D'Angelo speaks to Wallace, who tells him he wants to go back to school and get out of the Game. However, Malik 'Poot' Carr (Tray Chaney) discovers Wallace has started using cocaine to help him deal with his guilt over Brandon's murder. Freamon gets Sydnor and Prez started on the complex Barksdale money trail, including possible political connections, and they are surprised to find Avon's corporations have been buying up vacant buildings in run-down parts of the city. Greggs and Freamon approach D'Angelo's girlfriend, Shardene Ennis (Wendy Grantham), who works at Orlando's, in the hopes they can turn her into a CI. After Bubbles narrowly avoids a beating whilst stealing a package that turns out to be stepped on, he decides to try to get clean. Avon and Eastside kingpin 'Proposition' Joe Stewart (Robert F. Chew) stage the annual East vs. West basketball game, but when the detail follows Avon afterwards, they get something they never expected. Meanwhile, having already killed Stinkum, Omar sets in motion a plan to gain revenge on Avon for Brandon's death.

In the Season Four premiere, four boys from West Baltimore play out their summer vacation in the streets. Meanwhile, Marlo has solved the problem that baffled Stringer Bell: how to maintain discipline--read: murders--without getting police attention.

With Freamon and Greggs moved to Homicide, Herc and Dozerman join Marimow in the stripped-down Major Crimes Unit. Cutty gets a 'custodial' job at Tilghman School mopping up truants, but can't make headway in his efforts to mentor Michael.

The ensuing negative attention turns Royce against Burrell, who takes the heat while Rawls comes to the rescue. At school, Prez's reward/punishment program meets with mixed results, and Colvin looks to restore order by separating disruptive "corner" kids from more attentive "stoop" ones. Chris tries to enlist Michael into Marlo's ranks, spooking Randy along the way. Dukie debunks Randy's "special dead" theory.

With Election Day approaching, the three mayoral candidates make last-minute appeals. Carcetti wrangles for votes as he responds to a potentially devastating smear. Norris and Greggs get a lead on the Braddock case, but end up being detoured.

With a bounty on him, Omar calls in a favor to Bunk. The election over, Royce and Carcetti make peace and contemplate their futures. At school, Prez tricks his students into learning math. Finally, Greggs uses 'soft eyes' at a crime scene.