Dr. Romano seizes control of the ER and manages to offend everyone. Dr. Kovac asks Dr. Corday's help in the quest to bring a sickly Croatian boy to the U.S. for medical treatment.

A psychotic patient threatens Abby. Dr. Weaver suspects a woman poisoned her own baby. Dr. Romano continues to make rash judgments.

Dr. Carter tries to prevent a grieving gang member from going after vengeance. Dr. Kovac races against time to save a Croatian boy's life. A baseball player gets treatment for a heart problem.

On his return to Chicago, Carter gets a downright chilly reaction from Abby who asks him to return her apartment key. At work, they tip toe around one another, neither really willing to discuss their feelings. A new med student, Neela Rasgotra arrives for her ER rotation. Dr. Pratt is paying too much attention to her for Dr. Chen's taste. A woman passes out at the wheel of her car severely injuring herself and the three children in the car with her. Neela makes a good call in the case. Carter treats a man whose HIV has become full-blown AIDS. The ER itself is a bit chaotic due to major reconstruction. The ER desk receives a call from Africa saying that Luka Kovac has been killed. Carter decides to return to the Congo to retrieve his body.

To everyone's amazement, Lewis makes a date to share a home-cooked dinner with the elderly Ben Hollander, her depressed patient who is going blind.

On Thanksgiving Day, a helicopter crash outside the ER leaves several injured. Alex tries to bring Sam and Luka together.

Carter misses his pregnant girlfriend who has returned to Africa. A family of four is rushed to the emergency room after suffering carbon monoxide poisoning from their faulty furnace--forcing the claustrophobic Neela to accompany a newborn baby into an extremely uncomfortable hyperbaric chamber.

Carter defends his protégé Neela when Weaver and other doctors rate the residents. Carter urges his student to be more proactive in the emergency room, but Neela goes too far in treating a patient with a brain injury--and sympathetic Gallant errs further by falsifying a medical report. Meanwhile, Chuck protects pregnant Lewis from a pervert who is harassing her. Kovac treats a disoriented young boy whose dad fears that tests will reveal he is not the boy's biological father. Chen is unable to find a caretaker for her combative father. And Corday is uneasy about dating two men at once.

It's a busy Fourth of July and Carter is the only attending working.

Jules 'Ruby' Rubadoux is back in the ER. He's still angry with Carter about the death of his wife.

Morris is named the new chief resident, which makes nobody really happy, except Morris. Meanwhile Luka and Sam are having communication problems, Carter gets a promotion Susan really wanted and Ray finds out a 14-year old who always comes in for free drugs has been raped.