Sam helps Josh battle his health insurance company; Ainsley Hayes encounters her firebrand boss and hostile colleagues; Abby gives the President some good news about his health; C.J. discovers a retiring General intends to publicly criticize the president.

Sam meticulously prepares a speech for the President to give to the environmental lobby, but Toby wants to sneak in some criticism of their failure to condemn environmental terrorism. Leo tries to convince the President to support his pet project - a missile defense shield - despite its continued failure to produce results, and the fact that it likely contravenes an anti-ballistic missile treaty. Several countries including Great Britain have sent new ambassadors to Washington to be recognized by the White House. C.J. travels to New York on a delicate mission to ask for a political favor from a comedian.

President Bartlet is fighting a war on two fronts as he tries to rescue hostages in Colombia and deal with explaining to his wife why he's breaking his word to her by running for a 2nd term.

With hypothetical polling numbers showing them it will be political suicide, staffers prepare to announce the President's condition. As they do, a military crisis flares up in Haiti and Josh faces off against two senators who are against the Government's tobacco industry suit. But as badly as the day seems to be going, a tragedy will come from a car wreck at 18th and Potomac that will affect everything.

The West Wing goes under lock down as a suspected terrorist is found to be working at the White House. Stuck with a group of high school students who were visiting the White House, the staffers, President Bartlet, and the First Lady all debate the issues regarding terrorism. Meanwhile, Leo sits in on the questioning of the terrorist suspect and learns a lesson about our perceptions of terrorists.

With the staff all bickering with one another in Manchester, especially adversarial speech writers Toby and Doug, who angrily disagree about whether Bartlet should make a public apology for lying about his MS, and with the president sniping at everyone, the second-term announcement speech is locked. Abby ultimately forgives the president for deciding to run again without discussing it with her, and he ultimately apologizes to the staff in private for keeping his condition from them, which they expect will soon lead to a whole slew of grand jury subpoenas.

While the W.H. is hosting a gala dinner for Nobel Prize winners, Leo and the president learn of a suicide bomb in an Israeli cafe that took the lives of two American students in Tel Aviv for a soccer match, and the staff attempts to manage the president's first veto, of a House bill eliminating the estate tax, and the threat of an override the same night. Sam and Toby first try to sway a contentious Dem. From Tennessee who wants a whole list of farming and ranching concessions in exchange for his vote and three proxies; after a pep talk from Leo, they devise a substitute plan that may prove even more effective, if it works. Josh takes the governor of Indiana into a private meeting to determine if the man plans to challenge Bartlet in Democratic primary. C.J. takes heat from a smarmy Dallas entertainment reporter who is in town for the Nobel dinner but winds up having to cover the veto and override vote, but after the reporter embarrasses her during a live stand-up, C.J. one ups the woman in front of the press corps. Later, Sam, Toby and Josh try to help the president decide what to say to the parents of the two murdered students.