Captain Archer wants to convert curiosity into deeds and decides to enter a ship floating in space. Hoshi has trouble adjusting to life on Enterprise.

After helping to repair the warp drive on board of a Xyrillian ship, Trip notices a strange bulging on his arm.

Archer, Trip and T'Pol are captured by the Andorians at a Vulcan monastery on P'Jem. They believe that the monastery is being used to spy on Andoria.

Enterprise discovers a comet which contains the very rare element eisilium. Then unexpectedly a Vulcan ship arrives. Captain Vanik tells they're interested in human behavior.

Enterprise is sent to help the freighter Fortunate after an attack. However, its first officer, Ryan, is hiding something.

After an attack by a mysterious ship, Archers orders Enterprise's return to Jupiter to install phase cannons; Hoshi makes plans for Malcolm's birthday.

Phlox is asked to save the Valakians from annihilation by disease. However, he discovers something unusual about the Menk, another humanoid race on the planet.

Enterprise tries to rescue a Klingon ship from sinking into a gas giant.

T'Pol is being recalled because of Enterprise's involvement in the destruction of the P'Jem sanctuary. She and Captain Archer are later kidnapped while visiting the planet Coridan.

When Enterprise encounters a ship of Vulcan pilgrims, T'Pol is convinced by one of them to perform a Vulcan mind meld.

Lieutenant Reed discovers a rogue planet, which has broken out of orbit and therefore is devoid of any light. Life is still possible in some places because heat is bubbling up from under the surface, but T'Pol doesn't detect any humanoid life. Further scans however give a strange energy reading which seems to be coming from a ship on the surface. After the crew has landed, they encounter the Eska. The Eska come from another planet and they say they are hunting for the drayjin, an animal considered a delicacy. When captain Jonathan Archer tries to sleep on the planet, he hears a voice calling him by his name. A human female is wandering in the forest. Somehow he seems to know her.

Almost the entire crew is left unconscious when four Ferengi pirates raid Enterprise. A still conscious Trip is the only one who can get rid of them.

A fibrous, web-like alien creature comes aboard the ship and several of the crew becomes entangled in it including Archer and Trip, and it seems Hoshi is the only one who can try to communicate with the creature.

In 2370, Commander William T. Riker is trying to clear his mind and relives the last mission of the first Enterprise on the holodeck.