Special prosecutor Clem Rollins announces the grand jury subpoenas in the case of president's failure to disclose his MS to the public, and the list includes pretty much every West Wing staffer and Bartlet family member; Sam and Connie meet with an important Latino activist from Calif. who is considering supporting a primary challenger to Bartlet; C.J. convinces everyone that the special prosecutor is too reasonable, and that the W.H. needs a "better enemy" in the investigation, prompting the staff to provoke a Congressional inquiry.

After a fatal shooting in Texas, the president asks Hoynes to go down there and speak out for gun control, in spite of his history opposing it. Donna makes a gaffe in front of the Congressional committee. Leo argues with an old friend about the creation of an international war crimes tribunal.

In an episode dotted with flashbacks, Leo and his attorney Jordon Kendall (Joanna Gleason) face a Congressional inquiry into whether the president lied to the American people regarding his MS, but this particular day of hearings concerns itself more with Abby and her secretly medicating Jed, and later with Leo's having fallen off the wagon during the campaign (a politically motivated Republican rep on the committee witnessed Leo drunk in his room three days before the nomination); we see the meeting in which Leo talked N.H. Governor Bartlet into running for president, introducing his idea, "Bartlet for America", on a cocktail napkin, which the president later frames and returns to Leo as a gift in thanks for all he's done for the president over the years; Cliff Calley, Donna's boyfriend and special counsel to the judicial oversight committee, asks the committee chair to halt the inquiry before the rep can compel Leo to admit his personal transgression; Leo asks Jordon to Xmas Eve dinner.

In a private, late-night meeting, Cliff Calley informs Leo and Jordon he has negotiated a settlement in the Congressional witch hunt over Bartlet's MS: Bartlet can accept a joint congressional censure (House Concurrent Resolution 172, or H.Con. 172); Leo initially refuses to bring it to the president, insisting it will devastate the president and affect him for the rest of his life, but he does mull it over, and consults with Josh and repeatedly with Jordon about it; Josh begins his romantic pursuit of women's issues advocate Amy Gardner, but flubs it a couple of times while she continues dating other men.

Back in Washington briefly, Josh visits the White House and is surprised to discover that as a campaign manager he is no longer part of the inner circle in an administration that wants to remain neutral in the Democratic primary. Toby is the focus of some concern after being more withdrawn than usual and also because he is nursing a cut on his face that he doesn't want to talk about. Charlie tells Kate that a guy at his gym has been asking about her, but she's unsure if she's ready to date again. A multi-state water rights fight pitches C.J. against lobbyist Cliff Calley, who proves to be both infuriating and intriguing. Josh and Donna are both suspicious when far-left Senator Rafferty joins the race, obviously as a spoiler candidate.

The Speaker of the House deliberately calls a vote on stem cell research when he knows that Democrats will be away from Washington; Donna, Cliff, Matt, and Josh must put aside their differences to foil the plan. Kate is shocked when a minor hunting mishap on the Canadian border threatens to become a major international incident. A Japanese economist who has been President Bartlet's arch-rival since college is attending a formal dinner at the White House, creating a potentially explosive situation. Toby tries to avoid meeting with a group of middle school children who want a constitutional amendment lowering the voting age.

Rumors circulate in Washington yet again about the state of Fidel Castro's health. As C.J. begins to look into the issue she uncovers some dark secrets regarding the United States' relationship with Cuba which appear to involve Leo, the President, and Kate Harper. Despite how closely guarded and potentially explosive this information is, a startlingly large number of government agencies and officials appear to know bits and pieces of the story. This results in undercover political maneuvering to avoid what is expected to be an enormous political disaster. Meanwhile, Charlie calls in different professionals to deal with a suspected termite problem in the White House.