Susan Lewis' boyfriend Div Cvetic, a psychiatric resident at County General, seems to be under a great deal of stress regularly lashing out at everyone. Doug Ross takes over for Mark Greene who takes a day off to be with his wife. He has a hard time keeping up with all the paperwork. John Carter is increasingly frustrated with Peter Benton who never seems to invite him to participate in surgeries. Benton learns the result of the fellowship he applied for and his mother shows up in the ER with a sprained ankle. Carol Hathaway treats a patient who was raped. A new ER aide, Bob, start work.

Doug Ross and Nurse Hathaway treat a girls' basketball team from a local catholic school for meningitis. Their teachers also need to be tested but one of them confides in Hathaway that she may have a particular problem. Green and the Chief of Staff have a disagreement in the middle of a procedure. With the wedding only two weeks away, Tag and Carol Hathaway have to deal with all of the final preparations, not the least of which is writing their own marriage vows. Susan deals with a suicide victim who is using emotional blackmail to keep his girlfriend from leaving him. Susan reaches the breaking point with her sister Chloe and tells her she has to move out.

Doug treats dying Chia-Chia. Mark however feels he's not doing the right thing for Chia-Chia.

Mark has to work for the fourth night in a row while a lot of the staff are absent and the number of patients is towering.