The President is rushed to hospital following a shooting; staffers field questions on protection measures and executive authority. Flashbacks show how key staff members joined the Bartlet campaign.

On this year's "Big Block of Cheese Day", a college friend of Donna's asks Sam to help her get her late grandfather, accused of being a Communist spy inside the U.S. government, a presidential pardon; dealing with the recent revelation that his father had been having an affair for the past 27 years, Sam faces off with an F.B.I. agent, and later with Nancy McNally, over the pardon. Elsewhere, a group of cartographers completely re-educates C.J. on her perception of the globe, and one-time protester Toby, with the help of a straight-talking female security guard, speaks for the w.h. at a rally to protest against U.S. participation in the WTO and various free trade agreements.

With hypothetical polling numbers showing them it will be political suicide, staffers prepare to announce the President's condition. As they do, a military crisis flares up in Haiti and Josh faces off against two senators who are against the Government's tobacco industry suit. But as badly as the day seems to be going, a tragedy will come from a car wreck at 18th and Potomac that will affect everything.

As the Haitian army continues their seizure of the American embassy there, Bartlet and the staff prepare for the announcement that Bartlet has M.S. and the President must decide whether or he will seek re-election. As the funeral for Mrs. Landingham takes place and the announcement draws nearer, Bartlet thinks back to his past in search of the answer to the question everyone is asking: Will he seek re-election?

The staff is hunkered down in the Bartlets' hometown of Manchester, N.H., where they work with political consultants Bruno, Doug and Connie on the president's official announcement that he'll be seeking a second term; meanwhile, they all lament various W.H. events of the previous four weeks, including a huge strategic mistake by Josh, a pivotal FDA announcement scheduled for the same day as the president's speech, an ongoing battle between then president and first lady, and a major press room gaffe by C.J.

With the staff all bickering with one another in Manchester, especially adversarial speech writers Toby and Doug, who angrily disagree about whether Bartlet should make a public apology for lying about his MS, and with the president sniping at everyone, the second-term announcement speech is locked. Abby ultimately forgives the president for deciding to run again without discussing it with her, and he ultimately apologizes to the staff in private for keeping his condition from them, which they expect will soon lead to a whole slew of grand jury subpoenas.

While the W.H. is hosting a gala dinner for Nobel Prize winners, Leo and the president learn of a suicide bomb in an Israeli cafe that took the lives of two American students in Tel Aviv for a soccer match, and the staff attempts to manage the president's first veto, of a House bill eliminating the estate tax, and the threat of an override the same night. Sam and Toby first try to sway a contentious Dem. From Tennessee who wants a whole list of farming and ranching concessions in exchange for his vote and three proxies; after a pep talk from Leo, they devise a substitute plan that may prove even more effective, if it works. Josh takes the governor of Indiana into a private meeting to determine if the man plans to challenge Bartlet in Democratic primary. C.J. takes heat from a smarmy Dallas entertainment reporter who is in town for the Nobel dinner but winds up having to cover the veto and override vote, but after the reporter embarrasses her during a live stand-up, C.J. one ups the woman in front of the press corps. Later, Sam, Toby and Josh try to help the president decide what to say to the parents of the two murdered students.

When the military loses contact with a submarine in hostile waters, the President must choose between risking the lives of the crew and provoking North Korea. CJ relishes the Majority Leader's flubbing of an interview. Babbish informs Abby that she is the weak link in the President's legal defense.

CJ cannot control her outrage when the US agrees to an arms sale to Qumar, a country that brutally abuses women. Josh meets with Amy Gardner, a leading women's group lobbyist. The content of a Smithsonian exhibit draws protest from a veteran's group. Leo and the President discuss options when the possibility of a Mad Cow infection strikes the US beef industry.

A small town in N.H. is the site of the first presidential primary vote, and the results from Hartsfield's Landing, announced at 12:07 a.m., will dominate the news all day until the final tally. Josh wants favorable press for the president, prompting him to ask Donna to persuade a local couple she knows to reconsider their vote. Elsewhere, Bartlet has just returned from India with a collection of antique chess sets he gives as gifts to the staff. He plays Toby while they discuss their recent blow-up, Bartlet's insomnia and Toby's fervent belief that the president's enormous intellectual gravitas is an asset, not a liability, to the campaign. He also plays Sam as they discuss a critical detente standoff between China and Taiwan. And Charlie and C.J. stand off in a series of pranks over a missing copy of the president's private schedule.

Donna teaches Toby and Josh an important lesson as their trek homeward continues; Sam staffs the President in Josh's absence and welcomes an old friend home; Bartlet hires a secretary and C.J. finds a Big Brother for Anthony; the situation in Qumar continues to escalate; Bartlet gets spooked by a photo op as the Dow continues its dive; and a pipe bomb kills 44 students at a Midwest university swim meet.

The assassination of Shareef threatens to become public, the president speaks at Zoe's graduation, and the unthinkable happens.

In the wake of his daughter's kidnapping, Bartlet must make a decision between being a father and being President.

Seven hours have passed since Zoey's kidnapping and and the Republicans are in charge of the White House. Rifts are appearing in the leadership of both parties further complicated by the arrival of a ransom note demanding the release of terrorists.

Zoey Barlet has been held for over a day. An international crisis looms that could have serious repercussions for the administration, let alone the hostage.

A nuclear device is tested in the Indian Ocean, but none of the known nuclear powers will claim responsibility, leading to the possibility of a terrorist group holding missile tests. Vice President Russell, heretofore dismissed by west wing staff as a joke, a four-term congressman alleged to be securely in the pocket of a large Colorado mining company, recalls a junket he'd taken early in his political career in which a drunken Israeli statesman confessed to secret missile tests. Russell visits the sit. room and puts the military and national security leaders at ease, leading the president and Leo to reassess the man's political gravitas. Bartlet then drags the Israeli p.m. to the White House, where they debate the power of the U.S. to dictate which states should have nuclear capabilities.

The president and staff are about to head for Brussels to sign an international free trade deal that Josh has just spent a lot of time and effort negotiating, to nearly everyone's satisfaction; at the 11th hour, the CEO of an IBM-like company tells Josh that the first effect of the new agreement, of which his company is a huge beneficiary, will be the immediate transfer of 17,000 programming jobs to India; the head of the communications workers' union, which is representing the affected programmers, brings one of the programmers to Josh's office, and they refuse to leave, leading Josh to question the underlying adverse effects of the trade deal. Throughout the episode, Ryan tries to make Josh care that he's completing his internship that day, while Donna pesters Josh to bring her on the Brussels trip in an effort to make her a more active player in west wing activities, eventually leading to a trade-off that will mean even bigger things for Donna in the long run.

C.J.'s first day as Chief of Staff gives her a new appreciation for Leo's skill in the role. While struggling to keep up with her hectic schedule, she must handle the sudden appearance of abandoned Soviet nuclear material, counter political maneuvering within the Cabinet, and assert her authority with the staff and the President. Toby conducts a press briefing after which C.J. orders him to quickly find someone to fill the role permanently. The Democratic Party enlists Josh's help to talk Congressman Matt Santos out of taking an early retirement.

President Bartlet and his current and former staffers come together for Leo's funeral.

Eyebrows are raised when the President-elect places a call to the president of China and offers a different position than that of Bartlet. Meanwhile, Josh picks his deputy chief of staff.