After Niles is depressed about his life as a butler, he begins to act strange and while he is cleaning, he drops a piece of paper containing a list of items that convinces Fran that Niles is possibly a murderer due to his recent strange behavior and the contents of his list. A search of his room confirms her suspicions. During a stormy night, Maxwell takes the children out for dinner leaving Fran and Niles alone. Niles approaches Fran and she thinks Niles is about to murder her. He confronts Fran about how she knows what he is up to when in fact he is simply writing a play.

Val has two tickets for Michael Bolton's album premiere party, so Fran asks Mr. Sheffield on a romantic date. She's terrified with a weird rash that appeared all over her body, and rushes to the hospital after Mr. Sheffield decides to take her up to a room for their first intimate night together. She gets a cortisone shot from an inexperienced doctor, which makes Fran swells like a balloon. The romantic night is ruined, thanks to Sylvia's squash-filled pasta that gave Fran the allergic reaction.

Fran's devastated after hearing from Dr. Reynolds she was never pregnant at all, that it was a false positive. Maxwell keeps hiding her pregnancy tests to avoid further sadness, and even invites Fran and her relatives to join him on his special appearance on the Hollywood Squares. Val, Sylvia and Yetta advise Fran to go see a herbalist to help Maxwell's swimmers. At the herbal store, Fran buys a special shake that will help Maxwell's little swimmers swim faster and some special cookies that will make them hot for each other. The shake doesn't help, so Dr. Reynolds prescribes hormones for Fran, who also buys an ovulation kit. Her timing couldn't be worse when she starts ovulating right when Maxwell is up on the squares. But nothing that Whoopi Goldberg's dressing room can't fix. Meanwhile, C.C. and Niles accidentally eat the special cookies and feel hot for each other, and Val quits her brightness pills because it was making her too gassy.

While still shocked about finding out Niles and C.C.'s secret affair, Fran and Maxwell worry about something else: it seems like Max's biggest chance to beat Andrew Lloyd Weber at the Tonys is going to be wasted, since he can't get a decent play script and thus won't open any new shows. Fran shows him Yetta's old love letters she wrote to a waiter she met on the ship that brought her from Romania, but Maxwell doesn't think those will make a good play. The letters get accidentally sent to Andrew Lloyd Weber's office and he tries to buy the play rights for Yetta's letters, but Maxwell steps in – thanks to Sylvia's power of attorney – and opens one of the most exciting plays of the season!