Ethan finds himself at odds with Natalie and Sharon as he treats a teenage mother who abandoned her newborn baby in an alley.

Sharon is visited by the Department of Homeland Security regarding two airplane stowaways who are brought to the hospital with major injuries.

Sharon must decide whether to put her job on the line for a patient in need.

Dr. Halstead (Nick Gehlfuss) and Sharon Goodwin (S. Epatha Merkerson) deal with a husband intent on harvesting his recently deceased wife's eggs, but soon discover some vital information that surprises everyone. Dr. Charles (Oliver Platt) is brought in by Dr. Choi (Brian Tee) to aid a patient who is trying to remove his own arm from his body because he feels like it doesn't belong. Nurse Sexton (Yaya DaCosta) befriends the father of a child who is rushed into the hospital after swallowing magnets - a situation that Dr. Rhodes (Colin Donnell) and Dr. Manning (Torrey DeVitto) are concerned could present dangerous complications. Meanwhile, Sarah Reese (Rachel DiPillo) finally learns about where she will do her residency, but has last-minute second thoughts.

April and Dr. Halstead treat an alcoholic homeless man with a broken leg.