D'Angelo speaks to Wallace, who tells him he wants to go back to school and get out of the Game. However, Malik 'Poot' Carr (Tray Chaney) discovers Wallace has started using cocaine to help him deal with his guilt over Brandon's murder. Freamon gets Sydnor and Prez started on the complex Barksdale money trail, including possible political connections, and they are surprised to find Avon's corporations have been buying up vacant buildings in run-down parts of the city. Greggs and Freamon approach D'Angelo's girlfriend, Shardene Ennis (Wendy Grantham), who works at Orlando's, in the hopes they can turn her into a CI. After Bubbles narrowly avoids a beating whilst stealing a package that turns out to be stepped on, he decides to try to get clean. Avon and Eastside kingpin 'Proposition' Joe Stewart (Robert F. Chew) stage the annual East vs. West basketball game, but when the detail follows Avon afterwards, they get something they never expected. Meanwhile, having already killed Stinkum, Omar sets in motion a plan to gain revenge on Avon for Brandon's death.

Detective Jimmy McNulty finds the body of a woman floating in the water while carrying out his new assignment of Harbor Patrol. Major Valchek has his gift to a local parish trumped by Frank Sobotka, his rival in the local stevedores union. And on the waterfront, a shipping container destined for 'The Greek' bakes in the sun with perishable cargo.

After the notorious Franklin Terrace public housing towers are razed, the Barksdale drug crew searches for a new home on the streets of West Baltimore. McNulty and the detail look to make a case against Stringer Bell with a wiretap on a drug ring run by his ally, Proposition Joe. Daniels' promotion is derailed by City Hall due to his estranged wife's political ambitions.

The brutality at police headquarters continues over the perceived failure of department commanders to rein in the city's crime stats. Another hit by Omar on the Barksdale stash houses goes horribly wrong. Proposition Joe summons Stringer Bell to a meeting and tells him that the cops have screwed up. Daniels reassigns his detail after the wire on Stringer Bell goes dead.

Daniels goes ballistic when the detail gets reassigned to the Western District. Stringer Bell learns from Donette that Brianna is thinking about talking to McNulty. Bunk receives a gift wrapped surprise. A single cell phone allows Freamon to begin mapping out a communications network for the Barksdale organization. Marlo dispatches a drive-by on a Barksdale drug corner.

Prez impresses the detail with what he's found out from Bodie's cell phone, information that sends McNulty and Greggs on a road trip. Colvin sees the benefits of his plan working. Carcetti confronts a hurdle he must clear if he wants to run for higher office, while Marlo appears to take the bait set by the Barksdale crew.