FBI agent Audrey Parker tracks a federal prison escapee who mysteriously dies shortly after reaching his hometown of Haven, Maine.

While Audrey tries to settle in as a Haven local and as a new police officer in town, she and Nathan investigate the seemingly random destruction of a local bar. When other strange events begin to occur - even targeting Audrey herself - they must race to figure what the connection could be, and what or who might be making them happen.

Audrey and Nathan investigate an upheaval at the local psychiatric hospital - where something happened to make the patients normal for a time, but sent their doctor into madness. As they track down the escaped patients, Audrey and Nathan discover that whatever caused the temporary reversal has begun to spill across all of Haven - making normal townspeople go dangerously insane.

Audrey sees an old photo in the local newspaper of a woman who could be her mother, she decides to investigate her family origins. Meanwhile, she and Nathan look into an epidemic that threatens the town's livestock and fields.

A dead body of an elderly man is found in a boat floating in the harbor; the man may have been there for at least a few days. The medical examination gives his age as somewhere in his thirties, but he definitely died of old age.

Audrey and Nathan have yet another bizarre case on their hands when a prominent member of the exclusive Haven Hunt Club is found in his car, mauled to death. It has all of the earmarks of a wolf attack and Chief of Police Wournos, who is also a member of the club, is all set to organize a hunting expedition to track and kill the animal. He reluctantly agrees to Audrey's request for 24 hours to investigate further and there are soon two other attacks, one by a bear and the other by a moose. The moose attack is most revealing since it turns out the animal was stuffed leading them to believe that supernatural causes are actually at work. Their investigation turns up two suspects: Landon Taylor, the taxidermist who stuffed the animals in the first place and Jess Minion who has a reputation for being a witch.

Audrey and Nathan investigate a series of unusual assaults on people. A man on a fishing boat has his limbs severely broken, a real estate agent is shredded, and a deck hand has his face erased. In the mean time Nathan and Jess, as well as Audrey and Duke, work on their flirting.

People at the clinic Jess works at are dying, and the surviving family members are blaming a shadow creature. Jess is attacked after she makes a discovery that could help Audrey and Nathan solve the mystery. Meanwhile, Jess and Nathan kick their relationship up a notch.

Audrey's birthday party is held at a nearby island resort during a storm. While there, a chameleon takes over the identity of one of the guests, leaving the group to figure out who it now is. At least one of the guests won't be returning to Haven alive.

Audrey tries to delve deeper into the Colorado Kid mystery with the help of Duke. Meanwhile, a series of explosions/fire related incidents take the lives of some of the townsfolk, which leads Nathan and Audrey to believe a school counselor is connected to the events.

Audrey's boss comes to town to get a report from her, and the find themselves in the middle of a heist aimed at recovering a smuggled box from Duke.

A family is plagued by a poltergeist.

We learn more about the cracks occurring in Haven.