While the gang is quarantined in the lab for Christmas, they search for clues to solve the mystery of a skeleton found in a fallout shelter.

Booth seeks out the husband of a missing pregnant woman after her remains wash up onshore, but the suspect disappears. Meanwhile, Bones continues to clash with Cam, and Booth gets a visit from his ex.

After Howard Epps orchestrates an escape from his penitentiary, he starts picking off the Jeffersonian team one by one and taunting Brennan with clues to save them.

Brennan and Booth investigate the death of a Santa as Bones tries to give her father the Christmas he's always dreamed of, and Booth comes to terms with not spending the holiday with Parker.

While spending some time with his son, Booth finds a human finger. They find the body of a veterinarian. Hodgins starts to realize how he's been affected by the turmoil in his life.

Brennan and Booth investigate the remains of a bodyguard of two children who attend a high security school for the children of important people. Also, Cam hires Brennan's father as a teacher which causes some conflicts for Bones.

A corpse found roasted in a neighborhood party barbecue pit is identified as missing dentist Kurt Bissette. He had not only upset neighbors with his windmill and by nearly poisoning the gay couple's dog but probably was a blackmailer. Trey Johnson, the owners society's handsome young gardener, isn't the only one enjoying residents' infidelity, which isn't the only possible secret or motive either. Meanwhile young Parker seems worried about Booth's lack of female company. Sweets figures out why Arastoo faked his accent.

The team works to uncover clues buried under a life's worth of possessions saved by a hoarder in order to solve the mystery of his death. Meanwhile, Angela's father has a specific purpose for his most recent visit, and Brennan and Booth are confronted with unique opportunities.

From all over the world Brennan's former team reassembles to help Cam solve a difficult case of identifying an unknown baby's corpse, as her failure to do so may wreck her career. They soon realize this may not be just one case, but two.

Booth and Brennan's next case leads them to a crime scene where a human carcass has literally melted into the dashboard of a charred truck. As the team investigates the case, they discover a gunshot wound in the victim, but learn that neither the fire nor the bullet was the cause of the victim's death. Additional clues lead them to a local high school where the victim's wife is a teacher. As a student-teacher relationship begins to surface and a pattern takes shape in the lab, the team is able to track down the murder weapon and solve the crime. Meanwhile, Sweets resists the temptation of allowing his feelings for Daisy to interfere with helping her pass a government psychological evaluation, and Hannah attempts to break the ice and warm up to Booth's son Parker.

Metal hardware deliverer Tony Cole was fatally stabbed in a puzzling way. Booth is more preoccupied with his son Parker, finally back from England, and how to fit him in the family with Bones and baby sister Christine, and Sweets is through with counseling under false pretenses. Hodgins uses the case to prove his expensive 'pet' equipment is all useful. Tony had a bitter company rival, Karl Singler, and picked a fight with his beloved boy Danny's karate sensei, Hunter Sherman, over a fight with sprout Blake Sherman.

Brennan and Booth are to be married tomorrow, but not without a murder to solve. The team calls in all interns to help with the case so Brennan does not have to do anything.