The investigation of the death of a petty con man/drug mule leads the CSI team to Brass' daughter Ellie.

While performing on the stage, the comedian Dougie Max dies. Grissom, Catherine and Capt. Brass investigate the case and Grissom and his team conclude that he was poisoned by the expensive bottled water Innoko. When a teenager dies in a convenience store, Warrick is assigned by Grissom to investigate the case, and soon he finds that the youngster had drunk Innoko water. Grissom finds that the bottles came from the same lot, and was not a tampering case. Meanwhile, Brass asks Nick to reopen the case of Shelley Stark, who died in an accident in a bathtub and Brass did not call any CSI investigator. He has just seen her husband with a hot woman driving a Ferrari and he is intrigued, since the man was inconsolable. Nick and Sara reopen the case and find new evidences.

Although living in a well-protected gated community, the couple Mike and Laurel Trent are executed in front of their house by two masked killers. They were owners of the famous Acid Drop club among other properties. Grissom notes that Laurel was dragged out of the car, but Mike was dragged down the driveway in a place where everyone could see him. The whole team is assigned to investigate the case since the real state is large. Soon they find that the jewels have been robbed and Laurel had made porn films in the past with the production of Drake the Snake. Catherine goes to the Acid Drop and interviews the manager Chris Bezich first and Drake, who is bartender, later. Their further investigation shows that Mike's former partner Kyle Goode is suing him in the justice. When Grissom is summed to a murder case in an apartment, he finds evidences that will help him to resolve the case.