Harry investigates a case of hit and run where the victim was a 16 year old boy from the nearby housing estate. Working with Sgt. Susan Fenn, they attempt learn if this was an accident or intentional. Harry takes quite a liking to Susan and is shocked by a sudden turn of event. Leo examines a death resulting from a house fire where the lady of the house died. He is puzzled at why she was unable to leave and the police immediately suspect the husband, who was in a nearby park with the children, of murder. Nikki looks into the case of a young woman who collapses at her hen night. She had recently had minor surgery and was taking pain killers, but there is surprising information to be found about her background.

The pathologists busy week continues with a variety of cases. Nikki examines a death in a telemarketing office. Several workers were vying for promotion and the police suspect foul play. Harry deals with the case of a professional footballer who committed suicide. He realizes there is a link to another case he is working on. Leo deals with the case of a drunk who died on a bus. There is little information about the man and the case becomes more of a puzzle when the autopsy reveals that he wasn't drunk at all.