Jane goes into labor, causing conflict between Rafeal and Michael. Meanwhile, Xo and Rogelio try to make it home on time to see the baby. Petra makes a discovery of her own.

When a slot opens up in the graduate program that Jane has been waiting for, she is faced with her first big motherhood dilemma - leaving Mateo sooner than expected. Rafael is still reeling from Petra's news as he tries to help plan Mateo's baptism with Jane. Xo helps Rogelio confront his past even though it makes Xo uncomfortable. Meanwhile, Michael takes some advice from Rogelio about how to handle Jane, but it is easier said than done for him.

Jane's latest parenting obstacle is sleep training Mateo, a struggle that has the Villanueva woman divided on what is the best method. At the same time, she is beginning her new job as a TA and is faced with a class full of basketball players looking for an easy A. Petra confesses all to Rafael and is determined to put her mother away for good. Rogelio's mother Liliana comes for a visit and reveals a forty year old family secret. Meanwhile, Michael discovers the truth about Luisa's mother and new information about Rafael's mother.

Jane (Gina Rodriguez) has a specific idea of how she wants to celebrate her bachelorette party, but when Xo (Andrea Navedo) and Lina (guest star Diane Guerrero) get involved, nothing goes as planned. Michael wants to enjoy a night out with his friends, but things get awkward when his future father-in-law, Rogelio (Jaime Camil), tries to plan the perfect bachelor party. Rafael (Justin Baldoni) is still trying to figure out what his half-brother Derek (guest star Mat Vairo) motives are and what he knows about their mother. Meanwhile, Petra (Yael Grobglas) gets a surprise of a lifetime. Ivonne Coll also stars.

The Villanueva women have a tradition for Mother's Day and Jane (Gina Rodriguez) is excited to get to participate in her first one as a mom. However, their plans are thwarted when Petra (Yael Grobglas) invites everyone to a brunch instead. Jane's TA position is put into jeopardy when a mysterious ad appears in the college newspaper. Rogelio (Jaime Camil) is hurt when Dina (guest star Judy Reyes) doesn't invite him to her birthday party, so he asks Jane to help in an unusual way. Rafael (Justin Baldoni) finds himself in big trouble thanks to his half-brother. Meanwhile, Xo finds herself in a compromising position. Ivonne Coll and Brett Dier also star.