The West Wing staffers are introduced as each learns via phone or pager that the President was in a cycling accident. Josh faces the possible loss of his job after an on-air insult of a political opponent, which Toby tries to prevent by having Josh make a personal apology. Sam's fling the previous night with Laurie, who unbeknownst to Sam is a call girl, puts him in hot water, which he compounds when ineptly lecturing a class of 4th-graders about the White House and then asking their teacher which child is Leo's daughter. Leo must deal with the fallout from Josh's blunder, as well as 137 Cuban refugees who escaped on rafts and are seeking asylum. The president walks in during Josh's apology, recites the First Commandment, and lambastes three Christian pols for not denouncing a fringe group.

After a Republican commentator trounces Sam on television, President Bartlett decides to hire her over the objections of the staff. Josh and Toby mediate a conference between U.S. drug companies and an African President whose country is dying of AIDS.

The President and NASA plan a TV event for a probe's landing on Mars; satellite photographs show a suspicious-looking fire in Russia; Leo asks Toby and Josh to decide on the next postage stamp; Sam and C.J. have personal reasons for not wanting to accompany the President to a concert.

While a live TV show is broadcast from the West Wing following the State of the Union, the staff must covertly deal with a hostage situation in Colombia. CJ learns that a special guest at the state of the union has a black mark on his record that could taint the administration. Ainsley Hayes is afraid to meet the President in person.