On his deathbed, Jeffrey Roundhill confesses to having killed his wife Evelyn some 8 years before and tells Murdoch where to find her remains. Dr. Grace confirms the identity of the skeleton as that of Mrs. Roundhill but the manner in which she died doesn't match Roundhill's statement. Further investigation reveals that Roundhill was actually in Winnipeg on the day his wife disappeared. Julia recalls a case, that of Amelia Thompson, who was killed just as Roundhill describes. At the time, Murdoch was convinced that her husband was responsible for his wife's death. Could the two men have killed each other's spouse? Meanwhile, George Crabtree hasn't seen much of Emily lately and takes Leslie Garland to task for interfering in their relationship.

Honeymooning in England, Crabtree and Effie find a dead hotel guest while Murdoch investigates an apparent suicide.