Captain Jack Sparrow searches for the Trident of Poseidon to rule the sea while being pursued by old rival Captain Salazar and a crew of deadly ghosts who have escaped from the Devil's Triangle.

After his mother drug overdose, 17-year-old Joshua "J" Cody (James Frecheville) asks his estranged grandmother, Janine "Smurf" Cody (Jacki Weaver), for help, and she invites him to move in with her. Smurf is the affectionate matriarch of a Melbourne crime family that uses her home as a base. Her home is also being watched by cops who are looking for the oldest son, Andrew "Pope" Cody (Ben Mendelsohn), who is in hiding. The volatile middle brother, Craig (Sullivan Stapleton), deals drugs successfully enough to have bought the house for his mother. The youngest brother, Darren (Luke Ford), follows the lead of his siblings, while family friend "Baz" (Joel Edgerton) leads the gang, which specializes in armed robbery.