The insecure Andrea Kuhn is encouraged by her psychiatrist to disclose her true feeling to her family, and when she is happy being herself, her husband accidentally kills her after an argument. Ruth recalls how stress triggered a depressive psychosis in George and his treatment with electroshock. Brenda has a miscarriage in the eve of her wedding day. Billy invites Claire to move to his place. David and Keith are discussing the alternative for their baby, adoption or to rent a belly. Rico misses a steady relationship while dating women from an Internet site.

Maggie Sibley's friend and fellow Quaker Peter Thomas Burns suffers a heart attack while watching a play, and Nate becomes intrigued about her faith when she brings it up. Brenda's blood tests reveal that her and Nate's child has a higher-than-usual possibility for developing Down's Syndrome or other complications at birth, and the doctor recommends amniocentesis to eliminate these factors. Ruth, feeling a misfit among other women in the sudden free time offered her without George, is displeased to hear that he wants the briefest divorce possible since he's already found another woman, so warns her she'd be marrying a depressed, sick man. Meanwhile, Rico is disgusted that sleeping with Vanessa is brief, to the point, and unenthusiastic, almost like another chore for him to help out with. Claire meets Ted, a lawyer, at work and eventually chooses to try to connect with him. David accidentally learns that Durrell will be performing in a school musical, and, remembering what it was like to have a parent who didn't have time to do it for him, he insists to Keith that they should go see him in it...despite the fact that Durrel's embarrassed enough about it not to want them to. After hearing Maggie admit her handicapped son's life was painful for her, Nate is inclined to agree with the doctor that Brenda should test to ensure there are no problems with her pregnancy, but Brenda is doubtful enough of his support to refuse.

Pilar Sandoval attempts to Rollerblade a steep hill while walking her dogs but literally doesn't make it when she loses control and is hit by a car. Brenda is upset with Nate's fists-up attitude toward the daughter they'll have, and is suspicious that his latest wish to attend Quaker meetings is simply to join Maggie. David, Nate, and Rico try but fail to agree on how to invest on the business, but it gives Rico a good opportunity to focus on pursuing his relationship with Vanessa. Ruth's babysitting experience with Durrel and Anthony goes sour when they don't return from playing basketball until Durrell drives the SUV home, and, only after David blames Ruth, is learned to have done it before. Later Durrell threatens Keith during a confrontation over it, and David learns from Anthony that he doesn't get they won't have to eventually leave. Ruth, encouraged by Claire to get a haircut, goes camping with Hiram again. Claire herself only attends Anita's show when Ted offers to tag along, and it goes smoother than she expects. The second night Nate attends a Quaker meeting with Maggie, Brenda goes there after her ultrasound with Jackie, only to find Nate absent, since he and Maggie got wrapped up talking and never went. As Brenda waits for his arrival, they sleep together...then Nate gets up, and immediately goes numb and collapses.