Josh trumps a potential Democratic challenger in a masterful political move and then hires the challenger's chief of staff and ex-girlfriend Mandy Hampton. Toby tries to warn Sam away from his friendship with the call girl, but to Toby's horror, Sam seems intent on reforming her. CJ tries to spin the latest clash between President Bartlet and Vice President Hoynes. After an American plane is shot down carrying Bartlet's physician, Bartlet's response leaves Leo worried about the President's response.

A crucial banking bill is at risk when political rivals of environmentally sensitive President Bartlet attach a land-use rider to it that would allow strip-mining some of the Montana wilderness. C.J. tries to stamp out rumors that the Chief Executive chastised the Vice President during a cabinet meeting. An overworked Leo isn't too keen on his independent daughter Mallory dating the handsome Sam. C.J. continues to fend-off the romantic charms of a perceptive reporter with a knack for sniffing out juicy stories. Former lovers Mandy and Josh clash over the administration's attempt to jettison the land-use rider that might also ruin passage of the more important banking bill.

The President is rushed to hospital following a shooting; staffers field questions on protection measures and executive authority. Flashbacks show how key staff members joined the Bartlet campaign.

Josh finalizes a $6B health care plan that has strong support from both parties in both houses and appears to be a slam dunk for passage, but 78-year-old Senator Howard Stackhouse pulls a last-minute surprise--he wants money added for autism research or he'll filibuster. Thinking it's just a bluff, Josh blows off the senator, who then filibusters for more than eight hours while the WW staff waits desperately to begin their weekend with the episode unfolding as staffers write e-mails to their family members describing the evening's action. Elsewhere, Sam tries to eliminate various costly government documents, for which he's taken to task by a very young intern.