Baltimore Det. Jimmy McNulty finds himself in hot water with his superior Major William Rawls after a drug dealer, D'Angelo Barksdale who is charged with three murders, is acquitted. McNulty knows the judge in question and although it's not his case, he's called into chambers to explain what happened. Obviously key witnesses recanted their police statements on the stand but McNulty doesn't underplay Barksdale's role in at least 7 other murders. When the judge's raises his concerns at the senior levels of the police department, they have a new investigation on their hands. Lt. Cedric Daniels is put in charge with Kima Greggs as the lead detective. As for Barksdale, he finds himself demoted to a low-level dealer after his arrest and he obviously has to prove himself yet again.

After two weeks on the job, the team still doesn't have a photo of their principal target, Avon Barksdale. Freamon has a solution when he hears Avon was a Gold Gloves boxer. In the aftermath of the near riot at the towers, Lt. Daniels stands by his men even though he thinks they were stupid to do what they did. He's ordered to lead a raid on the low-rise units in the projects but McNulty rebels and refuses to participate in a raid that's just being put up for show. Dissatisfied with the antiquated equipment they have to work with, McNulty asks his friend at the FBI to lend them listening devices. His friend also has some information for him about Lt. Daniels. D'Angelo isn't around when a gang led by someone called Omar robs his stash.

Lt Cedric Daniels lets it be known he is going to leave the department. McNulty pursues the identity of the Jane Doe found floating in the harbor. A pair of young longshoremen, Frank Sobotka's son Ziggy and nephew Nick, heist a container and sell its contents, digital cameras, to men working for The Greek.

The brutality at police headquarters continues over the perceived failure of department commanders to rein in the city's crime stats. Another hit by Omar on the Barksdale stash houses goes horribly wrong. Proposition Joe summons Stringer Bell to a meeting and tells him that the cops have screwed up. Daniels reassigns his detail after the wire on Stringer Bell goes dead.

Johnny pressures Bubbles to stop snitching for the detail. Cutty lies to his grandmother about going straight. McNulty realizes pursuing Barksdale and Bell is a losing cause, so he turns his attention to nailing Kintel Williamson. Colvin's free drug dealing zone, now known in the streets as Hamsterdam, scores a small victory. Avon Barksdale emerges from prison to a warm welcome from Stringer Bell.

Avon readies his troops for a seemingly endless war against Marlo. The detail works towards the top rungs of the Barksdale organization with the information garnered from the wire. While Royce continues to grapple with Amsterdam, Burrell offers a deal to minimize the fallout. Carcetti's political plans become obvious to his friend and fellow councilman Tony Gray. Bubbles offers his view of the world. McNulty changes tack.

In the Season Four premiere, four boys from West Baltimore play out their summer vacation in the streets. Meanwhile, Marlo has solved the problem that baffled Stringer Bell: how to maintain discipline--read: murders--without getting police attention.

Herc's soft-duty job with the mayor takes an unexpectedly hard turn. Despite the potential damage to her career, Pearlman provides Freamon and Sydnor with subpoena ammunition for their 'grizzly bear' hunt in City Hall.

Poot returns to the corner after a stint in prison--and is welcomed back. Carcetti engages in a testy budget battle with City Council President Campbell, promotes Daniels, and hits a snag in his efforts to relieve Burrell of his duties.

After flexing his muscles around the city, Carcetti faces his first dilemma when a group of ministers protests Herc's mistreatment of one of their own. Randy gets the cold shoulder at school. Omar and Reynaldo pay a menacing visit to Proposition Joe, with their own proposition. Freamon has a revelation at a crime scene that promises to blow the lid off an unsolved mystery.