Dr. Anspaugh's 13-year-old son is brought in and Anspaugh asks Mark to look after him. Another old lady who has been raped is brought in.

Kerry starts to doubt the methods of Synergix. Carter tries to help his cousin beat his drug addiction. Jeanie becomes Scott Anspaugh's part-time caregiver.

Mark finds out Cynthia has moved. Carter's cousin Chase is brought in because of a heroin overdose. Doug and Kerry clash after she found a flaw in his study.

Dr. David Morgenstern returns after a six-month absence recovering from his heart attack. His new outlook on life however has Kerry Weaver questioning his abilities. Elizabeth Corday decides to start a study on the use of artificial blood in the ER, but the only problem is that she fails to discuss it first with Rocket Romano. Doug Ross decides to apply for an ER attending position. Scott Anspaugh suffers a major relapse. Anna Del Amico is confronted by an irate husband who wants his ill wife to terminate her pregnancy. At the free clinic, Carol Hathaway has to deal with the case of an underage high school student who is sleeping with her 40-year-old teacher. Peter Benton hits a pedestrian with a car but Carter helps him out with an important piece of information.

When a compatible bone marrow donor cannot be located, Scott Anspaugh agrees to undergo a new round of chemotherapy, even though there appears to be little point. Doug Ross suggests to Jeanie Boulet that Scott may have agreed to the therapy because of her. Mark Greene has taken on the task of organizing the annual ER banquet only to find that Jerry, on whom he had been relying for much of the preparation, hasn't quite delivered. John Carter confronts his grandmother when he learns that she has cut off funding for Carol Hathaway's free clinic. In the OR, Peter Benton has a major confrontation with Dr. Morgenstern, pushing him aside and taking over an operation. Greene and Weaver criticize Doug Ross over his handling of a sick child and her mother.