Lt. Daniels puts his team together but the extra help he's asked includes several less than stellar officers. It also includes McNulty, who is obviously in the doghouse. When one of the witnesses against D'Angelo Barksdale is found dead, McNulty and his homicide partner 'Bunk' Moreland bring him in for questioning. They have no evidence that he had anything to do with the killing but their instincts tell them otherwise. When news of the witnesses death hits the press, Major Rawls is convinced that McNulty is again responsible. Three of the newly assigned detectives, Hec, Prez and Carver decide to go to the towers and flex a little muscle only to have it turn into a major disaster.

Avon takes care of Omar's man Brandon but Wallace, who saw Brandon in the arcade, isn't too comfortable when he sees what they've done to him. Avon gives D'Angelo and Wallace a bonus for their good work. The police meanwhile get authorization to place taps for the pay phones used by D'Angelo and his crew but can only listen in when one of their suspects is using it meaning they'll have to keep the phones under constant observation. McNulty is in a tight spot when Major Rawls gives him a week to report back to his old job. When he realizes the connections McNulty's made in the various shootings, he announces he's going to arrest the Barksdales for murder and threatens to mess up the drug investigation.

Major Valchek gets back at Sobotka for the church gift fiasco, and a feud begins. Avon Barksdale continues to run his empire from a prison cell. On the waterfront, Port Police Officer Beatrice Russell gets stuck investigating the contraband in the The Greek's container. McNulty lends a hand with the investigation.

Lt Cedric Daniels lets it be known he is going to leave the department. McNulty pursues the identity of the Jane Doe found floating in the harbor. A pair of young longshoremen, Frank Sobotka's son Ziggy and nephew Nick, heist a container and sell its contents, digital cameras, to men working for The Greek.

Trying to let go of police work and return to his marriage, McNulty gives up on identifying his Jane Doe. The detectives look into Sobotka and his money. For his union, Sobotka tries to play the political game. D'Angelo wants to live life outside of Barksdale's umbrella and Bell brings in outside help for the problem.

Omar continues his bold strikes on the heavily guarded Barksdale stash houses. McNulty launches his own investigation into last year's prison suicide of D'Angelo Barksdale. On the streets the bloodbath continues, prompting Burrell and Rawls to jack up the heat on their district commanders. The street violence also presents Daniels with a tough decision. A beleaguered Cutty tries to get his life back on track.