Angel and the gang adjust to life at Wolfram & Hart, while Angel lets loose the shocking contents of a package from Sunnydale.

Angel and Spike challenge a necromancer who is unhappy with Wolfram and Hart's new leadership.

Angel saves a woman from a werewolf attack, but not before the woman was bitten. Now she will become a werewolf. As Team Angel tries to help her cope with her new situation, someone else would like to have Werewolf for dinner.

Fred faces technical and budgetary setbacks in her project to make Spike corporeal. Meanwhile, Spike is beset by grisly apparitions that only he can see.

When Lorne gets his sleep removed to prepare for the firm's Halloween party, he doesn't realize the consequences. At the party, everyone is mystically compelled to do what he tells them; Spike is thinking positively, Gunn is "marking his territory", Angel and Eve get a room, and Wesley and Fred are drunk. Things get worse when the sleep-deprived Lorne's empathic subconscious begins manifesting itself as a huge demon.

It turns out that the Wolfram and Hart postal worker is more than he seems; he and his brothers were once demon fighters, but he gave up after he lost his family to an Aztec warrior demon. When the demon comes to town, Angel must wrestle with his personal issues and help the last surviving member, 'Number Five', to rediscover his heroic side.

Wesley's father comes for a visit. With his father overseeing and critiquing everything he does, his old feelings of insecurity arise. Also, Wolfram and Hart is besieged by robot ninjas.

Spike receives a mysterious box in the mail, which emits a flash that somehow re-corporealizes him. He's thrilled to be solid again, but it also causes reality to start deteriorating at Wolfram and Hart; the Shanshu Prophesy is thrown into confusion by the presence of two ensouled vampire champions in the world. Angel and Spike's rivalry descends into a fierce brawl as they fight over a mystical grail in order to resolve the conflict.

Harmony is having trouble adjusting to working for Angel; she is unappreciated by her boss and snubbed by the other employees of Wolfram and Hart. Her troubles get a lot more serious when she flirts with a stranger in a bar and wakes up the next morning to find him dead in her bed - a man who happens to be the head negotiator in Wolfram and Hart's peace summit between two feuding demon clans.

Lindsey McDonald approaches Spike, introducing himself as Doyle and telling him that the Powers That Be have selected Spike to be their new champion now that Angel is working for Wolfram and Hart. Meanwhile, Angel has been infected by a parasite and slips into a series of feverish hallucinations in which his destiny as champion has been claimed by Spike.

A psychotic vampire slayer has escaped from her asylum, and is now on the loose in Los Angeles. Angel and Spike are on the hunt for her, before she does more damage. Once she is found, looking for pieces of her past, she believes that Spike was the man who drove her towards insanity, and wants to seek revenge.

Cordelia awakens from her magically induced coma and returns to help Angel fight an old enemy who has reappeared even more powerful than ever.

Angel's past comes to haunt him. An ally from World War II takes Fred, Gunn, and Wes hostage while seeking Angel. This is the only vampire Angel sired after he got his soul back. Angel relives the past and must determine his future.

Angel and the gang set out to foil an evil puppet show that is sucking the brain power of all the children who watch. During their fight, Angel is turned into a puppet himself and must rely upon his friends in order to reverse the spell which holds him at one foot tall.

When an ancient sarcophagus arrives in the laboratory at Wolfram & Hart, Fred opens a small compartment and is infected by an ancient disease that slowly begins to kill her. As Angel and Spike travel across the world in order to help her, Wesley slowly begins to realize that there may be no stopping this disease.

As Angel and the gang try desperately to bring Fred back, Wesley begins to understand that the ancient demon Illyria, now fused with Fred's body, is here to stay. Exhausting all options for saving Fred, the gang switches gears to stop Illyria and her plan for global domination.

Angel, Spike and Gunn travel to a surprisingly unusual hell dimension to free Lindsey and find out what he knows of the Senior Partners' ultimate plans. With Illyria's army defunct and her plans averted, the gang accepts her as a dubious ally. Wesley, volunteering to be her guide and mentor, falls slowly into depression and self-destruction. Meanwhile, the Senior Partners send a new, unstoppable force, a new liaison and businessman, named Marcus Hamilton, to find Eve, and Gunn makes an important decision in an attempt to protect his friends... and save his soul.

Parents bring their son to Wolfram and Hart to try to make sense of their son's superhuman abilities. Team Angel wants their assistance, but Angel refuses, because it's his son Connor. A demon is after Connor, but without his memories of his old life, he doesn't have much of a chance against the demon. True memories are revealed for Connor and a member of Team Angel

Illyria begins acting more strangely than usual. After she rescues Gunn from the suburban hell dimension, she begins displaying more power. After a hint from Hamilton, Wesley discovers that Fred's body is insufficient to contain Illyria's power, and she is about to explode. Meanwhile, Angel discovers that she is unintentionally leapfrogging through time, and uses it as possibly the only way to stop her. Also, Gunn begins to have suspicions about Angel being corrupted when he allows a demonic brethren to accept a pregnant young woman's baby as an upcoming sacrificial item.

Angel and Spike's mission to help resurrect a demon gang leader in Italy is made more complicated when they learn that their former love, Buffy, might be in danger. Meanwhile, when the Burkles make a surprise visit to Wolfram & Hart, Illyria solves the problem by showing Wesley a frightening talent- a talent that challenges his own moral standing.

The Team have reason to believe that Angel has been utterly corrupted with power when they find evidence that he has joined the Circle of the Black Thorn, the most evil of secret societies. Wesley, Gunn, Spike, and even Illyria discover some surprises when they urge Angel to side with the forces of Good again.

In the series finale, Angel reveals that his questionable moral behavior has been part of a bigger plan: to destroy The Circle of the Black Thorn and show the Senior Partners that the power of good can still make a difference. Wesley struggles with helping Illyria adapt to the world, scolding her for her attempts to take on Fred's form. As Gunn continues his quest of self-discovery, Lorne becomes more aware of the lack of happiness in the world. Harmony attempts to seduce Marcus Hamilton for information, Lindsey makes an important decision regarding his alliance, and Eve continues to deal with being mortal. As Spike comes closer to understanding the nature of heroism, Angel pays a visit to the one person he truly loves. On Angel's bidding, the gang goes out and spends each day as if it were their last...