Claire has taken a liking to her friend Edie but is having difficulty coming to terms with her emotions. With Vanessa suspicious, Rico decides to tell Sophie he can't come by anymore. She's at her manipulative best and he can't bring himself to break away. Vanessa follows him and assumes the worse when she sees her. Nate and Brenda have been sleeping together but he also goes on a date with a fellow worker from the pet retreat. George and Ruth's relationship is strained and he invites her on his annual fossil hunt. Their outing doesn't go well and they end up at her sister Sarah's house. Sarah's overcome her addiction but Ruth realizes she may have more in common with her sister than she would like to admit. Keith is on tour with Celeste who takes them to a gay bar.

While trying to reach the newspaper on the sidewalk, Samuel Wayne Hoviak, who was the best high-school friend of Nate, falls and his truck run over him. In the funeral service, Nate meets their other former best friend, Tom Wheeler; they recall their adolescence and realize that they are getting up. The bitter and deranged Ruth has no patience with George, and they receive his daughter Maggie. David proposes Claire to donate her eggs for the baby of his own with Keith, but she refuses. Claire feels her art rejected by the owner of a gallery and Billy misses his former personality. Rico dates Sharon and does not understand her hint that she does not want to see him again. Brenda begins an internship in a free clinic and does not support her first day, seeking Margaret's influence to help her to find a better place to work.