravesh is working hard to get a medical prototype surgically installed in a patient. Bell deals with yet another issue with his MS diagonals.

Conrad comes face to face with Nic's dad when he comes to Chastain with an extremely low heart rate. Billie advises her patient against surgery, but the patient's family ignores her recommendation.

A famous cardiothoracic surgeon comes into Chastain after experiencing heart pain. Kit breaks the news that the emergency room can no longer accept trauma patients due to budget cuts.

The doctors rush to treat patients after a heavy storm causes a devastating helicopter crash.

Conrad is pulled away from celebrating Gigi's birthday when Sammie comes into Chastain with 104 degree fever. Kit must call in a favor. A donor heart arrives for the governor.

The hospital now a public hospital tries to adjust to the changes. When one of the surgeons who is scheduled to perform an important surgery decides to quit because of his pay reduction, they try to find another. Bell asks his step son to do it. And Nic who is still recuperating is visited by her friend a former nurse practitioner who was let go because she performed an unauthorized surgery and who has a tense relationship with Conrad. When something happens to Nic her friend offers to help and Conrad is not sure if she should. Meanwhile, the hospital looks for a new CEO.

On National Nurses' Day, Chastain's nurses are severely understaffed and overworked, leaving them all feeling exhausted and underappreciated. Cain performs a dangerous surgery on a new patient he won in a game of poker. Meanwhile, Conrad discovers that his father has been administered the same drug that he fears played a role in Jessie's death, The Raptor comes face-to-face with his birth mother for the first time and Irving attempts to take the next step in his relationship with Jessica.

After a teenage boy is taken into Chastain for falling unconscious from a suspicious pill, Conrad takes action to find the boy's brother before he meets the same fate; Dr. Bell deals with being served court papers from a former patient.

A famous cardiothoracic surgeon comes into Chastain after experiencing heart pain. Kit breaks the news that the emergency room can no longer accept trauma patients due to budget cuts.

Conrad and Cade work with a Medicare patient who sheds some light of prescription fraud. Leela works herself to the brink of exhaustion.

Chastain picks up the pieces after the fall out with the corrupt medical device company Quovadis, leaving Marshall ready to charter new territory in the medical field, and Devon to finally discover the truth about what happened to Julian Booth. As Conrad and Alec team up to help a young gymnast experiencing mysterious symptoms, Nic focuses on her sister, who's back with their estranged father, Kyle, in tow. Meanwhile, Bell rushes to Kitt's aid when her ex-husband comes to the ER needing emergency surgery.

Intending to garner publicity for the hospital, Cain tries to recruit Bell and Kit on a dangerous surgery; the Raptor develops an emotional attachment to a patient; Mina's friend arrives with shocking news.

Just when Derek's condition seems to be improving, a severe complication arises, causing Kitt to fear that he may be the latest victim of Cain's cover-up. When Cain's former girlfriend is admitted to the hospital for surgery, the doctors finally get a glimpse into his personal life. Meanwhile, Conrad fills in Marshall on the emergency situation facing the hospital and Mina and The Raptor work on saving the heart of a salsa dancer.

Conrad finds himself caught between his duties as a doctor and his loyalty to Kitt, when he discovers that her son-in-law may be suffering from a serious disease. While moonlighting at a long-term care facility, Devon and Nic make a shocking discovery about a former patient who fell victim to Cain's manipulative practices. Meanwhile, after jumping into a new opportunity as a TV doctor, Bell is left without any surgeries and The Raptor brings him in to help on an important case.

The doctors of Chastain are surrounded by new rules and doctors, as Red Rock Mountain Medical takes over the hospital; Conrad finds himself in a dangerous situation when the construction for a neurosurgery center causes a gas explosion.