Jeanette Louise Bradford has an allergic reaction to a bee-sting in Balboa Park, causing Keith to go to San Diego for his aunt's funeral and David to join him, encouraging him to discuss sleeping with a third man with him and to confront his father on his abusive childhood after the funeral. Russell admits he was sleeping with Olivier and an angry, betrayed Claire demands he leave her alone from now on. She and Ruth talk with each other about their relationship problems when Ruth learns Arthur is a virgin so there's nothing new to be gained from spending time with him. Vanessa is now again living life to the fullest, taking dance classes with Rico, but then collapses one night from too many medications. Billy, remarkably depressed after watching a poor video version of his and Brenda's beloved childhood book "Nathaniel and Isabel", kisses Brenda, who goes to visit Nate. Alone with Maya while Lisa goes to visit her sister's family in Santa Cruz, Nate consoles Benda until she begins to appear to want to become closer to him, and she quickly stops herself and departs. Keith and David are relieved to hear that Taylor is doing fine with Lucille and Roderick, but when Keith finally chooses to tell his father he's willing to forgive him for beating him and his sister, it's met with denial and quickly becomes a fight...and when David tries to calm both of them down for Keith's sake he's insulted by Roderick and unappreciated in his efforts by Keith, so leaves. When Nate calls Lisa's sister's, he learns Lisa hasn't yet made it to her place as expected, and isn't worried when he can't get through to her phone the first time...but he does start to be when he continues to call with no response.

A piece of "blue ice" broken off an airplane strikes Anahid Havanessian, whose husband goes to Fisher & Diaz for a funeral...but changes his mind when, frustrated with the government for hiding that such deaths are common and suspecting Nate's silence is indifference, he's snapped at by Nate, who then snaps at David and Rico for telling him he lost them money by not demanding payment for the meeting when they "switched to the local chapel". Walking in the early hours of the morning to clear his head without success, and drinking heavily and sleeping with a bar prostitute, he's in bad shape and can't accept the news of his mother marrying George. David and Claire are also reluctant, since David is worried about his brother and believes it should be delayed and Claire is worried they haven't known each other long enough to wed, but they know they'll marry either way. Claire visits her father's grave and learns, along with the fact that he's OK with the marriage himself, Lisa, Gabe Dmas, and her child are all with him. David is encouraged by his father to make up with Keith, which he does at church by talking with him so long they forget to go in. They're both present for their mother's wedding, but Nate isn't - after getting the news that Lisa has been found drowned, he continues to drink heavily and gets into a bar fight. Rico gets into a situation almost as bad when getting the bad news that his sister-in-law, despite being a nuisance, won't leave yet. Angry with Vanessa, he goes to dance class without her then is invited to a strip club where he sleeps with one of the dancers, Sophia. Brenda prepares to date, but not sleep with, her charming neighbor Joe. Nate finally leaves the bar after losing the fight, drives drunk, and is haunted by visions of Lisa and Nathaniel urging him to drive off a bridge, and finally ends up at Brenda's.